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Here I have a briefing material for the Prof Exam I wish All the best.

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Here I have a briefing material for the Prof Exam I wish All the best.

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PS: I welcome Questions, comments and interactions through this Padlet wall

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Application of these ligand-receptor knowledge will be in phamacology

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Application of these ligand-receptor knowledge will be in phamacology

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Think about "stimulating" or "inhibiting" those receptors

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Autonomic Nervous System (ANS) include Cholinergic and Adrenergic system 

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Autonomic Nervous System (ANS) include Cholinergic and Adrenergic system 

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Think about "Adrenergic" receptor

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Pharmacology - ADRENERGIC RECEPTORS & AGONISTS (MADE EASY)

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In Musculoskeletal contraction, involves SOMATIC or Voluntary nervous system. We can extend further our understanding about Nerve which use Acetylcholine to the Autonomic Nervous system 

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In Musculoskeletal contraction, involves SOMATIC or Voluntary nervous system. We can extend further our understanding about Nerve which use Acetylcholine to the Autonomic Nervous system 

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Can you describe the TWO divisions of AUTONOMIC nervous system ?

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Pharmacology - CHOLINERGIC DRUGS (MADE EASY)

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At molecular level there are ligand and its receptor(s) interacting leading to physiological outcome

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At molecular level there are ligand and its receptor(s) interacting leading to physiological outcome

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For skeletal muscle contraction there is Acetylcholine (Ligand). How many Acetylcholine receptors are there?

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Now think about Ouabain. Name the transporter which this cardiac glycoside acts on 

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Now think about Ouabain. Name the transporter which this cardiac glycoside acts on 

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Dear all, Phase 1 aims at preparation towards a "ready" candidate to face clin years. So Its more of output/application of what we have learnt in Yrs 1 and 2

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Dear all, Phase 1 aims at preparation towards a "ready" candidate to face clin years. So Its more of output/application of what we have learnt in Yrs 1 and 2

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Recall the cell transport lecture....Think Digitalis

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Video on Digitalis to be used in a class on pharmaceutics in the TV broadcast of "Universiteit van Nederland"

"Digitalis works by inhibiting sodium-potassium ATPase. This results in an increased intracellular concentration of sodium ions and thus a decreased concentration gradient across the cell membrane. This increase in intracellular sodium causes the Na/Ca exchanger to reverse potential, i.e., transition from pumping sodium into the cell in exchange for pumping calcium out of the cell, to pumping sodium out of the cell in exchange for pumping calcium into the cell. This leads to an increase in cytoplasmic calcium concentration, which improves cardiac contractility." Digitalis on Wikipedia

Client:
Adam Cohen
CHDR
www.chdr.nl