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In Oryx and Crake,  a pharmaceutical company called HelthWyzer creates pandemics throughout the world in order to make money off of the vaccines they sell. In our world there is controversy on whether the COVID-19 pandemic is a natural virus or if it was man made by China.

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As a result of global warming in the world of Oryx and Crake, it is warm all year round and sea level has risen to the point where all of the east coast of north America has been flooded. Parallels to our world are not difficult to draw with it getting hotter each year and the ice caps melting more and more by the day.

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In Oryx and Crake, The people are split between the compounds and the pleeblands. The former being for the rich and wealthy and the latter being for the poverty stricken. This dynamic isn't very uncommon throughout the world. Many 2 and 3 worlds countries are split between the rich living in their ivory towers and everyone else struggling to feed themselves each day.

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Environmental destruction in favor of money making

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Environmental destruction in favor of money making

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In Oryx and Crake, a coffee company nukes forests to have more area to plant coffee beans.  In real world Brazil, rainforests are being burned down to create for farmland.

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In Oryx and Crake, The character Oryx is a child who falls victim to human trafficking and is sold to America as a sex slave. In the real world there are around 40.3 million human trafficking victims worldwide. For example Jeffrey Epstein's notorious sex trafficking ring involving celebrities like Prince Andrews.

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Xenotransplantation is the process of mixing human DNA with animal organs in order to make them usable for humans. In Oryx and Crake they breed humans organs in pig like creatures called "Pigoons". In the real world research has started to find a way to create human organs in pigs to solve the human organ transplant crisis.