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A disorder in which the adrenal glands don't produce enough hormones. Specifically, the adrenal glands produce insufficient amounts of the hormone cortisol and sometimes aldosterone, too. When the body is under stress, this deficiency of cortisol can result in a life threatening Addisonian crisis characterized by low blood pressure. John F. Kennedy was affected with Addison's Disease.

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A condition that occurs from exposure to high cortisol levels for a long time. The most common cause is the use of steroid drugs, but it can also occur from overproduction of cortisol by the adrenal glands. Signs are a fatty hump between the shoulders, a rounded face, and pink or purple stretch marks. Ayesha Curry was affected with Cushing's Disease.

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An immune system disorder of the butterfly-shaped gland in the throat. The thyroid overproduces hormones. The condition is more common in women under age 40. Missy Elliot was affected with Grave's Disease.

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A disorder where the immune system attacks the butterfly-shaped gland in the neck. Initially, inflammation of the thyroid causes a leak resulting in excess thyroid hormones. Over time, the inflammation prevents the thyroid from producing enough hormones. Gina Rodriguez was affected with Hashimoto Disease.

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A serious condition that is nearly always caused by an adenoma, a tumor of the pituitary gland. Gigantism occurs in patients who had excessive growth hormone in childhood. The pituitary tumor cells secrete too much growth hormone, leading to many changes in the body. Sandy Allen was affected with Gigantism.

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A condition in which the pituitary gland does not make enough growth hormone. Dwarfism is generally defined as an adult height of four feet 10 inches or less. Common complications include bowing of the legs, hunching of the back, and crowded teeth. Ellie Simonds was affected with Dwarfism.

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It's caused by a hormone-secreting, noncancerous tumor on the pituitary gland. The hormone-producing gland in the brain overproduces prolactin. It also decreases the levels of some sex hormones. Tara Palmer-Tomkinson was affected with Prolactinoma.

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A cancer of the thyroid at the butterfly-shaped gland at the base of the neck. The cause of thyroid cancer is poorly understood. However, it was found that it may involve a combination of genetic and environmental factors. Kim Cattrall was affected with Thyroid Cancer.

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Abnormal enlargement of the butterfly-shaped gland below the Adam's apple. A goiter commonly develops as a result of iodine deficiency or inflammation of the thyroid gland. It can also occur in a gland that is producing too much hormones. Oprah Winfrey was affected with Goiter.

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A condition in which the thyroid gland doesn't produce enough thyroid hormone. Hypothyroidism's deficiency of thyroid hormones can disrupt such things as heart rate, body temperature, and all aspects of metabolism. Hypothyroidism is most prevalent in older women. Sofia Vergara was affected with Hypothyroidism.

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The overproduction of a hormone by the butterfly-shaped gland in the neck. It causes the gland to produce too much thyroxine hormone. It can also increase metabolism. Roger Ebert was affected with Hyperthyroidism.

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A chronic condition in which the pancreas produces little or no insulin. It typically appears in adolescence. This makes blood sugar levels very high and causes health problems. Halle Berry was affected with Diabetes Mellitus Type I.

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A chronic condition that affects the way the body processes blood sugar. With type 2 diabetes, the body either doesn't produce enough insulin, or it resists insulin. This causes blood glucose levels to rise higher than normal. Larry King was affected with Diabetes Mellitus Type II.

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A hormonal disorder causing enlarged ovaries with small cysts on the outer edges. The cause of polycystic ovary syndrome isn't well understood, but may involve a combination of genetic and environmental factors. They are also not harmful but lead to hormone imbalances. Jillian Michaels was affected with PCOS.