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The Plague began in the mid-1300's. It is not exactly confirmed where the first plague outbreak began, but it is believed it's first major hit was in China, India, Egypt, Persia, and Syria in 1345.
https://web.cn.edu/kwheeler/black_plague.html

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At first, many believed rats to be the sole cause of the plague.  Later on, it was discovered that rats did not play a big part as originally thought. Microscopic bacteria called Yersinia Pestis, which live on fleas, were the cause of the plague. The fleas that this bacteria lived on would feed on infected animals, and this increased the fatality of the Black Death.
https://www.cnn.com/2018/01/16/health/black-death-plague-spread-by-humans-intl/index.html

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There are three types of plague: Bubonic, Septicemic, and Pneumonic Plague.
-Bubonic Plague is mainly the growth of lymph nodes in various spots of the body.
-Septicemic Plague affects the heart and bloodstream, and was most fatal.
-Pneumonic Plague mainly affects the lungs.
https://www.medicinenet.com/plague_facts/article.htm

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-The symptoms of Bubonic Plague are enlarged, painful lymph nodes, often called bubo. It usually occurs in the groin, armpit, or neck, and it can get as big as an egg or apple. These lymph nodes can eventually burst and seep out blood, pus, and a foul smelling black liquid. Flu-like symptoms such as headache, fever, chills, and fatigue can also occur.
-Symptoms of Septicemic plague include chills, fever, abdominal pains, fatigue, and shock. Tissue bleeding could occur as well. Skin also turned black more often with this type of plague.
-Pneumonic Plague symptoms are coughing, shortness of breath, pains in the chest, vomiting, diarrhea, chills, fever, and nausea.
https://www.healthline.com/health/plague#symptoms

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While there is no cure for the Plague, doctors recommend very strong antibiotics such as Gentamicin, Doxycyline, Ciprofloxacin, and Levofloxacin. An infected person will need immediate hospital care.
https://www.mayoclinic.org/diseases-conditions/plague/diagnosis-treatment/drc-20351297

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How Many Died In the Middle Ages Because Of The Plague?

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How Many Died In the Middle Ages Because Of The Plague?

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It is not exactly identified how many deaths were caused by the plague, but the estimated amount is around 60 percent of Europe. Europe's population at the time was about 80 million people, so about 50 million of those people ended up dead because of the plague.
https://www.historytoday.com/ole-j-benedictow/black-death-greatest-catastrophe-ever

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The doctors that were assigned to deal with patients infected by the plague wore certain attire to avoid being infected. Their uniforms consisted of wearing a long gown coated in wax, full-length boots, leather gloves, and a hat. They also wore a mask with a long beak, and they filled it with herbs and spices. This would purify the air they inhaled when they dealt with sick people. They also carried a wooden stick to keep the ill away.
https://www.historyonthenet.com/the-stuarts-the-plague-doctor

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There were many coping mechanisms that people of the medieval ages used to cope with the intensity. Many lashed out at neighbors, and others believed they had to cleanse their cities and towns of the sinners causing God to punish them. Many people fled in fear, and thousands of Jews were killed between 1348-1349. There were also flagellants where upper-class men went from town to town either beating themselves or others with leather straps studded with sharp items.
https://www.history.com/topics/middle-ages/black-death

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What Did People Of The Medieval Ages Think Of The Plague?

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What Did People Of The Medieval Ages Think Of The Plague?

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During the time of the plague, many thought that the disease was God's way of punishing them for their sins such as fornication, blasphemy, greed, worldliness, and heresy.
https://www.history.com/topics/middle-ages/black-death

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The Plague got it is nickname "The Black Death" because of one of the many symptoms that occur. The tissue of an infected person began to bleed, causing the tissue to bleed out and die. The end result would be the black discoloration.
https://www.newscientist.com/article/mg17223184-000-did-bubonic-plague-really-cause-the-black-death/

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Unlike many other diseases that thrive in the cold, the plague did not. It flowed strongly during warmer seasons such as spring and summer, but died off almost completely during winter.

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As Italian Poet Giovanni Boccaccio once said, "... the mere touching of clothes appeared to itself to communicate the malady to the toucher." This shows just how strong the disease was. A simple touch could cause a healthy person to be bed-ridden or even dead in three to five days.
https://www.history.com/topics/middle-ages/black-death

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Throughout history there's been many outbreaks of the plague, but nothing has been able to stop it. There have been breaks in time where the plague did not present itself because quarantines were created, but it would occasionally pop up a few generations later. It would repeat this process often.
https://www.theweek.co.uk/76088/what-was-black-death-and-how-did-it-end