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Sickle cell anemia is a common hereditary disease, which produces deformed, hardened red blood cells that carry less oxygen and can not move in circulatory system easily .

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sickle cell anemia

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-Episodes of pain called crisis.
-Delayed growth.
-Yellowish of skin and eyes because of liver damage.
-Strokes
- Heart problems

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Sickle cell anemia is caused by a mutation in a blood protein called beta globin. which cause change in the shape and behavior of red blood cells (sickle shape).

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This diseases is passed by gene from parents to their children. Both copies of gene in each cell have mutation.where child will get each copy of mutated gene.

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Autosomal recessive inheritance

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-Test to detect sickle cell gene before birth
-Blood test to check for anemia

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-A bone marrow transplant
-Blood transfussions

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-In African Americans affect 1 in every 375 children
-Globally, a quarter of a million children are born with this disease.