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What is Sickle Cell Anemia? www.fudgefoundation.com

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What is Sickle Cell Anemia? Learn what causes Sickle Cell Anemia and donate to www.fudgefoundation.com today. Let's find a cure for Sickle Cell together.

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1) Researchers separate the cells from blood samples from patients that have SCD and patients that don't have SCD.
2) RBC in people that have SCD look like sickles since they have no oxygen.
3)Sickled blood cells go to areas of the body with more oxygen.
4)As the cells circulate the body they become more rigid.
(Urban Health)

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SIckle Cell Disease Association of America - Baltimore, Maryland
Office 410.528.1555 Fax 410.528.1495 Toll Free 800.421.8453 Monday - Friday: 9:00am - 5:00pm (EST)

Email: scdaa@www.sicklecelldisease.org

Sickle Cell Disease Foundation of California - Ontario, California
3602 Inland Empire Blvd, Suite B220
Ontario, CA 91764
Phone (909) 743-5226 or (310) 693-0247
Toll Free (866) 288-CURE (2873)
Fax (909) 948-9345
email: info@scdfc.org

Sickle Cell Society - London, England
54 Station Road

London

NW10 4UA

020 8961 7795

020 8961 8346

info@sicklecellsociety.org

Children's Sickle Cell Foundation- Pittsburgh, Pennsylvania
412-431-5214
support@cscfkids.org

Children’s Sickle Cell Foundation, Inc.
Gove Business Center
226 Paul St., Suite 105
Pittsburgh, PA 15211

Piedmont Health Services and Sickle Cell Agency

1102 East Market Street

Greensboro, NC 27401 USA

Phone: (336) 274-1507

Toll-free: (800) 733-8297

Email: scdap@scdap.org

Website: http://www.piedmonthealthservices.org/index.html

Sickle Cell Association of Ontario

3199 Bathurst Street Suite 202

Ontario, M6A 2B2 Canada

Phone: (416) 789-2855

Email: sicklecell@look.ca

Website: http://www.sicklecellontario.org/

Sickle Cell Awareness Group of Ontario

1280 Finch Ave W, Suite 517

Ontario, M9M 2Z3 Canada

Phone: (416) 745-4267

Email: info@sicklecellanemia.ca

Website: http://sicklecellanemia.ca/index.php

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The only cure to this day for SCD is bone marrow transplant. In this transplant they take the healthy RBC from the donor's bone marrow and transfer it to the patient's bone marrow.

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Hemoglobin SC (usually mild)

Hemoglobin Sβ thalassemia

Less Common

Hemoglobin SD

Hemoglobin SE

Hemoglobin SO

(WebMD)

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It's a disorder in the Hemoglobin-beta gene found on chromosome #11. It is a genetic condition that is present at birth, when a child receives two sickle genes, one from each parent.

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Antibiotics
Blood transfusion
Pain relieving medicines

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42 for males
48 for females
(NCBI)

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1/365 African Americans
1/16,300 Hispanics
1/13 Africans
Total of 100 million people worldwide have the disease
(Medline Plus, and National Heart, Lung, and Blood Institution

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Tiredness/Weakness
Shortness of breath
Dizziness
Headaches/Migraines
Coldness in hands/feet
Swollen hands/feet
Jaundice
Organ damage
Delay growth

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1/4 chance of Maria being a homozygous recessive individual.

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Autosomal Recessive Trait

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When someone has abnormal shaped hemoglobin. Hemoglobin is a molecule that carries oxygen through the body. When one has abnormally shaped hemoglobin clumps start occurring in the blood stream due to the odd shape of the cell. Since the sickle cells don't live for a long period of time, it causes a shortage of red blood cells.