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Sexual contact (STD)

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1. Antibiotics (penicillin, tetracyclins, spectinomycin)

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Discovered by a German physician named Albert Neisser.

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gram negative, aerobic, non motile , mesophilic (35-37 temperature).
Cause gonorrhoea- sexually transmitted disease (STD)

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Diplococci

0.6 - 1.0 micrometer in diameter

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women

odorless vaginal discharge

vaginal bleeding, particularly after intercourse

dyspareunia

cervicitis with mucopurulent drainage from the os

infertility

acute salpingitis with or without endometritis, also known as PID

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women will have higher risk to get infection.
Characterized by purulent discharge for involved site after 2-5 days incubation period.
how it infect
1. opa protein and pilus of gonococci can help in binding to mucosal epithelium.
2. opa protein will attach to the CD66antigen of the mucosal cells.
3. bacterial will enter into the mucosa cells
4.gonococci can transport across to the mucosal epithelium (transcytose)
5. with the help of opa protein, the gonococci halp reside and survive inside the neutrophils
6. under the process of transctose, gonococci can enter blood stream, and with the aid of the LOS, it helps the bacteria resistant to the serum

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men

purulent penile discharge

dysuria

fever

epididymitis

unilateral testicular pain without discharge or dysuria

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Pelvic inflammatory disease

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usage of condoms