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Alstrom syndrome is extremely rare and incredibly devastating disorder that cannot be cured. it dates back to 1959 and still carries on today, however research is being done on this awful syndrome.

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Antibiotics
Oral diabetes medications
Meglitinides
Injected diabetes medicine
Pramlinitide
Xenatide
Cholesterol-lowering medications
Heart medications

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Corrective lenses
Special education
Hearing aids
Healthy diet
Physical activity
Dialysis
Transplantation
Surgery

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It was first described by Carl-Henry Alström

in Sweden in 1959. Thus the name Alstrom syndrome.

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alstrom syndrome (disease or medical condition)

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Alström syndrome is characterized by a progressive loss of vision and hearing, a form of heart disease that enlarges and weakens the heart muscle (dilated cardiomyopathy), obesity, type 2 diabetes mellitus (the most common form of diabetes), and short stature. This disorder can also cause serious or life-threatening medical problems involving the liver, kidneys, bladder, and lungs.

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The likelihood of having a child who is only a carrier of the gene is 50% with each pregnancy. The likelihood of a child receiving normal genes from both parents and being considered to be genetically normal is 25%.

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The type of gene is a rare autosmalrecessive disease characterized by multiorgan dysfunction.

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November 21, 2014: Alström syndrome is a rare autosomal recessive disease characterized by multiorgan dysfunction. The key features are childhood obesity, blindness due to congenital retinal dystrophy, and sensorineural hearing loss. Associated endocrinologic features include hyperinsulinemia, early-onset type 2 diabetes, and hypertriglyceridemia. Thus, AS shares several features with the common metabolic syndrome, namely obesity, hyperinsulinemia, and hypertriglyceridemia.

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It is among the rarest genetic disorders in the world, as currently it has only 266 reported cases in medical literature and over 501 known cases in 47 countries.

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Vision loss
Hearing loss
Obesity
Heart enlargement
Type 2 diabetes
Scoliosis
High blood pressure
Liver and kidney issues
Learning disabilities

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This syndrome is a rare genetic disorder caused by mutations in the gene ALSM1.