# data[].attributes.body
Jessica Nguyen

Mr. Heriveaux

Biology 1 - 005

7 April, 2019

Genetic Disease Text

1. Other Names for Hemophilia A are Classic Hemophilia, since it is more common, and Factor VIII deficiency hemophilia, since it lacks the factor VIII protein.

2. The cause of Hemophilia A is a mutation in the gene for Factor VIII.

3. The X chromosome is affected by Hemophilia A.

4. The symptoms of Hemophilia A are pain in the joints, bruising, nose bleeds, internal bleeding, unusual bleeding, excessive bleeding, and blood in urine.

5. Hemophilia A is inherited by a  recessive X linked pattern.

6. If a woman is a carrier of the hemophilia gene, there is a 50% chance that a son will have hemophilia and 50% chance that a daughter will have hemophilia.

7. Prenatal test for hemophilia A relies on chorionic villus sampling.

8. In the US, 1 in 5,000 males are affected with Hemophilia A during birth. Typicalling Hemophilia affects males since it is X linked,

9. An affected child will need physical therapy and exercise to strengthen the muscles around the area. If major blood loss has occurred, blood transfusions may be needed. Bleeding in the head can cause long term problems such as paralysis and seizures. If the bleeding cannot be stopped, death may occur.

10. Medical Treatment for Hemophilia is called Factor Replacement Therapy. This is when concentrations of clotting factor VIII are injected into the vein.

11. Since Hemophilia is a genetic disease, hemophilia cannot be prevented.

12. Currently, researchers are trying to discover a new method to better insert a functioning factor VII gene into cells of people with hemophilia so that the blood would clot more effectively. Currently there is still no cure for Hemophilia.

“Future Therapies.” National Hemophilia Foundation, 27 Feb. 2017, www.hemophilia.org/Bleeding-Disorders/Future-Therapies.

“Hemophilia - Genetics Home Reference - NIH.” U.S. National Library of Medicine, National Institutes of Health, ghr.nlm.nih.gov/condition/hemophilia.

“Hemophilia A.” Hemophilia Federation of America, www.hemophiliafed.org/understanding-bleeding-disorders/what-is-hemophilia/hemophilia-a/.

“Hemophilia in Children.” Johns Hopkins Medicine Health Library, www.hopkinsmedicine.org/health/conditions-and-diseases/hemophilia-in-children.

“Hemophilia.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 20 Dec. 2018, www.mayoclinic.org/diseases-conditions/hemophilia/symptoms-causes/syc-20373327.

“Hemophilia.” National Heart Lung and Blood Institute, U.S. Department of Health and Human Services, www.nhlbi.nih.gov/health-topics/hemophilia.

“How Do You Get Hemophilia?” How Do You Get Hemophilia? - World Federation of Hemophilia, www.wfh.org/en/page.aspx?pid=644.

Stöppler, Melissa Conrad. “What Is Hemophilia? Definition, Symptoms of Hemophilia A and B.” MedicineNet, www.medicinenet.com/hemophilia/article.htm.

Stöppler, Melissa Conrad. “What Is Hemophilia? Definition, Symptoms of Hemophilia A and B.” MedicineNet, www.medicinenet.com/hemophilia/article.htm.

Tsui, Nancy B. Y., et al. “Noninvasive Prenatal Diagnosis of Hemophilia by Microfluidics Digital PCR Analysis of Maternal Plasma DNA.” Blood Journal, American Society of Hematology, 31 Mar. 2011, www.bloodjournal.org/content/117/13/3684.

“What Is Hemophilia | CDC.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, www.cdc.gov/ncbddd/hemophilia/facts.html.

“What Is Hemophilia?” Hemophilia, www.hemophilia.ca/what-is-hemophilia/.

# data[].attributes.body
The X chromosome is affected by Hemophilia A.

# data[].attributes.headline
How can knowledge about macro-molecules we put in our body affect our health and nutrition. 

# data[].attributes.subject
How can knowledge about macro-molecules we put in our body affect our health and nutrition. 

# data[].attributes.body
Most of them are based on calorie restriction or minimizing intake of one of the major macro-molecules found in food – fats, carbohydrates, and proteins. Probably the most famous example of this is the Atkins diet, which suggests you cut carbohydrates out of your diet and sustain yourself on protein and fat. If you know exactly what you put in your body, unhealthy and healthy, it could save your heath and prevent health issues in the future.
By: Patrick Brown, 3rd year PhD candidate in the Biomedical Sciences Program

# data[].attributes.body
Many believe lipids do not consist of true monomers because the subunits of lipids, glycerol and fatty acids, attach to each other, rather than attaching to other monomers that are similar in molecular structure.

Below is an image of a triglyceride molecule, which contains of three glycerol molecules chained onto fatty acids, which are long carbon chains bonded to hydrogen.

# data[].attributes.body
1. Store energy long term
2. Protects against heat loss
3.Serve as a source of fat and vitamins

# data[].attributes.body
Many foods that contain a lot of what makes up lipids; fatty acids have saturated fats. Examples are dairy products; milk, cheese, butter  and meats; beef, pork, lamb, and processed. It's important to know what types of foods contain high amounts of lipids because if you're constantly consuming these products you can develop health risks.

# data[].attributes.headline
What happens when you eat too much/too little lipids

# data[].attributes.subject
What happens when you eat too much/too little lipids

# data[].attributes.body
Eating too many lipids can raise cholesterol levels in the blood. It will also increase the risk of heart disease. Although eating too many lipids can cause some harm, you shouldn't dismiss then completely from your diet because lipids allow you to absorb plenty of nutrients.

# data[].attributes.body
All lipids contain carbon, hydrogen, and oxygen. Some of them also contain nitrogen and phosphorus.