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An ambulance takes Abigail to the hospital. Callahan is arrested. Hiro and his friends are back at nerd school. Hiro creates a new Baymax. Inside is the Tadashi chip. They hug. At the very end, we smell sequel city. Hiro says to his friends, “My brother wanted to help a lot of people and that’s what we’re going to do. What are we? Big Hero Six!”

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Krei is making a speech and the nerds arrive. Callahan shows up with the bots and confronts Krei, “You took everything from me, now I’m taking everything from you.” Hiro says, “Is this what Abigail would want?” But Callahan won’t back down. There’s a huge fight. Baymax is injured, Hiro almost gets sucked up into the dangerous portal that Callahan has created. His friends are trapped. Hiro figures out a way to break apart the bots so they get sucked up into the portal. But Baymax detects signs of life in the portal. It’s Abigail. She’s in hypersleep, still alive. Hiro and Baymax go into the portal to save her. They rescue Abigail, but the only way to get Hiro and Abigail back to earth is for Baymax to sacrifice himself and stay behind. Baymax asks, “Are you satisfied with your care?” Hiro says he can’t lose him too. Baymax replies, “I will always be with you.” They hug.  Baymax pulls the thruster which pushes Hiro and Abigail back through the portal.

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Hiro’s friends show up. Hiro apologizes. He says that they’ll catch Callahan and do it right.

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Hiro is so angry that he throws out Tadashi’s smiley face chip. Baymax can now kill. Baymax chases Callahan and attacks everyone. The nerds put Tadashi’s smiley face chip back into Baymax to stop him. Hiro’s friends say they don’t want to destroy Callahan, they just want to catch him. Hiro wants him dead. He takes Baymax off by himself. He starts to permanently take out Tadashi’s chip, but accidentally activates a video that shows his brother’s efforts to create a healer not a killer.

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Baymatch’s super sensor finds Krei on an island. The six friends break into the compound and discover, via video footage, that Krei shot an astronaut named Abigail into space, and she died. Krei shows up in his mask. The nerds attack him. One by one, Krei disables them. Baymax attacks him and the mask comes off.  It’s professor Callaghan! He didn’t die in the explosion. He built the bots and is responsible for Tadashi’s death.

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After a nerve racking chase through the city, Baymax leads Hiro to a warehouse. They climb inside and Hiro discovers tiny bots, just like his own, being manufactured. Someone’s making more.Suddenly, the bots rise up and become threatening. As Hiro and Baymax are chased, they see an evil dude with a Kabuki mask who is controlling the bots.

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While in his room, Hiro accidentally inflates Baymax. Under his brother’s bed, Hiro also finds one of his own tiny bots that wasn’t destroyed in the explosion. It seems to want to find other bots. But weren’t they destroyed too? Baymax rushes out of the house to find the other bots. Hiro races after him.

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But then theres a huge explosion and when Tadashi runs back into the lab to his teacher Callahan, he is killed. Hiro is distraught and depressed about his brothers death. His aunt (which they lived/live with) encourages him to go and his brother friends they miss him, but Hiro throws away the registration materials.

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Hiro enters the lab and is dazzled by all the cool invention his brother and his brothers friends made. Hiro's brother Tadashi shows him his own invention, a healthcare robot named Baymax.