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1. Defibrinated plasma, in order to clot when mixed with tissue thromboplastin and calcium, requires an outside source of?
2.Aspirin ingestion has the following hemostatic effect in a normal person. In what way?
3. Which of the following is a source of error that can affect most coagulation procedures?

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1. In Mixing tests, how does Heparin affect the procedure?
2. aPTT: Prolonged aPTT means________
3.PT: what is the ISI value of the most sensitive thromboplastin reagent?

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aPTT test: Activated partial thromboplastin time is a routine hematolgical test that assess what?
PT test: Prothrombin time is an essential test for?
Mixing studies: Absorbed plasma is deficient in what factors?

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Mixing Test: What are the reagents used?

PT: True or False: Reference range is 10.0 – 14.0 seconds

aPTT: What causes a falsely long aPTT?

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1) In the mixing studies, plasma ( both adsorbed and aged) provides specific correction on coagulation factors, however What if serum will use in the test, what are the corrected and not corrected coagulation factors.

2)APTT uses activator cephalite, In PT test, what is/are the composition/s of the reagent?

3) What is the role of cephalite in the procedure of APTT?

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Madiano, Angelica

1. What is the essence of using cephalite in aPTT? What is cephalite?

2. In correction tests, why do we have to perform mixing test after performing aPTT/PT with prolonged results? Can we also use correction test when the results are below normal after performing aPTT/PT?

3. In PT, what does it indicates when the PT is below the normal range?

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1. Why is mixing test designed for the Investigation of prolonged PT AND aPTT?

2. Why do we need to use controls in Prothrombin time test?

3. What are the deficiencies in aPTT?

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1. It is the manner of reporting results for the Prothrombin Time (PT) test?

2. Mixing Test: What is/are the possible disease/s involve if the APTT is corrected by the absorbed plasma?

3. APTT is a Screening tests for Factors XII, XI, prekallikrein, HMWK, IX ,VIII X, V, II and I (Intrinsic & Common Pathway). if the:
PT is normal
APPT is prolonged
what specific factor is deficient?

a. factor VII
b. factor III
c. factor VIII

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Tayaban, Hannalou D.
PT:
1. Why is PT used to monitor warfarin therapy?
aPTT:
2. Why is aPTT used in monitoring unfractionated Heparin Therapy?
Mixing Studies:
3. No correction indicates a circulating inhibitor. How do we identify the specific inhibitor that is causing the problem?

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Raymundo, Janna Maen B.

1. In PT, what does it mean when the ISI is closer to the value of 1?

2. In APTT, is there a negative effect to the test when the reagent cephalite is not kept at room temperature?

3. Are mixing tests the only way to investigate PT and APTT prolongation?

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1.      Correction Test: In aged plasma, plasma is incubated for how long in what temperature?

2.      PT Test: What is the principle of PT?

3.      APTT: What conditions affect the aPTT value?

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Mixing test: What is the specimen of choice?

PT: Give some example of prolonged PT and what causes prothrombin?

aPTT: Why is aPTT used to monitor heparin?

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Mixing test: When do you do mixing test?

PT: How do coumarin derivatives work? How do they affect the PT?

aPTT: What are the factors measured by aPTT?

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Mixing Test: In fresh plasma, what coagulation factors are lacking?
PT: Why is prothrombin time used in monitoring a patient who is on warfarin therapy?
APTT: When is the time for clot formation in APTT?

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APTT: When should the timer (stopwatch) start while maintaining the tube at 37C water bath? When should it be stopped?

PT: In the prothrombin time test, what is/are the thromboplastin reagent used?

MIXING TEST: Mixing studies are performed for the prolonged clotting time only, if the result remains to be prolonged, what could be present that inhibits the test to be corrected upon the addition of the combination of NPP and patient's plasma?

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Cruz, Hallie Kate A.
Correction or Mixing Tests:
What are the indications in Correction or mixing tests if there is 1. Factor deficiency and 2. Circulating inhibitor?
Prothrombin Time Test:
What is the ISI value of the most sensitive Thromboplastin reagent, based on WHO standards?
APTT:
In performing this test, what should be added into the tube heated at 37 °C waterbath before you start timing for the APTT?

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1. What factors are deficient in the Absored plasma?
2.  (True of False): APTT is used for monitoring fractionated Heparin therapy
3. The most sensitive thromboplastin reagent have an ISI value of
a. 1.10
b. 1.00
c. 1.01

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Activated partial thromboplastin: What causes the falsely long aPTT?

Prothrombin time test: what is a prothrombin time test? Explain briefly.

Correlation or mixing test: What is the purpose of mixing test?

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PT: True or False: The closer the ISI to 1, the more sensitive the reagent is.
aPTT: Why is aPTT used in monitoring a patient who is on
heparin therapy?
Mixing studies: True or False: Mixing or Substitution studies determine the cause of prolongation in the secondary hemostasis.

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APTT: What is the use of a Citrated Partial Thromboplastin Time?

PT: Give atleast one sources of error in Prothrombin Time

Correction Test: Why does aged plasma used in hemophilia B?

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Mixing test: What is the most probable coagulation factor deficiency in corrected PT?

PT: What does prolonged PT indicates?

aPTT: State the factors affecting Falsely long aPTT.

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Kimayong, Apollo Josel D. 1.Correction/Mixing Test:  Why do we need to use a 1:1/50:50 ratio with the samples?                              2.PT Test:                             Why is PT used in monitoring a patient who is on warfarin/Coumadin therapy?                          3.APTT Test:                       What will happen if cephalite will not be placed at room temperature? How will it affect the result? 

# data[].attributes.subject
Kimayong, Apollo Josel D. 1.Correction/Mixing Test:  Why do we need to use a 1:1/50:50 ratio with the samples?                              2.PT Test:                             Why is PT used in monitoring a patient who is on warfarin/Coumadin therapy?                          3.APTT Test:                       What will happen if cephalite will not be placed at room temperature? How will it affect the result? 

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Simbillo, Melissa Jane C.
PT : How does warfarin affects the result of PT?
Corrected APTT: What are the possible deficiency factors can be detected ?
APTT: How does hemolysis affects the result of APTT

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1. Hemophilia B also know as Christmas disease is corrected by Absorbed plasma.

von Willebrand disease is corrected by Aged plasma.
A. Both statements are false.
B. First statement is true, second false
C. Both statements are true
D. First is false, second is true

2. What is the 3rd step in performing Prothrombin time test?

2. Give 2 sources of error in APTT

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APTT: What are the possible sources of error in doing this test?

PT: What are conditions that can be seen in prolonged PTT?

Correction/Mixing Test: Is vWD in APTT is corrected by aged plasma? True or False.

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1.Knowing the concepts of the three test, as a medical technology intern how can you make a solution or remedies when you acquired one of the sources of error when you are engaged in the situation?

2.Whats the difference and similarities of the two test PT (Prothrombin Time) and (APTT Activated Partial Thromboplastin Time).

3.What is the preferred color of tube used in PT and APTT?

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APTT: Give at least one (1) sources of errors in APTT
PT: What is the international sensitivity index for the thromboplastin reagent?
Mixing Tests: What is the most probable coagulation factor deficiency for PT and APTT?

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APTT: Give some condition/s in which the APTT is prolonged.

PT: Give some abnormal conditions wherein prothrombin time is prolonged.

Correction or MIxing Test: Give 1 advantage of using aged plasma as the reagent for the correction test.

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1. APTT: In prolong aPTT, what ae the acquire circulating inhibitors?

2. PT: [TRUE OR FALSE]
Factor activity of less than 26-28% is prolonged PT.

3. CORRECTON TEST: What are the coagulation factors deficient in aged plasma?

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1. What specimen or what is used in correcting hemophilia B or Christmas disease?
2. What is the cause of of Falsely short aPTT?
3. What test is used in screening factors VII,X,V,II and I or the extrinsic or common pathways?

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APTT: What is the use of cephalite?

PT: Why does samples need to be incubated?

CORRECTION TEST: Why is absorbed plasma used?

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PT
1. PT detects the deficiencies in what factors?

2.  What factors are inhibited by oral anticoagulant?

3. Give at least 3 conditions are seen in prolonged PT.

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1.What does “No correction” on mixing study imply?
2.Why is PROTHROMBIN TIME EMPLOYED IN MONTORING A PATIENTS WHO IS ON A WARFARIN THERAPY?
3. Activated partial thromboplastin time is a routine hematological test that assesses what coagulation pathway?

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Mixing studies:  Give at least 3 reasons as to why Mixing tests is done.

APTT: Why is APTT used for monitoring unfractioned Heparin therapy?

PT: Why is Prothrombin Time an essential test for extrinsic and common pathway?

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Raquel Awidan
1. What does partial or no correction indicate in mixing studies?
2. Why is there a need to incubate the PT reagent in the PT Test?
3. Why is APTT used in monitoring unfractionated Heparin therapy?

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1. In correction studies, why do we need to record the correction of PT for each mix?

2. What does it indicate if the PT is shortened?

3. Why is there a need to process the control sample after the steps in APTT test is completed?

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Sibayan, Shyde C.
Correction Tests: Give (2) importance of performing the mixing or correction test.

PTT: What anticoagulant is the PTT specific for?

APTT: How is APTT related to heparin therapy?

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Saragosala, Raynell S.
MIXING TEST
1.) Is there a need to conduct a Mixing test even if the result of Prothrombin time is normal while the Activated Partial Thromboplastin time is prolonged?
a.) Yes, because APTT needs to be corrected.
b.) No, because PT is already normal.
c.) Yes, because PT is already normal.
d.) No, because i don't know.
e.) None of the above

Prothrombin Time
2.) In the International Sensitivity Index (ISI) what is the value of the most sensitive thrmoboplastin reagent, based on WHO standards
a.) 2.00
b.) 10.00
c.) 1.00
d.) 1.69
e.) None of the above

Activated Partial Thromboplastin Time
3.) All but one.
Acquired Circulatory Inhibitor
a.) Heparin
b.) Lupus
c.) Calcium
d.) Antibody to a specific factor
e.) None of the above

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APTT: What causes a high aPTT?
PT: Why prothrombin time test is done?
Mixing Test: Explain the principle of Mixing Test.

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Correction/mixing studies: What are the limitations of the test procedure?

APTT: Why is APTT employed in monitoring patient who is on heparin therapy?

PT: How is the Prothrombin time of patients on anticoagulant therapy reported?

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MIXING TEST
What does this indicate:
a. Clotting time remains prolonged
b. Clotting times remains normal or decreased to near normal

PROTHROMBIN TIME
What is the clinical significance of Prothrombin Time?

APTT
Give criteria for rejecting samples used in APTT.

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Alvarez, Bryn Elizabeth E.

1. PT: What is the major use of Prothrombin Time Test?

2. aPTT: What factors are not measured in aPTT?

3. Mixing test: When do you do mixing test?

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1. Mixing Studies: In the presence of True factor deficiency what should be the the result of mixing studies. 2. PT: Is Pt a primary or secondary Hemostasis Test? 3. aPPT: What are the sources of error for prolonged aPPT?

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1. Mixing Tests: What Coagulation factors can be found in aged plasma?
2. PT:  What does prolonged PT may indicate?
3. APTT: APTT test is a screening test for what factors? Group the factors according to their corresponding pathways.

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Yusingco, Hannah Nicole Aubrey P.
1. Mixing studies: The shortening of time into the reference range indicates what?
2. Prothrombin Time Test is used in screening what factors?
3. What does APTT monitors?

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1. In correction or mixing studies, why aged plasma needs to be incubated at 37 degree Celsius for 2-3 days?
2. In aPTT, why is this test used in monitoring unfractionated heparin therapy?
3. In PT test,  why is this test used in monitoring warfarin therapy?

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PERIA, CHESKA SHANEAJ M.

ACTIVATEDPARTIAL THROMBOPLASTIN  TIME :
1.TRUE OR FALSE : When performing APTT,  It could be a possible source of error the preparation, and inherent patient problems.                                                                                                                                         CORRECTION OR MIXING TESTS :                                                                     2. It is  absorbed with aluminum hydroxide  and it lacks  FII, FVII, FIX & FX

PROTHROMBIN TIME TEST :                                                                               3. What can be the indication when prolonged Prothrombin Time test happened?

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Correction or Mixing Test

____________1. It is incubated  at 37 for 2-3 days

Prothrombin time test
____________2. T/F Prothtombin is a screening test for factors VII, X, III, I

Activated Partial Thromboplastin Time
____________3.T/F aPTT is a screening test for Factors XII,, perkalikrein, HMWK, IX, VIII, V, II, I, XI

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UBERA, ALFREDO JR. D

1.  In mixing studies, what does Partial or no correction indicate?

2. What are some sources of error in the Prothrombin Time Test?

3. What Therapy does APTT monitor?

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Neil Deo Serafica
APTT: Why is there a need to incubate CaCl2 before adding it to the reaction tube?
PT test: What are some sensitive thromboplastin reagents used in prothrombin time test?
Mixing Tests: What does it mean if the correction tests did not shorten/correct the prolonged APTT or PT results?