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Did the symptoms change over time?

What is needed for someone to gain this disorder?
Rachael hyeon

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-Is this condition life threatening?
-How come his parents don't suffer from the same conditions even though his grandparents did?

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I wonder could this sickle cell disease kill Shawn?

I wonder how could he treat his condition?

I wonder why didn't Shawn's mother surfers from this symptoms but Shawn did?

I wonder if her mother knew it was a family history thing?

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-Why do Shawn’s red blood cells look like parts of it is missing or incomplete?

-Can these red blood cells be fixed?

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Has Shawn ever gone to the doctor to find out if he was diagnosed with asthma?

Does Shawn's family members have a disease that can be genetically given to the offspring?

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Were his red blood cells originally this thin shape while he was still in his early development stages as a fetus?
At what point in time did these symptoms start to show?

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1)Is Shawn’s illness was related to some kind of event that happened in his childhood?
2) If his parents did not have the illness that was supposed to be inherited, then how did Shawn get stuck with the illness?

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Did he have any less severe versions of the symptoms when he was younger?
Is he taking any medications the would give him these side affects?

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I wonder how Shawn compares to other patients that suffer through the same thing.
Is his condition fatal?

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I wonder if these red blood cells are bent into crescent shapes how are they supposed to carry any oxygen through the body at all and bring carbon dioxide out.

I wonder how this affects Shawn's body over time when his body organs are lacking its needed oxygen.

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Did the parents know about this genetic disorder?
Why didn’t Shawn’s parents suffer these symptoms but his grandmother and uncle did?

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I wonder if these red blood cells are bent into crescent shapes how are they supposed to carry any oxygen through the body at all and bring carbon dioxide out.

I wonder if his condition deadly.

I wonder how this affects Shawn's body over time when his body organs are lacking its needed oxygen.

I wonder if there is any treatment for his condition.

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Given that his HB is different than regular HB, can his HB be treated to be normal.

Can his sickle cells be treated and return to normal?

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-Is the pieces of blood red cells that Shawn has a genetic disorder?
-If Shawn were to have kids and get everything cured, would his kids also have these symptoms?
-How often do these symptoms occur?

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- Has Shawn always had these abnormally structured red blood cells or has it happened throughout time as he got older?
- Is there any possible solutions to restore his red blood cells?
- When did his symptoms start showing and how long have they been going on for?

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-How did Shawn get shriveled red blood cells and the Hb structure?
-Did the environment affect his blood cells or was he born with it?

-Is there a way to cure his red cells and his Hb?

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Did his parents know of this genetic disorder? If so, did they test Shawn to see if he inherited the disorder?
Why did these symptoms only start to show when he was 19?

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-Was he born with thin pieces of red blood cells or did the red blood cells thin as he got older?
-Are there any types of medications that would help cure his abnormalities?
-Since he lacks certain HB, would this  impact his symptoms?

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- Did these symptoms mutate over time? Were his parents the carrier in this case then?
- Did his HD change overtime? Why is the protein purple?

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Why do Shawn’s red blood cells look like parts of it is missing or incomplete?

Can these type of red blood cells be fixed?

What causes the sharp pain, is it the shape of the red blood cells or something else?

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-How does the hemoglobin in Shawn’s blood work differently from a normal person’s hemoglobin?
-What caused Shawn’s red blood cells to be shaped like that?
-How do red bloods cells shaped like that function in Shawn’s body?
-Since when did these symptoms start showing?
-Did the family members who also showed these symptoms pass them down?
-How often would these symptoms show?

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When did his blood cells start to become that thin- ever since he was born or as he got older?

Did the symptoms worsen with age?

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Does Shawn have other health related issues?

How long does the symptoms usually last?

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Can a sickle cell reverse back to a normal cell?

What made Shawn have sickle cell disease?

Is sickle cell disease curable?

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-If shawn has kids would his kids also have this symptom?
-when did these symptoms start?

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Were his blood cells already very thin right when he was a fetus?

If this condition is inheritable, what makes Shawn symptomatic while some of his siblings aren’t?

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- What could have triggered his red blood cells to change like that recently?
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Do they have to have the same DNA to get this disorder?

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Is there a way to restore his blood cells, and will that cure his symptoms?

Do his family members have the same blood cells as well, or are they different from Shawn's?

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Was Shawn born with shriveled blood cells or did that change as he got older?

Could he have taken any medications to change his red blood cell shape or was that in his DNA?

Why does Shawn’s Hemoglobin contain pinkish-purple parts, while the normal one contains red spots?

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- Did Shawn and his family members with this disease get any treatments?
- When did these symptom start showing up?

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Directions:  Go to the plus sign in the lower right corner to add your questions to our Wonder Wall.

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Directions:  Go to the plus sign in the lower right corner to add your questions to our Wonder Wall.

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Wonder:  Scientific questions lead to explanations of how the natural world works and can be tested using evidence.  Scientists ask questions to develop or refine an explanation about the natural world.  What scientific questions do you have about what you have observed so far?