Discussion Board 2 by Abby Stacks https://padlet.com/abbystacks/2q6erqa43orhhxpv en-us 2023-03-06 21:52:50 UTC 2023-03-07 19:14:01 UTC hello@padlet.com Sympathetic responses: (EPI and NE transmitters) abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848660 A1: arteries and veins- vasoconstriction, iris muscle of eye- contraction/dilation

A2: adrenergic nerve ending- decreased release of NE

B1: heart- increased heart rate, forced contraction

B2: (not stimulated by NE) bronchiolar smooth muscle- bronchodilation, uterus- relaxation, coronary and skeletal muscle blood vessels- vasodilation]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848660 Parasympathetic responses: (ACH) abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848661 1. arteries- not supplied by  cholinergic nerves
2. heart- decreases HR, and AV
3. intestines, secretion, and GI motility- increases
4. postganglionic NT- ACH released
5. pupil of eyes- constriction/miosis
6. lower respiratory passages- bronchoconstriction
7. urinary bladder- contraction
8. urinary sphincter- relaxation]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848661 Sympathetic division drugs: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848662 Alpha 1: 1. adrenergic agonists MOA- contraction of smooth muscle, increases BP,  vasoconstriction
2. adrenergic blocking drugs MOA- relaxation of smooth muscle, vasodilation, decreases BP, increases urine flow

Alpha 2: adrenergic agonists MOA- bronchodilator, cardiac stimulant, vasopressor/vasoconstriction, increases BP

Beta 1: 1. adrenergic agonist MOA- (low dose) vasodilation and increased renal blood flow, (medium dose) increases force of contraction and cardiac output, (high dose) vasoconstriction, increases BP

Beta 2: 1. adrenergic agonist MOA- bronchodilation, relaxation of smooth muscle in lungs and uterus

Beta 1 and 2: adrenergic blocking drugs MOA- decreases force of contraction, cardiac output, HR, conduction and due to decreased cardiac output- BP is decreased, can cause bronchoconstriction


]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848662 Parasympathetic division drugs: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848663 Cholinergic Direct: acting cholinergic agonists MOA- mimics ACH, bind to the muscarinic receptors in the cholinergic/parasympathetic division 

Cholinergic Indirect: acting cholinergic agonists MOA- increases ACH, inhibit acetylcholinesterase

Anticholinergic: MOA- bind to a cholinergic receptor, acts as a blocking drug/ antagonist]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848663 Sympathetic specific drugs: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848666 A1: adrenergic agonists-
1. ephedrine
2. phenylephrine (Neo-Synephrine®)

A2: adrenergic agonists-
1. epinephrine (Adrenalin®)

B1: adrenergic agonists- 
1. dobutamine (Dobutrex®)

B2: adrenergic agonists- 
1. albuterol (Proventil®, Ventolin®)
2. terbutaline (Brethine®)
3. formoterol (Foradil®)
4. salmeterol (Serevent®)

A1: adrenergic blocking-
1. prazosin (Minipress®)
2. terazosin (Hytrin®)
3. doxazosin (Cardura®)

B1: adrenergic blocking- 
1. atenolol (Tenormin®)
2. metoprolol (Lopressor®)

B2: adrenergic blocking- 
1. nadolol (Corgard®)
2. propanolol (Inderal®) 
3. timolol (Blocadren®)

]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848666 2 divisions of ANS abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848667 Sympathetic Nervous System
(fight or flight)
-Adrenergic

Parasympathetic Nervous system
(rest and digest)
-Cholinergic]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848667 Sympathetic/ Adrenergic Receptors: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848668 1. Alpha 1- found on glands, eyes, smooth muscle, and most arteries and veins
2. Alpha 2- found at adrenergic nerve endings
3. Beta 1- found on the heart
4. Beta 2- found on smooth muscle, lungs, uterus, skeletal muscle arteries, and coronary arteries]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848668 Parasympathetic/ Cholinergic receptors: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848669 1. Muscarinic- found at cardiac muscle, smooth muscle, and glands
2. Nicotinic 1 (Nn)- found at ganglia of parasympathetic nerves and sympathetic nerves 
3. Nicotinic 2 (Nm)- found at neuromuscular junctions ]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848669 ANS Sympathetic Neurotransmitters: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848671 -Norepinephrine (NE)
-Epinephrine (EPI)
-Dopamine (DA)
-Acetylcholine (ACH)]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848671 ANS Parasympathetic Neurotransmitters: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848672 -Acetylcholine (ACH)]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848672 ANS Sympathetic Neurotransmitters released: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848673 -Norepinephrine (NE): released at postganglionic nerve endings
-Epinephrine (EPI): released by adrenal medulla at the adrenergic receptors
-Dopamine (DA): precursor to NE, released at hypothalamus
-Acetylcholine (ACH): released at ganglia from presynaptic nerve endings ]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848673 ANS Parasympathetic Neurotransmitters released: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848674 -Acetylcholine (ACH): released at ganglia from presynaptic nerve endings ]]> 2023-03-06 21:52:50 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505848674 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505849098 2023-03-06 21:53:21 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505849098 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505850435 2023-03-06 21:55:15 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505850435 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505856796 2023-03-06 22:03:00 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505856796 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505859824 2023-03-06 22:07:25 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505859824 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505864249 2023-03-06 22:13:14 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505864249 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505865636 2023-03-06 22:15:30 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505865636 abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505868947
  • Unit 2 ANS ppt part 1 - slide 8
  • Unit 2 ANS ppt part 1 - slide 10
  • Unit 2 ANS ppt part 1 - slide 15
  • Unit 2 ANS ppt part 1 - slide 16
  • Unit 2 ANS ppt part 1 - slide 20-26
  • Unit 2 ANS ppt part 2 - slide 5
  • Unit 2 ANS ppt part 2 - slide 3
  • Unit 2 ANS ppt part 2 - slide 10
  • Unit 2 ANS ppt part 2 - slide 12
  • Unit 2 ANS ppt part 2 - slide 15
    • ]]>     2023-03-06 22:20:17 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2505868947     Parasympathetic Specific Drugs: abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2507396007 Cholinergic Direct: Acting Cholinergic Agonists
    1. acetylcholine 
    2. pilocarpine (Pilocar®)
    3. bethanechol (Urecholine®)

    Cholinergic Indirect: Acting Cholinergic Agonists
    1. neostigmine (Prostigmin®)

    Anticholinergic: 
    1. atropine
    2. dicyclomine (Bentyl®)
    3. ipratropium bromide (Atrovent®)

    ]]>     2023-03-07 18:51:02 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2507396007     abbystacks https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2507397185 2023-03-07 18:52:01 UTC https://padlet.com/abbystacks/2q6erqa43orhhxpv/wish/2507397185