Silver Team October 2025 by Kimberly O'Hara

kimberlyohara1 — 2025-10-07 21:55:42 UTC

Kim's office: 7-7665

Cell: 412-855-1375

kimberlyohara1 — 2025-10-08 19:26:43 UTC

No significant difference in coronary artery lesions after 6 months between IVIG + high-dose aspirin and IVIG + low-dose aspirin groups - but no changes to AHA guidelines or to our institutional practice yet! A larger study from China is coming!

Pearls: High-dose aspirin for anti-inflammatory effects; low-dose aspirin for anti-platelet/thrombotic effects.

Risks of aspirin: Reye's syndrome, drug toxicity, anemia

alexandragillotte2023 — 2025-10-09 14:26:15 UTC

Among children hospitalized for croup, children who received >1 dose of dexamethasone had a longer LOS compared with children who received 1 dose of dexamethasone; however, there was no statistically significant difference in the 30‐day return to ED visits.

Consideration: dexamethasone dose should last around 24 hours.

Side effects of dex: hyperglycemia, irritability, difficulty sleeping, hypertension, (suppression of adrenals on prolong courses)

kimberlyohara1 — 2025-10-09 19:10:31 UTC

-Study of children presenting to ED with suspected CAP: Only 3 physical examination findings (wheezing, retractions, respiratory rate) had acceptable interrater reliability (IRR)

-Other examination findings that are typically considered important in making the clinical diagnosis of pneumonia (eg, crackles/rales and decreased breath sounds) demonstrated poor to moderate IRR.

Take home: Reliability of many exam findings in CAP is not great; but the fair reliability of wheezing, retractions, and RR must be considered in the clinical management and research of pediatric CAP.

Risk factors for severe disease among children hospitalized with RSV

2025-10-10 22:07:21 UTC

Retrospective cohort study that stratifies different risk factors in children of different age with severity of RSV-associated acute respiratory infections. I thought it was compelling that asthma and neurodevelopmental disease were associated with increased risk of severe disease.

kimberlyohara1 — 2025-10-12 22:27:35 UTC

PediactricsInReview is a great resource!

ESR: rises within 1-2 days, normalizes over weeks

CRP: rises within 4-6 hours, peaks in 2 days, normalizes within 7-10 days. Also check units as different hospitals use different units.

PCT: rises within 2-3 hours, peaks in 1-2 days, normalizes in 2-3 days; >0.5 ng/mL may indicate bacterial infection

kimberlyohara1 — 2025-10-15 14:52:17 UTC

NORD: https://nordsummit.org/?utm_source=RareDiseases.org+Homepage+Banner&utm_medium=banner&utm_campaign=nord_summit_2025&utm_id=NORD+Summit+2025