https://padlet.com/aman156/1z6w8fkttreq en-us 2018-10-01 12:41:44 UTC 2024-11-20 11:07:30 UTC hello@padlet.com aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/288896572 Curly hair is a normal trait in many dogs including water dogs, terriers, spaniels and poodles. Poodles hair does not even shed and unless cut will continue to grow forever.]]> 2018-10-03 21:20:31 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/288896572 aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/288898263 The effected protein is keratin71 for curly hair. Keratin71 is made only in the tiny hair follicles. These proteins normally link together to form a sort of web inside cells. This web supports the curly hair structure. ]]> 2018-10-03 21:28:17 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/288898263 aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/288898965 The two base substitution in the keratin71 gene changes a single amino acid. This amino acid makes a remarkably different change in the shape of the protein. The keratin proteins in the hair are not strong enough to link together which would make them straight. This causes the hair to curl. ]]> 2018-10-03 21:31:45 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/288898965 aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/289396085 We see many examples of this in other animals. Vertebrates have many different types of keratin. The proteins build hair, nail and skin. They also build scales, feathers, shells, beaks and claws. Mice that are missing their keratin71 have curled whiskers and kinked fur. They also are missing patches of fur sometimes. When it occurs in people, they have wool-like and easily lose-able hair. ]]> 2018-10-04 21:15:21 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/289396085 aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/289400236 This is considered a variation. This is because there are no health problems associated with it and may even be beneficial to dogs when retrieving things from the water. Likely also effected by variation is differences in human hair follicle keratin. ]]> 2018-10-04 21:34:32 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/289400236 aman156 https://padlet.com/aman156/1z6w8fkttreq/wish/289401444 2018-10-04 21:40:56 UTC https://padlet.com/aman156/1z6w8fkttreq/wish/289401444