# data[].attributes.body
Individual

Question- Does ginger reduce nausea during pregnancy?

# data[].attributes.body
Population - Pregnant women

Intervention - Ginger

Comparison - No comparison

Outcome - Reduced nausea

# data[].attributes.body
Decided to research databases such as Pubmed, TRIP and Cochrane.

We searched using Boolean operators 'AND', such as, 'Pregnancy AND ginger AND nausea' to expand the search. This enabled us to find papers that used all these terms, giving us a wide variety of results.

Pregnan*

Nause*

# data[].attributes.body
Cochrane didn't show any relevant results as there were no systematic trials relevant to this study.

# data[].attributes.attachment_link.title
A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting[9]

# data[].attributes.body
Searched PUBMED

Filtered to RCT and Systematic Reviews

48 results in total

19 irrelevant

8 included specific groups e.g. cancer patients undergoing chemotherapy, post-op and pre-op patients, as well as many other treatments to ginger which meant the search was too wide.

19 excluded as they were not within the last 10 years

3 were sufficient and narrowed it down 2 because the sample size was greater in the RCT

# data[].attributes.body
Only included RCT involving human participants.

Had a wide variety of ginger products used in trial including ginger biscuits, powder capsules, ginger syrup in water, ginger essence capsules, ginger extract capsules and ginger capsules.

Used Cochrane risk of bias tool when analysing RCTs

Papers were critically analysed by two independent researchers

Included what data bases were searched including boolean operators and wildcards.

Used the five point Likert type scale to measure results

Clarified confidence intervals.

# data[].attributes.headline
Limitation of Randomised Controlled Trial

# data[].attributes.subject
Limitation of Randomised Controlled Trial

# data[].attributes.body
Does not clarify care criteria for research participants

Study limited to people 6-16 weeks pregnant

Does not have a clear conclusion

Not clear how many women started trial. (77 women finished)

Cannot track women who participated in trial

Uses standard deviation instead of confidence interval.

Does not address adverse affects

# data[].attributes.body
No limit in women's age or stage of pregnancy.

Only included English language studies.

Majority of RCTs included in review scored for a high risk of bias on Cochrane Risk of Bias tool.

No blinding used.

Only four RCTs used V6 as a comparison, and other trials didn't have a placebo- hard to generalise papers.

# data[].attributes.headline
Strengths of Randomised Controlled Trial 

# data[].attributes.subject
Strengths of Randomised Controlled Trial 

# data[].attributes.body
Triple blind clinical trial

Used a visual analogue scale.

Rhodes score scale used

Focused on research question

Groups were randomly allocated, block random sampling

# data[].attributes.attachment_link.title
A comparison between the effects of ginger  pyridoxine  vitamin B6  and placebo for the treatment of the first trimester nausea and vomiting of pregna