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IgM (always 1st)

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Active B cells (plasma cells): produce antibodies

Memory B cells (remember)

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Th2 for:  bacterial, fungal, parasitic worm, allergens, protozoans

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Th2 for:  bacterial, fungal, parasitic worm, allergens, protozoans

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Kill abnormal self cells (virally-infected, cancerous, transplant)

Active cytotoxic T cells & MEMORY T cells (remember antigen)

Use CD8 & TCR to check for abnormal self antigens displayed on MHC1

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Viral infection use Th1 general

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CD4+ T helper cells use TCR to recognize antigen

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MHC2 display antigen to Th1

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Macrophages present antigen to Th2 general using MCH

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Macrophages present antigen to Th2 general using MCH

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Release perforins (punch holes in cell)
Release granzymes (digest cell)