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The equilibrium potential is the diffusion potential that exactly balance the tendency for diffusion caused by a concentration difference. At electrochemical equilibrium, the chemical and electrical driving forces that act on an ion are equal and opposite and no more net diffusion of the ion occurs

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The equilibrium potential is the diffusion potential that exactly balance the tendency for diffusion caused by a concentration difference. At electrochemical equilibrium, the chemical and electrical driving forces that act on an ion are equal and opposite and no more net diffusion of the ion occurs

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The sing of the DP depends on whether the diffusing ion is positively or negatively charged

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The sing of the DP depends on whether the diffusing ion is positively or negatively charged

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is expressed as the measured potential difference across the cell membrane in millivolts (mV)

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is expressed as the measured potential difference across the cell membrane in millivolts (mV)

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¿A DÓNDE SE CONECTA ESTE CONCEPTO?

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A DP can be generated only if the membrane is permeable to the ion

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A DP can be generated only if the membrane is permeable to the ion

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~ -70mV is expressed as the measured potential difference across the cell membrane in millivolts (mV)

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~ -70mV is expressed as the measured potential difference across the cell membrane in millivolts (mV)

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The conductance of a channel depends on the probability that the channel is open. Higher probability --> higher conductance or permeability	

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The conductance of a channel depends on the probability that the channel is open. Higher probability --> higher conductance or permeability	

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opening and closing of channels are controlled by gates

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opening and closing of channels are controlled by gates

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The size of the DP depends on the size of the concentration gradient

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The size of the DP depends on the size of the concentration gradient

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The Nerns equation is used to calculate the equilibrium potential at a given concentration difference of a permeable ion across the cell membrane. It tell us at what potential would the ion be at electrochemical equilibrium

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The Nerns equation is used to calculate the equilibrium potential at a given concentration difference of a permeable ion across the cell membrane. It tell us at what potential would the ion be at electrochemical equilibrium

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Each permeable ion attempts to drive the membrane potential toward its equilibrium potential. Ions with highest permeabilities, or conductances, will make the greatest contribution to the resting membrane potential, and those with the lowest permeabilities will make little or no contribution

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Each permeable ion attempts to drive the membrane potential toward its equilibrium potential. Ions with highest permeabilities, or conductances, will make the greatest contribution to the resting membrane potential, and those with the lowest permeabilities will make little or no contribution

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 The activation gate of the Na channel in nerve is opened by depolarization; when open, the membrane is permeable to Na

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 The activation gate of the Na channel in nerve is opened by depolarization; when open, the membrane is permeable to Na

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The resting membrane potential is established by diffusion potentials

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The resting membrane potential is established by diffusion potentials

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Ion channels are selective; they permit the passage of some ions but not others (depending: size and charge)

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Ion channels are selective; they permit the passage of some ions but not others (depending: size and charge)

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 Voltage-gated channels are opened or closed by changes in membrane potential	

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 Voltage-gated channels are opened or closed by changes in membrane potential	

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 A diffusion potential (DP) is the potential difference generated across the membrane because of a concentration difference of an ion	

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 A diffusion potential (DP) is the potential difference generated across the membrane because of a concentration difference of an ion	

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BIOELECTRICAL PHENOMENA

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 Ligand-gated channels are opened or closed by hormones second messengers or neurotransmitters

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 Ligand-gated channels are opened or closed by hormones second messengers or neurotransmitters