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Brand: Norvasc

Stock dosage: PO - 2.5mg, 5mg, 10mg

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Therapeutic: antihypertensives

Pharmacologic: calcium channel blockers

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Inhibits the transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction

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Alone or with other agents in the management of hypertension, angina pectoris, and vasospastic (Prinzmetal’s) angina

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Hypersensitivity

Systolic blood pressure <90 mm Hg.

Severe hepatic impairment

History of CHF

Aortic stenosis

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CNS: headache, dizziness, fatigue

CV: peripheral edema, bradycardia, hypotension, palpitations

GI: gingival hyperplasia, nausea

Derm: flushing

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Monitor blood pressure and pulse before therapy, during dose titration, and periodically during therapy.

Monitor ECG periodically during prolonged therapy

Monitor weight daily

Monitor I&O

Assess for signs of CHF

Assess location, duration, intensity, and precipitating factors of patient’s anginal pain

Encourage patient to avoid large amounts (6–8 glasses of grapefruit juice/day) during therapy.

Instruct patient to contact health care professional if heart rate is <50 bpm

Caution patient to change positions slowly to minimize orthostatic hypotension.

Instruct patient on concurrent nitrate or beta-blocker therapy to continue taking both medications as directed and to use SL nitroglycerin as needed or prescribed

Encourage patient to avoid driving or other activities requiring alertness until response to the medication is known since this medication may cause drowsiness or dizziness

Encourage patient to contact health care professional if chest pain does not improve or worsens after therapy, if it occurs with diaphoresis, if shortness of breath occurs, or if severe, persistent headache occur

Instruct patient to avoid concurrent use of alcohol or OTC medications, especially cold preparations, without consulting health care professional.

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Brand: Lopressor
Stock dosage:

PO - 25mg, 50mg, 100mg, 200mg, 450mg
IV: 5mg/5ml

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Therapeutic: antianginals, antihypertensives

Pharmacologic: beta blockers

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Blocks stimulation of β₁ adrenergic receptors but has little or no effect on β₂-receptors except in high doses

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Hypertension

Angina pectoris

Prevention of MI and decreased mortality in patients with recent MI

Management of stable, symptomatic (class II or III) heart failure due to ischemic, hypertensive or cardiomyopathic origin

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Decompensated CHF

Pulmonary edema

Cardiogenic shock

Bradycardia or heart block

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CNS: fatigue, weakness, anxiety, drowsiness, insomnia, mental status changes

EENT: blurred vision, stuffy nose

RESPIRATORY: bronchospasm, wheezing

CV: bradycardia, hypotension, peripheral vasoconstriction

GI: constipation, diarrhea, dry mouth, gastric pain, heartburn

GU: erectile dysfunction, decrease libido, urinary frequency

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Monitor vital signs and ECG every 5–15 min during and for several hours after parenteral administration. If heart rate <40 bpm, especially if cardiac output is also decreased, administer atropine 0.25–0.5 mg IV as ordered

Monitor weight daily

Monitor I & O

Assess frequency and characteristics of anginal attacks periodically during therapy

Provide health education that this medication should be taken with meals or directly after eating

Caution patient to avoid driving or other activities that require alertness until response to the drug is known as this may cause drowsiness

Advise patient to change positions slowly to minimize orthostatic hypotension.

Caution patient that this medication may increase sensitivity to cold.

Instruct patient to consult health care professional before taking other Rx, OTC, or herbal products, especially cold preparations, concurrently with this medication. Patients on antihypertensive therapy should also avoid excessive amounts of caffeinated coffee, tea, and cola