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There is a lot of controversy surrounding certain vaccines as many believe it can cause other health defects. e.g. many people believe that the MMR vaccine causes autism in children and therefore resist the vaccination.

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People without a fully-working immune system, including those without a working spleen

People on chemotherapy treatment whose immune system is weakened

People with HIV

Newborn babies who are too young to be vaccinated

Elderly people

Many of those who are very ill in hospital

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When a high percentage of the population is vaccinated, it is difficult for infectious diseases to spread, because there are not many people who can be infected. For example, if someone with measles is surrounded by people who are vaccinated against measles, the disease cannot easily be passed on to anyone, and it will quickly disappear again

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Vaccinated vs unvaccinated

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by vaccinating even people who cannot be vaccinated can be protected.

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The level of vaccination needed to achieve herd immunity varies by disease"

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The resistance to the spread of a contagious disease within a population that results if a sufficiently high proportion of individuals are immune to the disease, especially through vaccination.

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When nobody is immuniszed, disease spreads through the population. When some of the population are immunized, disease spreads through some of the population. When most of the population are immunized, the spread of the disease is constrained.