History : In 1885, Karl Benz, a German engineer, designed and built the world’s first practical automobile, the Benz Patent-Motorwagen. The first successful test drive took place in Mannheim, Germany. In 1888, Karl’s wife, Bertha Benz, famously undertook a 106-kilometer journey in the Motorwagen to demonstrate its reliability and practicality, effectively marking the beginning of the automobile industry.

History : In 1895, German physicist Wilhelm Conrad Röntgen discovered X-rays while experimenting with cathode rays in his laboratory. Röntgen's first X-ray image was of his wife’s hand, showing her bones and wedding ring.

History : In 1876, Alexander Bell, a Scottish-born inventor living in Canada and the United States, created the first practical telephone.On March 10, 1876, Bell made the first successful call to his assistant, Thomas Watson, saying, "Mr. Watson, come here, I want to see you."

History : In 1921, Canadian scientist Frederick Banting, working with his assistant Charles Best, discovered insulin, a hormone critical for regulating blood sugar.

Their breakthrough came when they successfully administered insulin to diabetic patients, significantly reducing blood sugar levels and saving lives.