Contrast Media mind map by https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx en-us 2020-10-18 21:54:28 UTC 2024-11-30 07:24:29 UTC hello@padlet.com Radiolucent (black) alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839273823 -gaseous substances w/ low atomic no.
-low Z allows for photons to pass through (decreases beam attenuation)
- Air: readily absorbed by body. Causes gas emboli in bloodstream. (okay to inject into synovial joints or into GI track)
-O2: readily absorbed by body. Causes gas emboli.
-C02 & NO are readily absorbed by body and safe to use. ]]> 2020-10-18 21:59:32 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839273823 Radiopaque (white) alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839280486 - High Z. increased beam attenuation= brighter image. 
-Delivered Parenteral or enteral (Meglumine & Diatrizoate sodium= used for oral or rectal admin during GI tract exams in place of barium
-Classified by Chemical structure & Osmolality
-contraindications: perforations: Extravasation 
-all have higher osmolality than saline & blood plasma. 
]]> 2020-10-18 22:08:11 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839280486 Ionic CM alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839284214 2020-10-18 22:13:14 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839284214 Negative CM alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839289653 2020-10-18 22:20:28 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839289653 Barium Sulfate (56) Positive CM alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839291982 2020-10-18 22:23:26 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839291982 Nonionic alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839294445 -LOCM: 300-484 mOsm/kg water
- 3 Iodine atoms to each position (2,4,6), 1 benzene ring. 
-3:1, 3 iodine atoms per molecule to 1 osmotically active particle (won't dissociate) = a media of 3.0. 
-Larger molecule = more viscus=Lower osmolality= less toxic= Low osmotic effects
-More water soluble (hydrophilic)
-More water soluble in blood plasma
-No ionic breakdown, LACK SALTS!!
-remove cation (salt), replace with glucose 
-Less toxic at cellular level/ more tolerable
- can be warmed to decrease viscosity
-ex: Optiray, Visipaque AKA iodixanol 

]]> 2020-10-18 22:26:42 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839294445 Radiopaque (white) alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839300715 -used in GI exams 
-delivered Enterally
-not metabolized by the body. 
-High Z. increased beam attenuation= brighter image.
-Contraindications: perforations= Ba Pari ]]> 2020-10-18 22:34:21 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839300715 Iodine-based (53) Positive CM alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839318201 2020-10-18 22:51:47 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839318201 HOCM: 1800-2100 mOsm/kg water alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839330452 -Monomers: 1 triiodinated benzene ring w/ 3 iodine atoms per molecule attached at positions 2,4,6
-will disassociate in blood into 2 active osmotic particles (-anion, +cation) = highly osmolar increases adverse reactions.
- low molecular weight= less viscus, more toxic, Highly osmotic
-3:2  3 iodine to 2 particles = 1.5 media 
-1 benzene ring labeled 1-6. 
pos. 1.) neg. acid group that forms salts & where dissociation happens. 
pos. 2,4,6.) are triiodinated 
pos 3 &5.) side groups that determine class of osmolality.   ]]> 2020-10-18 23:06:17 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839330452 LOCM: 600-850 mOsm/kg water alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839330613 -Dimers: Large molecule composed of 2 identical simpler molecules (2 benzene rings. same basic carbon structure. labeled (1-6). 
1 acid group and 6 Iodine atoms per molecule)
-6:2 means 3:1 = 3:0 media 
-Low osmotic effects b/c more Viscous (higher molecular weight) 
-High contrast due to number of iodine atoms per molecule (have 6)
-will still disassociate in the blood but the dimer's large structure makes for less side effects.  
-ex: Ioxaglate meglumine, ioxaglate sodium/Hexabrix
]]> 2020-10-18 23:06:29 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/839330613 Types of HOCM alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/854345196 -Diatizoate Sodium: 3:2  dissociates into anion =3iodine atoms  
and sodium: osmotically active cation.
-Metrizamide:3 iodine atoms, no cation or anion]]> 2020-10-22 21:45:43 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/854345196 Iodine-based enteral contrast alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/859586890 Meglumine & Diatrizoate sodium
-Some absorbed through mucosa and excreted through kidneys
-Most passed through rectum
-if Ba is not contraindicated, Ba is preferred as Meglumine, Diatrizoate sodium is highly osmotic and will draw fluid and dilutes iodine= bad contrast can lead to adverse reactions like dehydration vomiting, diarrhea.
]]> 2020-10-25 17:01:59 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/859586890 Molecular Structure Comparison alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/866688371 2020-10-27 17:09:53 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/866688371 alexisschneider1 https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/866694060 2020-10-27 17:11:00 UTC https://padlet.com/alexisschneider1/2ghwrhibejfsf1dx/wish/866694060