https://padlet.com/magani_c/41cx87wamb0c732i Review the resources provided in the last column. Answer the questions with your group, make sure to be detailed and use original language. en-us 2022-09-27 16:57:27 UTC 2022-09-29 00:14:19 UTC hello@padlet.com magani_c https://padlet.com/magani_c/41cx87wamb0c732i/wish/2315990045 Webpages:

https://aabme.asme.org/posts/single-chamber-bioreactor-grows-both-bone-and-cartilage

https://www.science.org/doi/10.1126/sciadv.aay2387

https://stemcellres.biomedcentral.com/articles/10.1186/s13287-018-0847-8

]]> 2022-09-27 16:59:32 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2315990045 10545541 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007161 A bioreactor is a device that constructs bone and cartilage in a single chamber. ]]> 2022-09-28 17:52:45 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007161 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007342 A bioreactor is a device that mimicks human conditions to create tissue as a replacement for the human body. It is mostly used to create bones for people who don't have that bone. ]]> 2022-09-28 17:52:53 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007342 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007558 A bioreactor is a small chamber in which a bone could grow and develop. It is a manufactured device that provides the bone with a biologically active environment in order to help the bone and cartilage properly gain mass.]]> 2022-09-28 17:53:01 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318007558 10570691 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318008567 A bioreactor is a chamber that grows pieces of cartilages and bones. This allows for studies of bone and cartilage interactions and joint diseases in order for scientists to create medications or implants for patients. ]]> 2022-09-28 17:53:37 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318008567 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318009237 A bioreactor is a piece of technology that is made up of a container used to grow bones and cartilage. ]]> 2022-09-28 17:53:58 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318009237 1057963 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318010703 A bioreactor is an incubator that grows bones and cartilages. It can also culture tissues. The bioreactor consists of an inner chamber and is surrounded by a ring that inserts fluids that nurtures the bone. This fluid´s pressure is controlled to manipulate accordingly to the body part´s growth.]]> 2022-09-28 17:54:49 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318010703 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318012696 A bioreactor is a machine that is able to create an environment where biological reactions can take place. Under the right the conditions, it can be used to grow and shape bones.]]> 2022-09-28 17:55:56 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318012696 10581481 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318013018 Using animal bones or other humans' bones risks rejection from the immune system or infection. If we can use bioreactors to custom-design bones using the patient's own stem cells and have it fit perfectly inside of the body, this lowers the casualties of bone transplants and is more effective for the patient.]]> 2022-09-28 17:56:08 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318013018 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318014632 A bioreactor is a chamber that grows constructs of bone and cartilage. The bioreactors produce constructs that resemble natural joints and are small enough to fit into 96-well arrays. ]]> 2022-09-28 17:56:59 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318014632 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318014726 Bioreactors develop bones by providing them with an active environment. Without the proper stimulants, the bone would not know to grow stronger and instead turn out weak and frail. The device also provides the bone and cartilage with an appropriate setting similar to the conditions inside of the human body.]]> 2022-09-28 17:57:00 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318014726 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318016414 It develops the bone by synthesizing cells. It comes from the human body and is placed into the artificial bone frame. It is 3D printed and used to replicate a real bone and the materials used are seeded with your own cells. ]]> 2022-09-28 17:57:51 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318016414 10545261 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318016421 A bioreactor is a device that was designed to create an optimal environment for synthetization of tissue to create bones. It enforces the tissue under lots of controlled pressure constantly to create the specific shape and strength of the bone for the individual.]]> 2022-09-28 17:57:51 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318016421 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318022355 This innovation is important because it can be used to help people with disablities, so that they can do everyday activites. It is also important because it is more effective for bone transplant, and it can be more stronger because its a new bone compared to a bone from a dead animal. ]]> 2022-09-28 18:00:57 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318022355 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318023711 The bioreactor has two sets of inlets and outlets, one set on the bottom of the reactor to provide fluids for bone growth and other on the top to serve the cartilage. They adjust pressure, as they grow thicker so the nutrients continue to move through the ECM and then onto the next bioreactor. ]]> 2022-09-28 18:01:42 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318023711 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318023752 Bioreactors are very important due to the fact that they ensure that is cells are protected through various nutrients as well as allowing products to be produced in large quantities. Bioreactors also instruct cells on how to build tissue structures as well as keeping up the organization of them. These designs offer an increase in oxygen and the decrease of stress overall. Bioreactors help allow bones to be proportionate and more potent, where patients can live freely. ]]> 2022-09-28 18:01:43 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318023752 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318024669 It is important to have an innovation like this because it helps lower the risks of bone transplant casualties. By using a patient's own stem cells to make bioreactors we increase the possibility of the bone transplant working. This compared to using the bone of a dead animal can be more beneficial for a patient.]]> 2022-09-28 18:02:15 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318024669 10550361 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318024880 The bones develop by the bioreactors that produce constructs that resemble the natural joints and they are small enough to fit into 96-well arrays. Also they develop by providing them in an environment that is always active. ]]> 2022-09-28 18:02:22 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318024880 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318101666 The bioreactor is an important innovation due to the safety of bone transplants. Creating a bone made from the patient's own stem cells makes it easier for the body to adapt to it. If the bone of a dead animal is used, there is a risk of infection and the effectiveness of the bone can be lowered.]]> 2022-09-28 18:47:58 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318101666 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318404690 The bioreactor has the potential to improve many lives. Over 10 million people in the United States suffer from bone disorders. Because the bioreactor creates a bone specific to the patient, with their stem cells and everything, the chances of a successful transplant are high. ]]> 2022-09-29 00:11:09 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318404690 https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318408899 From cultivating the bones' stem cells to providing the environment required for the bone to develop, the bioreactor works to develop strong and healthy bones. The first step is to 3D print the bone to replicate the original shape. After that is done, the bioreactor provides the rest of the fluids and pressure required. ]]> 2022-09-29 00:14:19 UTC https://padlet.com/magani_c/41cx87wamb0c732i/wish/2318408899