Synaptic Transmission by https://padlet.com/sanromancellbiology/synaptictransmission Share key points for each of the learning objectives en-us 2024-10-30 01:59:17 UTC 2024-11-01 14:16:01 UTC hello@padlet.com https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755732 Electrical fast- connecting cells (gap junction)

Chemical slow- need to cross synaptic cleft

]]> 2024-11-01 14:10:23 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755732 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755750 Electrical is through gap junctions while chemical is through synapses

]]> 2024-11-01 14:10:24 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755750 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755976 Electrical: fast, uses connexins and gap junctions. Chemical: slow transmission, examples: ionotropic/metabotropic.

]]> 2024-11-01 14:10:34 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197755976 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197756980 BZD binding site and barbiturates

]]> 2024-11-01 14:11:27 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197756980 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757216 Benzodiazepine receptor

]]> 2024-11-01 14:11:38 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757216 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757278 BZD, Flumazenil, and ethanol all have binding sites. Flumazenil will reverse BZD

]]> 2024-11-01 14:11:41 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757278 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757538 GABA is an inhibitory neurotransmitter

benzodiazepine binding site inhibits anxiety and stress

]]> 2024-11-01 14:11:59 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757538 LO3 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757832 I need more AMPA receptors :(

]]> 2024-11-01 14:12:18 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197757832 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759070 Parkinson’s disease

Degradation of neurons in substantia nigra 

Less dopamine receptors

Tremors.

Dementia with Lewy bodies

Buildup of proteins affect dopamine transmission.

Visual hallucinations


]]> 2024-11-01 14:13:34 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759070 Substantia nigra is the Kim Kardashian of dopamine production https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759238 2024-11-01 14:13:44 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759238 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759418 Dopamine has to do with PD Dementia (lewy body). Hallucinations are special for dementia. Dopamine is important for movement initiation and termination.

]]> 2024-11-01 14:13:55 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197759418 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197760023 Alzheimers ACh

]]> 2024-11-01 14:14:30 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197760023 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197760044 Amyloid plaques

]]> 2024-11-01 14:14:31 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197760044 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761054 Alzheimer’s- tau tangles and beta amyloid plaques!

]]> 2024-11-01 14:15:26 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761054 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761171 GBS- rapidly damaged peripheral neurons

]]> 2024-11-01 14:15:32 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761171 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761192 Lambert Eaton and lung cancer

]]> 2024-11-01 14:15:32 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761192 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761388 Inverted Champagne bottle

]]> 2024-11-01 14:15:38 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761388 CMTD https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761685 2nd decade of life

]]> 2024-11-01 14:15:50 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761685 Lambert Eaton https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761874 Smoking history (exposed to smoke)

usually presents with dry mouth, and may have small cell lung cancer. Parasthesia usually starts in the lower extremities and works it's way up

]]> 2024-11-01 14:16:00 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761874 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761905 CMT has high arch in foot and champagne bottle appearance in the lower leg

]]> 2024-11-01 14:16:02 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761905 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761920 GBS: attack on myelin sheath in the periphery. More likely when exposed to viruses like COVID and ZIKA.

]]> 2024-11-01 14:16:03 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197761920 https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197762156 CMT- X-linked

]]> 2024-11-01 14:16:14 UTC https://padlet.com/sanromancellbiology/synaptictransmission/wish/3197762156