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Concern if there will be a negative impact on behavior in areas of less social play, courtship, parenting. Staying in heat longer, documented case of 6 months instead of 1 month.

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Labor intensive to hunt and dart deer with vaccine. Cheaper to manage the deer population by bullets however this is frowned on by public opinion. Focus area is in suburban areas where deer demographics range 20,000-50,000 across the U.S. Deer Range from a few dozen to few hundred per site.

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PZP-  Derived from animal tissue for the female immune system to block sperm from females eggs.Administerd twice in the first three months, then annually.
GonaCon- gonadotrophin-releasing hormone (GnRH), preventsestrus, ovulation. and mating. It is grown in recombinant bacteria. Currently up to 5 years 4 out 5 are infertile

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Hormonal implants, immune vaccines,cholesterol drugs, viruses, and worms engineered to stop reproduction.

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Surburban areas are fragmenting the landscape.
Accidents happen while female white-tail deer (Odocoileus virginianus) are being pursued by (male) stag, such as running into traffic. 1.5 million traffic accidents are caused by deer collisions. Insurance claims are 3 x higher in November.

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Fundamental goal is to downsize natural ecology to fit the geography of modern niches without altering the behavior of animals or the balance between species.

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Modified live vaccine (MLV)
Inactivated rabies vaccine
Oral MLV
Recombinant rabies virus-vectored vaccines
Recombinant poxvirus-vectored vaccines
Recombinant adenovirus-vectored vaccines
DNA-based rabies vaccines
Oral rabies vaccines derived from plants

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Video

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Wildlife Services' Oral Rabies Vaccine Bait Program

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Wildlife Services Deputy Administrator Bill Clay and Jordona Kirby, field coordinator for the National Rabies Management Program, explain the oral rabies vaccine bait program administered by wildlife biologists and technicians from the Animal and Plant Health Inspection Service (APHIS) Wildlife Services program.

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RABORAL V-RG is an oral rabies recombinant vaccine that protects raccoons and coyotes against rabies.
The recombinant vaccine is encased inside a plastic packet. The packets, also called sachets, are encased inside solid fishmeal baits or the sachets are simply covered in a fishmeal-based coating.These baits are distributed to disignated areas.

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1.https://www.popsci.com/science/article/2011-08/birth-control-wildlife

2.http://www.conservationmagazine.org/2008/07/wildlife-contraception/
3.https://www.aphis.usda.gov/wildlife_damage/nwrc/symposia/contraception_symposium/guynn.pdf
4..https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693202/
5.https://www.ncbi.nlm.nih.gov/pubmed/19656957
6. http://www.deerfriendly.com/deer-population-control/deer-birth-control-contraception

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1.http://epi.publichealth.nc.gov/cd/rabies/orv.html
2. http://www.raboral.com/

3.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623496/

4.http://www.who.int/rabies/vaccines/recombinant/en/
5. Feldhamer, G. A. (2007). Mammalogy: adaptation, diversity, and ecology (3rd ed.). Baltimore, MD: Johns Hopkins University Press.

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To humans mostly by bite wounds, cuts, or less common mucous membranes or from inhalation

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Carnivores are the primary reservoir for the maintenance and transmission of rabies world wide.
Domestic dogs are main main carrier in developing countries. In developed countries wildlife and companion pet exposure to wildlife are at higher risk.
In North America hosts are raccoons (Procyon lotor), striped skunk (Mephitis mephitis), usually red fox (Vulpes vulpes), and various species of bats.
Rodents and lagomorphs can transmit, but are not considered reservoirs

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30-90 days after exposure fever and headaches will occur. After inoculation, the virus infects nerve tissue, spinal cord and then to the brain. It multiplies quickly in the brain and moves along peripheral nerves throughout the body.
Feelings of apprehension, agitation, disorientation, followed by hypersalivation and paralysis. Once symptoms start, death occurs within a week or sooner.

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Molecular strains of RNA Viruses. Genus Lyssavirus, in Greek lyssa means "madness". It occurs in a variety of mammal hosts.