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Overview: Aspirin is used to treat pain and fever. Common side effects can include an upset stomach or heartburn. Serious side effects are less common but may include allergic reactions or stomach bleeding. Tell your health care provider right away if you have stomach pain that will not go away, vomit blood, or notice blood in your poop. Aspirin is available in many forms, including tablets that are chewed, swallowed, or dissolved in water to drink. Some aspirin products also contain antacids to be gentler on the stomach.

What is aspirin used for?

Aspirin is commonly used for the following.

Aspirin may also be used for other conditions as determined by your health care provider.

How does aspirin work (mechanism of action)?

Aspirin works by blocking certain substances in the body that cause pain, inflammation, and fever.

How is aspirin supplied (dosage forms)?

Brands and other names

Dosage forms and strengths

81 mg chewable tablets

81 mg, 325 mg oral capsules

81 mg, 325 mg delayed-release oral tablets

81 mg, 325 mg, 500 mg oral tablets

300 mg rectal suppositories

325 mg effervescent tablets

How should I store aspirin?

Tablets and Capsules. Aspirin tablets and capsules should be stored at room temperature. Some products may also have directions on them to avoid exposing them to excessive heat, such as temperatures over 104 F (40 C). Follow the instructions on the product you have. Ask your pharmacist if you have any questions about how to store your medicine.

Rectal Suppositories. Aspirin suppositories should be stored in the refrigerator or a cool area, between 46 F and 59 F (8 C and 15 C).

What are the most common side effects of aspirin?

The most common side effects of aspirin are listed below. Tell your health care provider if you have any of these side effects that bother you.

There may be other side effects of aspirin that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of aspirin?

While less common, the most serious side effects of aspirin are described below, along with what to do if they happen.

Breathing problems or wheezing

Racing heart

Fever or general ill feeling

Swelling of the face, lips, mouth, tongue, or throat

Trouble swallowing or throat tightness

Itching, skin rash, or bumps on the skin called that can be red, pink, white, or brown, depending on your skin tone

Nausea or vomiting

Dizziness, feeling lightheaded, or fainting

Stomach cramps

Who should not use aspirin?

Allergies to Ingredients. People who are allergic to any of the following should not use aspirin.

Any other medicine known as a pain reliever or fever reducer

Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific aspirin products they stock.

Mouth or Tonsil Surgery. You should not take aspirin for at least seven days after having surgery in your mouth or your tonsils taken out, unless your health care provider tells you to.

What should I know about aspirin before using it?

Taking aspirin with food or with a full glass of water may reduce your risk of having stomach-related side effects. Talk to your health care provider if you have concerns.

Keep aspirin out of the reach of children.

Stop taking aspirin and call your health care provider if any of the following apply to you.

Your pain is getting worse or lasts longer than 10 days.

Your fever is getting worse or lasts longer than three days.

The painful area is red or swollen.

You have new symptoms since you started taking aspirin.

If you are using aspirin suppositories, you need to take the suppository out of the wrapper before inserting it into your rectum. Ask your health care provider if you are not sure how to use a suppository.

People who are 60 or older can be at greater risk of some side effects from aspirin. Talk to your health care provider about your risks if you are in this age group.

What should I tell my health care provider before using aspirin?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if aspirin is right for you.

In particular, make sure that you discuss any of the following.

Other Medicines and Supplements. Aspirin may interact with other medicines and supplements. Before taking aspirin, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Current and Past Health Conditions. Tell your health care provider if you have any of the following.

Pregnancy. Do not take aspirin at 20 weeks or later in pregnancy without talking to your health care provider. Taking aspirin during this time may cause harm to a fetus and complications during delivery. Tell your health care provider if you are pregnant or plan to become pregnant. Your health care provider will let you know if you should use aspirin while you are pregnant or trying to get pregnant.

Breastfeeding. Aspirin passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should stop breastfeeding or stop taking aspirin.

Does aspirin interact with foods or drinks?

There are no known interactions between aspirin and foods or drinks.

Drinking alcohol regularly may increase your risk of side effects with aspirin. It is best to limit the amount of alcohol you drink.

Does aspirin interact with other medicines (drug interactions)?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking aspirin.

A blood thinner, which is a medicine used to treat or prevent blood clots

A nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen, naproxen, and others, which is in many prescription and OTC products for pain, swelling, and fever

A corticosteroid, such as dexamethasone, methylprednisolone, or prednisone, which is a medicine for certain inflammatory conditions

A diuretic, also called a water pill, which is a medicine used to reduce edema (fluid retention) and blood pressure

A medicine for gout

A medicine for diabetes

A medicine for arthritis

This may not be a complete list of medicines that can interact with aspirin. Always check with your health care provider.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

What should I do if I accidentally use too much aspirin?

If you or someone else has used too much aspirin, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of aspirin?

Aspirin is meant to be used only when needed. Use it according to the product label. If you miss a scheduled dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and only take the next one. Do not take double or extra doses. Do not take more than is recommended on the product label.

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Aspirin (Bayer, Vazalore, and others): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

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Find patient medical information for Aspirin (Bayer, Vazalore, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

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What is it?

Triacetin (C9H14O6), also known as glyceryl triacetate, is pharmaceutical excipient used in manufacturing of capsules and tablets, and has been used as a humectant, plasticizer, and solvent. It is a liquid, and has been approved by the FDA as a food additive. Triacetin is a water-soluble short-chain triglyceride that may also have a role as a parenteral nutrient according to animal studies. It is also used in the perfume and cosmetic industries.

Triacetin is listed on the FDA Generally Regarded As Safe (GRAS) List. According to the FDA, triacetin has been found to be non-toxic in long-term feeding tests in rats at levels that were several orders of magnitude greater than those to which consumers are exposed. Additionally, in a toxicology report from 2002, triacetin and a group of related triglycerides did not represent a hazard to human health based on the anticipated daily intake of 7.8 mg/day/adult, and other available data. One case of skin toxicity (allergic contact eczema) due to industrial use in cigarette filter production has been reported.

There is no evidence in the available information on triacetin that demonstrates or suggests reasonable grounds to suspect a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future.

[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed March 19, 2012.

[2] FDA's SCOGS database; propylene glycol; SCOGS-Report Number: 30; http://www.fda.gov/Food/FoodIngredientsPackaging/GenerallyRecognizedasSafeGRAS/GRASSubstancesSCOGSDatabase/ucm261045.htm. Accessed March 19, 2012.

[3] [3]SIDS. Screening Information Data Set for High Production Volume Chemicals. (2005) p. 169 Triacetin. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f?./temp/~uyt6aD:1Accessed March 17, 2012

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Top Medications with this excipient

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Triacetin (Inactive Ingredient) - Drugs.com

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Triacetin (C9H14O6), also known as glyceryl triacetate, is pharmaceutical excipient used in manufacturing of capsules and tablets, and has been used as a humectant, plasticizer, and solvent. It is a liquid, and has been approved by the FDA as a food additive.

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Willow bark, the bark of several varieties of willow tree, has been used for centuries as a pain reliever. The active ingredient in the medicine made from willow bark is called salicin.

Some people use willow bark as an alternative to aspirin, particularly those that experience chronic headaches or back pain. Willow bark is also used in some products to aid weight loss.

It comes from the branches of 2- to 3-year-old willow trees. Willow trees and shrubs grow all over the world, except for Australia and Antarctica. The white willow and black willow are two of the most common willows that are used medicinally.

When taken in moderation, willow bark does not appear to have negative side effects. The salicin in willow bark converts to salicylic acid. Some believe that this makes it gentler on your stomach than lab-created aspirin. Too much willow bark, however, can cause stomach cramping and bleeding.

Capsules

Willow bark can be purchased from many drugstores and almost any health food store in a powdered, encapsulated form. The recommended dose for pain relief is 240 milligrams a day.

Bark

The active ingredient in willow bark is salicin, but the accompanying flavonoids and plant particles might be part of what make willow bark effective. For this reason, some people prefer to actually chew on the unprocessed bark of the willow tree. It is difficult to determine how much salicin you are getting from each piece of bark, so this method of consumption should be approached with caution.

Liquid

Willow bark can also be found in a distilled tincture form. Taking a drop or two per day for pain relief (up to 2 milliliters) can work as an anti-inflammatory and pain relief substitute for aspirin.

Tea

Some health food stores sell willow bark tea, advertising it as a pain reliever and anti-inflammatory. Steep willow bark tea for two to three minutes in hot water. When consuming willow bark in this form, it's hard to tell how much salicin you are getting in each serving of tea.

Topical

Willow bark can be used topically. Since it isn't absorbed digestively, topical willow bark is a good alternative for those who commonly experience stomach ulcers. However, topical use can be harsh and cause skin irritation.

When used on people with lower back pain, willow bark was found to be more effective than placebo in a recent herbal medicine review. Conclusive data that contrasts willow bark to traditional aspirin is needed. However, if you're looking for an alternative to aspirin, you could consider willow bark.

Willow bark can also be used to relieve menstrual cramps and bring down a fever. The salicin inside willow bark works the same way as aspirin, by reducing inflammation and pain as it enters your bloodstream. Because of the anti-inflammatory properties of willow bark, it may be especially effective in combatting joint pain as well.

There are some people who should not use willow bark. If you have an allergy to aspirin, it's possible to have a reaction to willow bark as well. Willow bark can also interact with certain medications, like blood thinners and beta-blockers.

Children and adolescents up to the age of 16 are generally discouraged from taking willow bark for any reason. This is because of the risk of Reye's syndrome, a rare condition that causes brain and liver damage. Pregnant and breast-feeding women are also discouraged from taking any medication that contains salicylates. People with gastric ulcers should be especially careful with willow bark, in the same way that they would be cautious with aspirin, because too much could cause stomach bleeding.

Even though it is used widely, very few clinical trials have been done to verify the effectiveness of willow bark. Preliminary studies do show that there are some health benefits, and that certain species of willow contain higher concentrations of salicin and flavonoids than others.

In the studies that have been done, the risks and side effect s seem fairly minimal. And there are centuries of study and use of aspirin, which gets its active ingredient from willow bark.

Willow bark has been shown to help relieve some mild discomforts. But more research is needed to fully understand how it differs from aspirin. While it may be an effective alternative to aspirin for some, talk to your doctor before choosing to take willow bark.

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Willow bark, the bark of several varieties of willow tree, has been used for centuries as a pain reliever. The active ingredient in the medicine made from willow bark is called salicin. Some people use willow bark as an alternative to aspirin, particularly those that experience chronic headaches or back pain.

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Uses

This medication is used on the skin to treat common skin and foot (plantar) warts. Salicylic acid helps cause the wart to gradually peel off. This medication is also used to help remove corns and calluses. This product should not be used on the face or on moles, birthmarks, warts with hair growing from them, or genital/anal warts.

Salicylic acid is a keratolytic. It belongs to the same class of drugs as aspirin ( salicylates). It works by increasing the amount of moisture in the skin and dissolving the substance that causes the skin cells to stick together. This makes it easier to shed the skin cells. Warts are caused by a virus. Salicylic acid does not affect the virus.

How to use Salicylic Acid Film-Forming Liquid With Applicator

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

This medication is for use on the skin only. To avoid irritation, do not let this medication come into contact with your eyes, nose, mouth, groin, or any broken skin. If you do get the medication in those areas, flush the area with cool water for 15 minutes. Wash hands after use.

First, soak the corn, callus, or wart in warm water for about 5 minutes to soften the treatment area. Dry thoroughly. Your doctor may direct you to use a pumice stone, callus file, or emery board to carefully remove the top dead layers of skin after soaking and before applying the medication. This dead skin removal is only to help the medication work better. Do not try to rub the wart or callus off.

If you are using a liquid/gel, apply a few drops or a thin coat of the medication to cover the entire wart, callus, or corn using the applicator if provided. Be careful to apply it only to the affected area and not the surrounding skin. Let dry for 5 minutes. Depending on the brand used, you may need to apply the medication twice with each treatment. Check your product package and follow the directions carefully. You may cover the area loosely with a bandage. Repeat this procedure 1 to 2 times daily for up to 2 weeks for corns and calluses and 12 weeks for warts or as directed by your doctor.

If you are using a medicated pad or bandage, you may need to cut the pad so that it covers the treatment area completely but does not touch the surrounding skin. Peel off the protective covering and place the patch/bandage over the area. Leave in place according to package directions. Remove and place a new patch/bandage as directed (usually every 8 to 48 hours depending on brand). Repeat this procedure for up to 2 weeks for corns and calluses and 12 weeks for warts.

Dosage is based on your medical condition, product type/brand, and response to treatment. Do not use large amounts, apply this medication more often, or use it for a longer period than directed. Your condition will not clear faster, but the chance for side effects may be increased.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

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This medication is used on the skin to treat common skin and foot (plantar) warts. Salicylic acid helps cause the wart to gradually peel off. This medication is also used to help remove corns and calluses. This product should not be used on the face or on moles, birthmarks, warts with hair growing from them, or genital/anal warts.

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How aspirin is made - production process, manufacture, history, used, parts, procedure, steps, product

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Aspirin is one of the safest and least expensive pain relievers on the marketplace. While other pain relievers were discovered and manufactured before aspirin, they only gained acceptance as over-the-counter drugs in Europe and the United States after aspirin’s success at the turn of the twentieth century.

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A synthetic material is a man-made fiber that is created in labratories.

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Pros of aspirin: relieve menstrual cramps and bring down fever, reduces pain and inflammation as it enters your bloodstream.
Cons of aspirin: adolescents up to the age of 16 are at risk of Reye’s syndrome(a rare condition that causes liver and brain damage), a risk of bleeding in the stomach, small intestine, and brain, and can cause asthma attacks in individuals.

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The bark from willow tree makes salicylic acid. It contains high levels of salicin. Some forms of willow bark are capsules, liquid, tea, and topical.

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A keratolytic that "increases the amount of moisture in the skin and dissolving the substance that causes the skin cells to stick together." Bark from willow trees are used to make salicylic acid.

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a salicylate and a nonsteroidal anti-inflammatory drug (NSAID). The weight of aspirin depends on weight, hardness, thickness,and size.

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Used as a humectant, plasticizer, and solvent, triacetin is a liquid triglyceride that may also have a role as a parenteral nutrient according to animal studies.