https://padlet.com/133551/10ehtd3m97oy A rare inherited disease en-us 2019-03-13 18:29:06 UTC 2023-03-24 04:54:40 UTC hello@padlet.com https://padlet-assets.s3.amazonaws.com/icons/Removelove.png 133551 https://padlet.com/133551/10ehtd3m97oy/wish/342534705 Thalassemia is a inherited blood disorder that makes the body form an unusual amount of hemoglobin. Hemoglobin is the protein in red blood and it carries oxygen. If you have Beta Thalassemia major then you will have more severe symptoms and you will probably need blood transfusions every four to six weeks because red blood cells only live for around three months. ]]> 2019-03-18 17:47:45 UTC https://padlet.com/133551/10ehtd3m97oy/wish/342534705 133551 https://padlet.com/133551/10ehtd3m97oy/wish/342549894 Thalassemia disrupts normal production of hemoglobin and healthy red blood cells which causes anemia. Anemia is when your body doesn't have enough red blood cells]]> 2019-03-18 18:15:22 UTC https://padlet.com/133551/10ehtd3m97oy/wish/342549894 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343013342 2019-03-19 18:06:16 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343013342 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343014718 People with Thalassemia will have deformities in their skull and face. they will also have pale or yellow skin. Thalassemia is a blood disorder and will generally affect the heart, liver, and endocrine system the most. The symptoms of Thalassemia are fatigue, weakness, slow growth, abdominal swelling, and dark urine. ]]> 2019-03-19 18:08:28 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343014718 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343473208 Thalassemia is a very rare and there are only 200,000 U.S cases per year. You can be at greater risk for Thalassemia if you have family history of the disease. Thalassemia mainly affects Asians, Northern European, and Filipino people more]]> 2019-03-20 17:59:06 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343473208 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343478660 Thalassemia is diagnosed by blood tests including Complete Blood Counts  and Hemoglobin tests. For a diagnosis a person may need to get a blood sample taken so that the types of hemoglobin in there blood can be measured]]> 2019-03-20 18:09:25 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343478660 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343483108 Thalassemia is treated through blood transfusions, iron chelation therapy, and folic supplements. Medications for the disorder are only available if you have a less severe case of Thalassemia the medications are called Ferriprox and Deferasirox. If you have a more severe case of Thalassemia then you will need blood transfusions. Recently gene therapy for Thalassemia which isn't used often had to clinical trials and it has shown significant improvement in the patients outcome. ]]> 2019-03-20 18:17:35 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343483108 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343566630 With Thalassemia the body forms an abnormal amount of hemoglobin (which is the protein found in red blood cells) the disorder results in large numbers of red blood cells being destroyed which leads to anemia.]]> 2019-03-20 22:35:03 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343566630 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343569832 2019-03-20 22:48:08 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343569832 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343577411 In alpha Thalassemia two genes of the same chromosomes. But Thalassemia is a mutation that causes shortage of red blood cells and can cause many health problems. ]]> 2019-03-20 23:30:41 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343577411 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343579347 In Thalassemia chromosome eleven is affected globin is is made on it and if one or both genes that tells chromosome eleven to make beta globin is altered then less beta globin is made.]]> 2019-03-20 23:41:43 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343579347 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343580475 The protein is hemoglobin the HBB gene encodes an important blood protein called beta globin the person who carries Thalassemia carries a mutation in both copies of the HBB gene. ]]> 2019-03-20 23:49:40 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343580475 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343582417 Normal Hemoglobin functions by binding and transporting oxygen from the capillaries in the lungs of all tissues in the body. High Hemoglobin can cause a rare blood disease. Low hemoglobin can cause anemia]]> 2019-03-21 00:01:55 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343582417 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343585318 Iron Deficiency Anemia]]> 2019-03-21 00:20:05 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343585318 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343596954 Beta Thalassemia cells iron deficiency]]> 2019-03-21 01:20:44 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343596954 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343597208 Mother and Father being carriers of the trait and passing it on to their kids]]> 2019-03-21 01:21:59 UTC https://padlet.com/133551/10ehtd3m97oy/wish/343597208 133551 https://padlet.com/133551/10ehtd3m97oy/wish/343598664

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