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Is there a natural way to intake leptin rather than having injections from a doctor?

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Can leptin be found in certain foods naturally? Or can certain foods be modified to contain the hormone?

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I know that all three of these have the ability to make individuals more/less predisposed to gaining weight, but are the three interconnected?

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Because a lack of leptin can cause you to eat more, would this increase your risk of developing type 2 diabetes? Is there a link between the two?

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Coffee is often thought to be an appetite suppressant. Is this true and if so, how does this relate to Leptin production?

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The video mentioned that other genes and hormones can affect obesity. What are some of these other genes and how do they affect a person’s weight differently then Leptin and the MC4R receptor might?

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The documentary said that other genes are being found that also affect obesity. Which genes/hormones are these?

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Do thyroids and your leptin connect in any way? Do thyroids and your pancreas connect?

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1. Can chewing gum affect leptin level/role? I typically get hungry after chewing gum, and I wonder if gum 'tricks' the brain into thinking I have eaten food.
2. If 1/1000 people have the MC4 mutation, but well over 0.001% of America is obese, is there a different disorder/mutation (other than excessive eating) that forces people to become obese?

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1. What is the standard size of someone’s weight range?

2. What determines what someone’s weight range is besides leptin or MC4?

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How does the knowledge of leptin contribute to the existing hypotheses?

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The video looked like it was from 20 years ago, I would be surprised if all of the statements they made remain true today.

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Are people's body types decided mainly by genetics or by their level of activity/diet? I've heard both can be true in the past, but is there one that plays a bigger factor in body type?

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1. If one parent of an individual has a mutation in the MC4 Receptor while their other parent does not, will the child also have this mutation or will their receptors develop normally? How do we know?

2.Why is Leptin produced in the fat cells and why does this hormone stay in the blood stream?

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Let's say a person has a parent/grandparent that is very overweight but they themselves are very active and eat healthy, so they lost a lot of weight later in their life. If they have the same genetic makeup in terms of leptin and insulin ect. of both the parents and the grandparents, would the next generation be born overweight or not?

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1/1000 people have MC4 reception disorders, but over 30% of the US Population is obese. Should we focus more on the socio-economic and cultural factors, or the scientific, genetic ones? Which is an easier fix? Which affects more people?

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The video seemed to suggest that people with the same genetic defect as the woman being studied become obese because they overeat and consume too many calories. However, if the hormone hypothesis is correct and the biggest factor in weight gain is actually glucose intake, could people with leptin resistance eat as much as they want while cutting out carbohydrates and still lose weight?

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Why is leptin such an uncommon thing. In the video it sounded like it would save a lot of people from over eating but then it said that it didn't work very well in humans...why?

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Why wasn't leptin discussed in the article? Is its discovery still relatively unknown?

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Have scientists been able to have another case like the one in the video? If not how were they able to create their conclusion with only one case on humans and the others on mice?

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Why did injecting Leptin not work

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Have scientists found anymore genetic mutations that have reportedly been directly correlated with obesity?

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Have there been any recent modifications in leptin injections? If so, have they shown significant weight loss for patients with MC4 reception disorders?

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Is there a hormone that has the opposite function of leptin and tells your body it needs to eat more?

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Do you have more similar weight characteristics to the parent is your same gender?

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Are there any statistics that show how many kids have the same body type as there parents?

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How come so many people are still unaware of the role of genetics in determining a person's body weight, especially given that obesity is such a relevant topic in the United States?

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Has the experiment been completed yet, and if so, what are its results?

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Are the two theories highlighted in the reading plus leptin the only possible causes for weight gain and obesity? Is it possible for more than one theory to be correct ex: (both calorie amount and insulin level influence weight gain)? How does the human microbiome factor into this?

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Is metabolism determined  by genetics?