# data[].attributes.body
Basically its depend on which organelle is not functioning well.
If its individual mitochondrion, well its no problem. Since the cell has dozens of others. If its the nucleus. Then the cell's going to be malfunctioning, since there is only one nucleus and it is really important.

# data[].attributes.body
Nucleus
-For multicellular life forms which called eukaryotes, nucleus is needed for it to exist. Nucleus acts as the administrator center storing its genetic material and coordinating its activities. If the nucleus stops working, the cell will stop working, the cell would start dying and if the nucleus stops working for many cells, there will be died cells in your
body doing nothing. After the nucleus shuts down, all of the organelles stop working. Usually when the cells dies, the centrioles divide the cell but when the nucleus dies everything shuts down at once
so the centrioles don't have time to make the effect.

# data[].attributes.body
Molecular Expressions explains that simple, one-celled organisms, or prokaryotes, such as bacteria, do not have a nucleus. Instead, their genetic material is dispersed throughout the cell. Eukaryotes, on the other hand, require a greater degree of cellular organization because they perform more complicated functions. These functions include cell reproduction, growth, protein synthesis and intermediary metabolism. A membrane separates the nucleus' contents, which include strings of genetic material called DNA, from the rest of the cell. Each nucleus within a human cell contains nearly 6 feet of DNA arranged into a compact structure known as chromatin. This chromatin organizes to form chromosomes during cell division.

Each nucleus also contains at least one nucleoli, an organelle responsible for synthesizing ribosomes, which produce proteins along with other small cell components. The membrane of the nucleus is full of small holes that allow necessary molecules to pass between the nucleus and the rest of the cell, such as building blocks for DNA and RNA and energy-supplying components, notes Molecular Expressions.

# data[].attributes.body
If the nucleus failed to work, then immediately the cell would cease to function because no direction or synthesis would be available. The ERs handle, at least in simple terms, protein production necessary for cell life. If the Golgi stopped, all of the cells produced material would buuld up in the cell and nothing could be transported from the cell, ending in collapse. Lysosomes protect and destroy foreign or unwanted substances, so those ceasing would probably end in the cell dying of an infection or foreign problem. The vacuoles are not organelles but are simply small bubbles of membrane used for transport, they bring in necessary substances from the outside of the cell using glycoproteins. Chloroplasts are in only plant cells, and give the cell energy- without them, no energy to do things. Same goes for mitochondrion, except they can be in both animals and plants. Cytoskeleton is necessary only in animal cells and without it the cell would collapse and cease to function. The cilia/flagella regulate movement, and altho arent necessary to the cell directly, and altho they arent always on cells, could have a negative effect if the cell could not get to its needed location.

# data[].attributes.body
Cells are mainly classified in two types, the eukaryotic cell and the prokaryotic cell. Both has their own significance and differences. But, if an organelle fails to function in both types of cells, it will affect many processes of the cell. For example, the peroxisomes in eukaryotic cells Peroxisomes function as a major site for oxygen utilization in the cell in which the peroxisomes regulate the concentration of oxygen in a cell. If the oxygen is not utilized, oxygen produced by photosynthetic bacteria will accumulate in the atmosphere and would have been highly toxic to most cells (Alberts et al., 2002).In humans, specifically in the liver, function of the peroxisome is to break down excess fatty acids to constituent carbon atoms by beta oxidation. Failure for the organelle to do so will result in fatty liver, which is the accumulation of fatty acids in the liver cell. Fatty liver may lead to decreased the rate of fatty acid beta oxidation and enhances the delivery of fatty acid to the liver causing more fatty acid to be accumulated which can cause diseases such as liver failure. Peroxisomes are also important in plants as they assist in the process of photosynthesis. Specifically, it helps the chloroplasts in plant cells during photorespiration. Peroxisomes mainly participates in photosynthetic reactions as the concentration of atmospheric O2 increases. This is because peroxisomes is responsible to regulate the flow of O2 and CO2 in plant cells. If the flow of both gases is not balanced, it will cause a decline in plant productivity.

# data[].attributes.body
A cell without a functioning organelles will fail to work. And the cell cannot work the organism will die. If cells did not have any mitochondria, they would have to use anaerobic glycolysis to produce ATP, This process converts glucose into a substance called pyruvate, but it is less efficient than aerobic respiration so only a small amount of the energy from glucose is released. Humans also need mitochondria to produce cholesterol and a component of hemoglobin, it is likely humans would still not be able to survive without mitochondria to help regulate these functions.

Another example, if lysosome in cell does not work properly would cause accumulation of the pathogens and unwanted particles which leads to lysis of the cell.

# data[].attributes.body
Mitochondria, nucleus, golgi apparatus, lysosome, endoplasmic reticulum, ribosome and chloroplast are the examples of the organelles. Each of the organelles perform a specific functions within the cell. The larger organelles within the cell is nucleus which contains the genetic materials called  chromosomes that made up of DNA. For instance, if the nucleus does not function, the genetic makeup located within the cells will damage and will causes the cell to not functioning well in the cell divison and become neoplasm. The nucleus itself contains many different parts such as nucleotide, nucleoproteins and cell nucleolus where the DNA and RNA was stored. If the DNA damaged it will lead to suppression of RNA synthesis and will cause the cell to initiate nucleotide excision repair. In addition, if the nucleus was not functioning well it also will damage other oragnelles such as cell membrane or mitochondria an will cause the numerous death cell. So, if one organelle damage it can damage the whole cell.

# data[].attributes.body
An organelle is a tiny cellular structure that perform specific functions within a cell. The malfunction of one of the organelles in the cell will give rise to various outcomes.

For instance, the nucleus functions as the control centre of the cell, meaning, the nucleus controls all of cell activities, including the process of cell division. If the nucleus failed to work properly, the regulation of cell division will be interrupted, resulting in an uncontrollable division of the cell.

Another example is, if the function of rough endoplasmic reticulum is at default, the cell will not be able to synthesise protein as the main function of the organelle is carrying out translation and folding of new proteins. Protein is essential for reactions like metabolism, DNA replication and transportation of molecules. If the cell lacks protein, then cell growth, reproduction, and healing would be impossible. If the smooth endoplasmic reticulum does not function properly, there will be no production of lipid based steroid hormones and the detoxification of substances will be impossible.

In addition, the mitochondria is responsible for generating more than 90% of energy needed by the body to sustain life and support growth. It is in the form of energy-rich molecule ATP that is readily usable by the cell. The ATP is used by the cell to carry out energy-requiring processes like biosynthesis, transport of molecules or ions against the concentration gradient, and generation of mechanical force for instance, for muscle contraction. Thus, the malfunction of this organelle will impede all these processes and disrupt the activities of the cell. When mitochondria fail, the production of energy within the cell declines, resulting cell injury and subsequently the death of the cell and the whole system will start to fail if this process is repeated throughout the body.

The Golgi apparatus is an organelle in the cell that functions to modify, sort and package proteins in a new vesicle to be transported to specific destinations inside and outside of the cell. If the organelle does not function well, the proteins will not be packaged which will cause the absence of digestive enzyme in lysozyme, and hence resulting in the build-up of materials.

In plants, the malfunction of an organelle called the chloroplast will impede photosynthesis. No photosynthesis means no energy in plants and the plants will die.

# data[].attributes.body
Most of the organelles important for the cells to functioning well. The nucleus fail to function the all cell will stop functioning because there is no direction or synthesis would be available. If the chloroplasts in plants stop functioning it can cause dead to the plants because there is no energy provided to the plants. Each of the organelles playing important roles to the well function of the cells

# data[].attributes.body
Fundamental processes would not be able to be carried out. Our entire body depends on many of this complex processes. If one does not occur, it can and may cause harm to our body. For example, if the endoplasmic reticulum is not working, how is protein going to be synthesised? And if there is no protein, how are hormones going to be produced? It is pretty much a cycle, if something is not working well or is absent, the whole cycle in our body is disrupted.

# data[].attributes.body
Organelles in the cell is depending to one another. For example, conversion of food energy to ATP happen in mitochondria. Energy comes from the protein, carbohydrates and fat. But we cannot use these sources of energy directly until it be convert into ATP. If mitochondria cannot functioning well, then the food that we consume will be less likely be converted into ATP. The process of producing ATP also will produce heat to our body to make our body to stay in its essential temperature. Also for the tissues that require a lot of ATP which is muscle tissue, if the mitochondria in this region does not functioning well, they may become weaker and tired faster and lead into muscles cramp.

# data[].attributes.body
The cytoskeleton is functioning for cell shape, motility (movement) of the cell and motility of organelles within a cell. Therefore, when the cytoskeleton is not functioning, the disease that may occur is Alzheimer's Disease (AD) development

# data[].attributes.body
Each organelle in a cell have their specific functions. All this functions are somehow related with one another. For instance, the sequence of events from protein synthesis on the rough ER to the final distribution of these protein. Protein-containing vesicles pinch off rough ER and migrate to fuse with membranes of golgi apparatus. Next, proteins are modified within the golgi compartments. Then, proteins are then packaged within different vesicle types, depending on their ultimate destination. Imagine if golgi apparatus is absent in the cell, this process will probably become incomplete and meet failure. Protein synthesis is very important as the protein produce control the activities of the cells and without it many processes in the body would fail or not working properly.

# data[].attributes.body
When one of the organelles in the cell does not function well, it will effect the activity and function of the cell. For example, if the lysosome in the cell does not function, it will cause the accumulation of the pathogens and other unwanted particles which can cause the death of the cell because lysosome's function is to degrade harmful foreign particles

# data[].attributes.body
Every organelle plays important roles in the cells. If the nucleus is not functioning well, the dna replication and translation will facing a big problem since nucleus is the major organelles for these process to be happened. Nucleus contain the genetic information which is essential for the inheritance of the species. If it does not function well, the next genetic of an organism might be facing mutation.

# data[].attributes.body
Each organelles plays an important role in secretory and endocytotic in cell . If one of the organelles is dysfunctional it can leads the cell to die. Plus , the cell cannot produce  protein as if one organelle is not functioning . For Examples , Golgi complex plays role in modification and transportation of protein from Rough Endoplasmic Reticulum to release to the target cell . If Golgi Complex is not work well in cell , the synthesis protein that had been produced by RER cannot be modify and transport to the target cell .

# data[].attributes.body
Organelles play an important role in secretory and endocytotic pathways for examples of endoplamic reticulum , Golgi Complex,Lysosomes and Endosomes. If there were malfunction of these organelles , it will lead to dysfunctional of cell and can cause the cell to die .

# data[].attributes.body
Certain dysfunctional of organelle will lead to a specific malfunction of cell. Taking the cell membrane as an example, without the cell membrane, the call may die as cell membrane provides several vital functions for the cell. Cell absorbs nutrient from the cell membrane and expel waste through the same medium. The cell membrane also embeds specific proteins which is used to communicate. These interactions are considered vital for the functionality of a certain organism.

# data[].attributes.body
Lysosomes are the one of the organelle in the cell. Lysosomes are the membrane-bound vesicles, which contain digestive (hydrolytic) enzymes like acid hydrolase. They digest a variety of substances including worn out organelles, food particles, viruses, and bacteria.
If there were no lysosomes in the cell, it will not be able to digest food and there would be accumulation of wastes like worn out parts inside the cell. Thus, cell will not be able to survive.

# data[].attributes.body
Ribosomes are one of the organelle in the cell. Ribosomes are the cellular component that synthesis proteins. Ribosomes are made from complexes of RNAs and proteins. Ribosomes are freely suspended in the cytoplasm or attached to the endoplasmic reticulum forming the rough endoplasmic reticulum. But the malfunction of ribosomes will cause a disease ribosomopathies. It is a disease that compose a collection of disorders in which genetic abnormalities cause impaired ribosome biogenesis and function, resulting in specific phenotypes. Abnormal ribosome biogenesis is linked to several human genetic diseases, which are characterized by a predisposition to cancer and a reduced number of blood cells. Such as t Diamond Blackfan anemia (DBA), Dyskeratosis congenita (DKCX) and Treacher Collins syndrome (TCS). To summarize, every single of organelle in cell plays crucial roles. The malfunction of organelles may cause fatal to cell and also to an organism.

# data[].attributes.body
Living cells use proteins for structural units, as transportation mechanisms between the interior and exterior and as specialized chemical catalysts called enzymes. Without ribosomes, no proteins would exist to perform those tasks, or any of the many other jobs that proteins do. If nucleus is damaged, the genetic makeup located within the nucleus could also suffer damage on its own. In this case, it often causes the cell to lose normal control of the function that regulates cell division, causing the cell to continue to divide and become a neoplasm. In addition to damage to the nucleus, damage to the other structures of the cell, such as the cell membrane or mitochondria, can cause numerous problems and potentially lead to the death of the cell. If the Golgi apparatus was damaged, protein shape, hence function may be altered. Besides, chloroplasts are in only plant cells, it gives the cell energy. Without them, there is no energy to do things. Cytoskeleton is necessary only in animal cells and without it the cell would collapse and cease to function. Also, lysosomes protect and destroy foreign or unwanted substances, so those ceasing would probably end in the cell dying of an infection or foreign problem. The vacuoles are not organelles but are simply small bubbles of membrane used for transport, they bring in necessary substances from the outside of the cell using glycoproteins. Also, if mitochondria does not work, there is no energy provided to the cell. Hence, the cell get weak and lost to function. The cells and organelles all need each other. In many reaction in the cell, many different organelle's are needed. If one doesn't work, the cell will die and if this happens on a large scale then this could be fatal for the organism.

# data[].attributes.body
If the nucleus is not function well, the cell would fail to function because no direction or synthesis would be available. The ERs handle, at least in simple terms, protein production necessary for cell life. If the Golgi stopped, all of the cells produced material would build up in the cell and nothing could be transported from the cell, ending in collapse. Lysosomes protect and destroy foreign or unwanted substances, so those ceasing would probably end in the cell dying of an infection or foreign problem. Chloroplasts are in only plant cells, and give the cell energy. Thus, without them, no energy to do things. Same goes for mitochondrion, except they can be in both animals and plants.

# data[].attributes.body
Cell is the building blocks of life because they are the basic unit for all living organisms. They play a crucial role in maintaining the organisms’ life. Cells contain components which help to regulate the processes in our body. If one of the organelles in the cell does not function well, the cell will not be able to function at all or effectively since each organelle in the cell contributes in their own way to make the cell functions as a whole. For example, the nucleus is the biggest organelle in the cell. It stores the DNA and control the cell activities. If the nucleus is damaged, the DNA could not be stored. Then, if mitochondria does not function well, less energy will be provided to the cell hence slowing down the activity of the cell making an organism fatigue. Mitochondrial dysfunction can cause mitochondrial disease and it affects organs in the body that require the most energy such as the brain, muscles, liver, kidney, and heart.

# data[].attributes.body
Without a nucleus, multicellular life forms, called eukaryotes, would not exist.According to the Molecular Expressions website from Florida State University, the nucleus acts as the administrative center and information processor for the cell by storing its genetic material and coordinating its activities. Molecular Expressions explains that simple, one-celled organisms, or prokaryotes, such as bacteria, do not have a nucleus. Instead, their genetic material is dispersed throughout the cell. Eukaryotes, on the other hand, require a greater degree of cellular organization because they perform more complicated functions. These functions include cell reproduction, growth, protein synthesis and intermediary metabolism. A membrane separates the nucleus' contents, which include strings of genetic material called DNA, from the rest of the cell. Each nucleus within a human cell contains nearly 6 feet of DNA arranged into a compact structure known as chromatin. This chromatin organizes to form chromosomes during cell division.

Each nucleus also contains at least one nucleoli, an organelle responsible for synthesizing ribosomes, which produce proteins along with other small cell components. The membrane of the nucleus is full of small holes that allow necessary molecules to pass between the nucleus and the rest of the cell, such as building blocks for DNA and RNA and energy-supplying components, notes Molecular Expressions

# data[].attributes.body
Basically, each organelle has its own characteristic set of enzymes, other specialized molecules and complex distribution system transport specific products from one compartment to another. If one of the organelles does not function well, most of activities and reactions inside cell could not occur. Organelles such as endoplasmic reticulum, golgi complex, lysozomes and endosomes which function in secretory and endocytic pathway could not do their tasks, go on further and not function efficiently if one of them is not functioning. Furthermore, cell processors are a series of ordered step. Then, if there is lacking even one step, the activities of the cell would be disturbed. As example, mitochondria hold a major role of organelles where it provide energy to the cell. Disturbance or abnormalities in mitochondria proteins would lead to genetic mitochondria disorder such as Parkinson.

# data[].attributes.body
Every organelles that exist are important for each cells to function well. I chose Golgi apparatus as an example if it is lack from a cell. The Golgi apparatus, or Golgi complex, functions as a factory in which proteins received from the endoplasmic reticulum are further processed and sorted for transport to their eventual destinations such as lysosomes, the plasma membrane, or secretion. In addition, glycolipids and sphingomyelin are synthesized within the Golgi. Furthermore, the Golgi apparatus serves as the site at which the complex polysaccharides of the cell wall are synthesized in plant cells. The Golgi apparatus is thus involved in processing the broad range of cellular constituents that travel along the secretory pathway.

The Golgi apparatus manufactures a wide variety of macromolecules, including polysaccharides. The Golgi within plant cells produce pectin and other polysaccharides necessary for structure and metabolism of the plant. So without the Golgi apparatus in plant cells, for example, the plants would not be able to function properly.

Moreover without a Golgi apparatus, there would be no lysosomes. The cell would not be able to digest or break down the materials left over from protein creation. This would create a lot of excess junk within the cell. If this happened, the cell wouldn’t be able to live for very long. That is because the lysosome is responsible for digesting bacteria within a cell. For example, once a white blood cell surrounds a bacterium, the lysosomes digest that bacteria.

The proteins sent to the Golgi apparatus are created in the rough endoplasmic reticulum. The ribosomes bound to the endoplasmic reticulum secrete enzymatic proteins meant for use in the body. The protein is modified within the Golgi. So without the Golgi apparatus, proteins cannot be modified. It is very important for cells to have a complete organelles so that it can function well.

# data[].attributes.body
If one of the organelles like golgi apparatus been malfunctioned, it will not help in the collection and distribution of materials made in the cell. Malfunction of the golgi apparatus will cause the harm to the body also. Achondrogenesis type 1A is caused by a defect in the microtubules of the Golgi apparatus. Achondrogenesis is a rare and severe group of genetic disorders that results in a short trunk, small limbs, and a narrow chest. It occurs when a person’s body does not produce enough growth hormone. As a result, cartilage and bone do not develop properly, causing abnormalities in the skeletal system.

Lysosomes are important cell organelles that break down the waste
materials inside the cells which can be see as the stomach of the cell . One disease that related to the malfunction of the lysosomes is the Tay-Sachs disease, what it is is basically the molecules that suppose to be broken down accumulate instead because of the deficiency in one of the lysosomal enzymes. The symptoms of the disease normally showed after several months after birth, they begin to appear as ganglioside accumulate higher and higher inside the nerve cells and will make the infants become irritable, listless and may have seizures. Blindness, deafness and paralysis follow. And sadly, affected children usually die by the age of 5. All the treatments for the disease are still considered experimental and the disease is still incurable

# data[].attributes.body
Cell is the building blocks of life because they are the basic unit for all living organisms. They play a crucial role in maintaining the organisms’ life. Cells contain components which help to regulate the processes in our body. For example, the nucleus is the biggest organelle in the cell. It stores the DNA and control the cell activities. If the nucleus is damaged, the DNA could not be stored thus, a cell will be unable to replicate. The cell will also fails to alter its genetic state or replenish mRNA and proteins. Next, the genetic makeup within the nucleus could also damage causing the cell to lose normal control of the function. Cell division could not regulate well causing the cell to continue to divide and become a neoplasm. Neoplasm is an abnormal growth of tissue caused by the rapid division of cells that have undergone some form of mutation. This problem will eventually leads to cancer.

# data[].attributes.body
If one of the organelles in the cell does not function well, the cell will not be able to function at all or effectively since each organelle in the cell contributes in their own way to make the cell functions as a whole. For example, if mitochondria does not function well, less energy will be provided to the cell hence slowing down the activity of the cell making an organism fatigue. Mitochondrial dysfunction can cause mitochondrial disease and it affects organs in the body that require the most energy such as the brain, muscles, liver, kidney, and heart. Mitochondrial disease may cause diabetes, immune system problems, blindness, and lactic acidosis

# data[].attributes.body
If an organelles in the cell does not work properly, there might cause other effects and abnormalities to another framework of system. These can lead to some problems that may affect the whole system. In example, if the red blood cells are not function well, it can lead to abnormalities such as the crescent shape of red blood cells. Thus, it can lead to the sickle cell anemia disease.

# data[].attributes.body
Every organelles in every cells have their own specific function and very essential for the activities of the cell. If one of the organelles does not function well, the whole activity of the cell will be disturbed and eventually it will effect the whole metabolism of the body. For example protein produced by the ribosomes needs to be further modified inside the RER, if the RER can't function well, proteins like enzymes might not be produced at the right amount.

# data[].attributes.body
Every organelles have their own function in the cell. If one of the cell cannot function well it will disturb the cell activities. For example, if the ribosome does not function well, then protein cannot being translated. Same goes to mitochondria which may bring disaster if cannot function well as it is the site for energy production. Disfunctional Golgi body will cause the cell product cannot being sort, pack and transport to other part of the body. Same goes in plant cells, if the chloroplast cannot function well the plant cannot undergoes photosynthesis.

# data[].attributes.body
Not all organelles found in the cell are needed in every system in the body to function. Only prime organelles such as nucleus and mitochondria is essential for most if not all, for the cell to function. Nucleus functions to regulate activity of the cell whereas mitochondria provides energy for the cell to work.

Each cell in the body contains and requires dozens of the mitochondria to function. Mitochondria is a tiny capsule shaped structure which is known as the powerhouse of the cell. mtDNA is maternally transmitted. Mitochondria contains more than 13 protein and vast amount of protein from the nucleus itself. Many of genetic mitochondrial disorders are caused by mutations the nuclear genome.

Abnormality occuring within the mitochondria will result in fatigueness, weakness of the locomotion system and difficulties of breathing may occur. Abnormality of the mitochondria's protein and other molecules are linked to major diseases like Parkinson's and Alzheimer's disease. It depends on where the mitochondria disease occur as they will also result in muscle weakness and pain, digestive problem and also seizure

# data[].attributes.body
Core organelles are found in virtually all eukaryotic cells. They carry out essential functions that are necessary for the survival of cells – harvesting energy, making new proteins, getting rid of waste and many more. Core organelles include the nucleus, mitochondria, endoplasmic reticulum and several others. I would like to discuss about ribosomes which are the protein-building factories in all cells. Living cells use proteins for structural units, as transportation mechanisms between the interior and exterior and as specialized chemical catalysts called enzymes. Without ribosomes, no proteins would exist to perform those tasks, or any of the many other jobs that proteins do. A cell without ribosomes would not be able to survive.

The dysfunction of the ribosomes will cause a disease called ribosomopathies. It is a disease that compose a collection of disorders in which genetic abnormalities cause impaired ribosome biogenesis and function, resulting in specific clinical phenotypes. (Ribosomopathies: Human disorders of ribosome dysfunction.)Abnormal ribosome biogenesis is linked to several human genetic diseases, particularly inherited bone marrow failure diseases, which are characterized by a predisposition to cancer and a reduced number of blood cells. Such as t Diamond–Blackfan anaemia (DBA), Dyskeratosis congenita (DKCX) and Treacher Collins syndrome (TCS).

Besides, other organelles such as Mitochondria is also important as it is the power house of the cell, as it provides with energy to the cell and if it is not present in cell the cell will not be provided with energy. Next, if there is no nucleus then the action and works of cell will be not maintained properly as nucleus is the the head of the cell. Lastly, if golgi apparatus is not present then it will not help in the collection and distribution of materials made in the cell. Achondrogenesis type 1A is caused by a defect in the microtubules of the Golgi apparatus. Achondrogenesis is a rare and severe group of genetic disorders that results in a short trunk, small limbs, and a narrow chest. It occurs when a person’s body does not produce enough growth hormone. As a result, cartilage and bone do not develop properly, causing abnormalities in the skeletal system.

This shows that all organelles in our body are equally important and each organelle have its own function and sometimes related to each other. Each organelles carry out specific functions to help the organism to function properly.

# data[].attributes.body
For an example, if the ribosomes were not working properly then our cell would not be producing proteins. If one of the cell did not produce proteins enzymes would not be available to speed up reactions throughout the body, and they would also not be available to make the many organelles made with proteins such as microtubules which would cause many other problems within the cell. That's why each organelle have its own function and sometimes related to each other.

# data[].attributes.body
An organelles is vital cellular structure in eukaryotic cells analogous to an organ in the body.Organelles are discrete structures within the cell that perform a specialized function.Examples of organelles are lysosomes,nucleus,golgi and ribosomesIf the ribosomes does not functioning properly,the cell would not be producing proteins.If the cell did not producing protein,the enzymes would not be able to speed up the reaction throughout the body,and they also would not be able to make the many organelles made with proteins such as microtubules which would cause many other problems within the cell.Same goes to if the Golgi apparatus does not working well the protein would not be packaged which would not allow lysosomes to have digestive enzymes inside that can cause a build up of materials.Lysosomes are important organelles that break down the waste materials inside the cells.One disease that can related to the malfunction of lysosomes is the Tay-Sachs disease.

# data[].attributes.body
All organisms are made up of cells and each cells consist of organelles. Each organelles carry out specific functions to help the organism to function properly. These organelles need to interact or communicate with each other to perform its functions. However, if one of the organelle fails to perform its task, it will cease to function causing the body systems to malfunction which might be fatal.
The Endoplasmic Reticulum (ER) helps to produce the protein necessary for cell life. If the Golgi apparatus fails to function, the produced materials cannot be transported from the cell while the malfunction of Lysosomes will cause the death of cells due to infections. The failure of function of Mitochondria causes the organism to have no energy to perform their functions.

# data[].attributes.body
All organisms are made up of cells and each cells

# data[].attributes.body
Cell is the building blocks of the organisms. Each organisms and living things consist of organelles which function as compartmentalization in the cell. Each organelles in the cells perform specific function which enable the organisms to function well. Therefore, if one of the organelles in the cell does not function well, the organisms will either fatal or their body system will not perform well.

One of the important organelles in the cells is endoplasmic reticulum. Endoplasmic reticulum are divided into two types which are rough endoplasmic reticulum and smooth endoplasmic reticulum. Both types of endoplasmic reticulum carries the important functions towards the organisms body. For example, the function of rough endoplasmic reticulum is synthesis of large, complex proteins and amino acids. The membranes of RER is lined with ribosomes. Therefore, RER is very important in synthesizing protein from the ribosomes. Other than that, smooth endoplasmic reticulum are also functioning in synthesizing lipids and it produces phospholipids and cholesterol that help to stabilize the membranes of the entire cell. In a conclusion, if the ER is not function well, protein and lipid cannot be synthesize. Moreover, without ER, the substances such as protein cannot be transported to the Golgi apparatus and it would not be able to modify these proteins ,thus make our body lack of enzymes and would not break the things down fast.

# data[].attributes.body
Membrane-enclosed compartment or organelles in all eukaryotic cells are a specialised structure of a cell and has its own specific functions. The absence or the malfunction of one of the organelles in the cell would cause the whole activities of the cell interrupted, next disturbed the body system which leads to various body damage and diseases. For example, ribosomes plays an important role in make proteins from all amino acids. If ribosomes does not function properly, it will cause no protein synthesis. The malfunction of ribosomes caused by mutations in other genes required for normal ribosomes. The dysfunction of the ribosomes will cause a Ribosomopathies disease, which is a disease that compose a collection of disorders in which genetic abnormalities and cause impaired ribosomes biogenesis and function, resulting in specific clinical phenotypes. Ribosomes malfunction also can cause cancer and other serious disease that can bring to fatal.

# data[].attributes.body
Ribosomes are the building - protein factories in all cells . A cell without the ribosomes will not able to survive because no protein will exist and many mechanisms can not perform without the protein . As we know , protein is the structural unit and use as the transportation mechanism between interior and exterior and has specialised chemical catalyst called enzymes . Any given cell can have hundreds of different protein , and all the proteins are built by the ribosomes . If there is no ribosomes , or ribosomes is not functioning weel , the information from the messengger RNA could not be read . It will be hard to assemble the right amino acids in order to get specific protein .
Protein also generating the electrical signal which is every action that we make, we are depend on protein's work in our body . Wihtout the protein , the chemistry inside the cell becomes comes to a halt . Lastly , wihout the chemical reaction within the cells , there is no life .

# data[].attributes.body
Lysosomes are important cell organelles that break down the waste materials inside the cells which can be see as the stomach of the cell but what if there is some malfunction in lysosomes, what will happen to the cell? One disease that related to the malfunction of the lysosomes is the Tay-Sachs disease, what it is is basically the molecules that suppose to be broken down accumulate instead because of the deficiency in one of the lysosomal enzymes. The symptoms of the disease normally showed after several months after birth, they begin to appear as ganglioside accumulate higher and higher inside the nerve cells and will make the infants become irritable, listless and may have seizures. Blindness, deafness and paralysis follow. And sadly, affected children usually die by the age of 5. All the treatments for the disease are still considered experimental and the disease is still incurable.

# data[].attributes.body
Malfunctioning Mitochondria Cause Many Disorders. Cells that have no mitochondria are unable to convert oxygen into energy, found in the form of adenosine triphosphate (ATP). All multicellular eukaryotic organisms, including plants and animals, have mitochondria in some cells, but prokaryotes and some single-cell eukaryotes do not have mitochondria.Mitochondrial diseases are caused by abnormal genes that lead to flawed proteins or other molecules in the mitochondria. The various subtypes are caused by alterations in different genes, leading to worn-down cells in different parts of the body. Hardest hit are organs and tissues that need a lot of energy, like muscles, brain, heart, kidneys and liver. When the energy supply slumps, cells can become damaged or destroyed. Humans also need mitochondria to produce cholesterol and a component of hemoglobin. Even if cells were able to produce enough energy using anaerobic glycolysis, it is likely humans would still not be able to survive without mitochondria to help regulate these functions.

# data[].attributes.body
A cell consists of different types of organelle that work together to perform efficiently. Every organelle has their own specific task for cell functioning and if one organelle is not functioning, it will affect the whole cell. Mitochondria is one of the most important organelle in cell. It is known as the cell's powerhouse in metabolic activities as it helps to supply energy. The energy exists in the form on ATP, adenosine triphosphate. Energy is vital for muscle contraction in movement. The specialized ER of a muscle fiber, sarcoplasmic reticulum, stores calcium ions and when they are released, they cause contraction. During active transport into the sarcoplasmic reticulum, calcium ions level in the cytoplasm drops cause muscle contraction to cease. Active transport requires ATP to work. The cytoskeletal elements, microfilaments, are made up of actin, and the associated proteins, such as myosin. These various proteins form sarcomeres, the functional units of muscle cells. They contract and cause the muscle cell shortens. If mitochondria is not functioning, it will cause trouble in producing ATP, hence, lead to the failure of active transport of calcium ions into sarcoplasmic reticulum. This failure will cause muscle cell to not contract and shortens. When muscle is unable to contract, it will disrupt one's movement.

# data[].attributes.body
Organelle is the structure in the eukaryotic cells that conduct specific functions. Each of this organelles perform their own task to help the cell functioning. Some of this organelle is linked to each other,for example Golgi apparatus and vesicle transport . If one the organelle not function well,it will disrupt the other function of organelles. We take example of Golgi apparatus. If Golgi apparatus does not function well, the product of Golgi apparatus cannot be produce. The protein that Golgi apparatus suppose to sort,modify and packaging would staying there,nowhere to go. This will cause the cells and organ that needed Golgi apparatus product not functioning . When the vesicle transport not functioning , the product of Golgi apparatus also cannot be transported to outside of the cells.Nothing is distributed to other part of the cells. One of the disease can happen to human when Golgi apparatus not working is Achondrogenesis Type A. This happen when not enough growth hormone produce due to Golgi body do not transport it ( hormone is also made up from protein) .This disease cause the newborn baby have narrow chest(cause baby hard to breath), short limb and skull bone soft and easily break rib.

# data[].attributes.body
Each organelle have their own specific funtions which is to undergo some processes in the cell.If any one of the organelle does not function well,the process that occur in the whole cell will be affected also.
Rough Endoplasmic Reticulum(RER) is in the section on ribosomes and is very important in the synthesis and packaging of proteins. RER plays an important role in protein synthesis.The process of protein synthesis starts when mRNA moves from the nucleus to a ribosome on the surface of the RER. As the ribosome builds the amino acid chain, the chain is pushed into the cisternal space of the RER.If the RER does not function well,proteins are incomplete, they does not collect and the RER not pinches off a vesicle. That vesicle, a small membrane bubble, cannot move to the cell membrane or the Golgi apparatus. Some of the proteins will cannot be used in the cell and some will cannot be sent out into intercellular space. This will affect the whole protein synthesis process in the cell.

# data[].attributes.body
Each of the organelles in the cell has their own specific function. If one of the organelles in the cell does not function well, it will resulting in the bad effect to the organism itself.

For example, if the rough endoplasmic reticulum does not function well or does not working well, the proteins cannot be transported to the Golgi apparatus. These proteins also cannot be modified by adding fats or sugars and folding them. If this happen, our body are unable to break things down fast enough and will lead to build up of materials. Besides that, if the mitochondria in the cell does not function well, there will no energy will be produced which then will cause fatigue and muscle soreness.

# data[].attributes.body
Organelle plays an important role in the regulation of cell for all organisms and living things. If one of the organelles in the cell does not function well, it will bring adverse effects as every each of the organelle has its own specific function which operate like organs by carrying out specific tasks.

For example, the nucleus. The presence of a defined nucleus distinguishes a eukaryotic from prokaryotic cell. The function of nucleus is to control all cellular activity and contains the cell’s genetic information. If the nucleus does not function well, the cell division might not occur as the nucleus contain DNA which arranged into a compact structure known as chromatin that is involved to form chromosomes during cell division. When there is no cell division, new cell cannot regenerated and cell reproduction or even growth will not take place. Thus, the cell's life cycle cannot be maintained and eventually the cell would die when all the synthesis does not occur.

# data[].attributes.body
Every organelles have its own specific function. If one of organelles does not function well or stop functioning, the cell will die and cause fatal for organisms. For example, nucleus. As we know nucleus controls the cell metabolism, division and others. If its fail to function, the cell will lose control and cell will continue undergo division process and cause neoplasm. Neoplasm can be non-cancerous (benign), pre-cancerous (pre-malignant) or cancerous (malignant). Abnormal cell growth may cause cancer such as leukemia. Benign do not become cancer and are usually life threatening. Pre-malignant have not become cancer but it have potential to become cancerous. Malignant is the neoplasm which has cancerous such as leukemia due to the abnormal cell growth.

# data[].attributes.body
in cells, each organelles plays its own specific function. however, their function are related to each other. for example the process of extracellular enzyme synthesis. during this process, nucleus, endoplasmic reticulum, ribosome, transport vehicle, golgi apparatus, secretory vehicle and cell membrane are involved. if one of the organelles involved in this process does not function, the enzymes cannot be synthesized. thus, every organelles must be function well in a cell to ensure the cell can function well to our body.

# data[].attributes.body
If the nucleus failed to work, then immediately the cell would cease to function because no direction or synthesis would be available. The ERs handle, at least in simple terms, protein production necessary for cell life. If the Golgi stopped, all of the cells produced material would build up in the cell and nothing could be transported from the cell, ending in collapse. Lysosomes protect and destroy foreign or unwanted substances, so those ceasing would probably end in the cell dying of an infection or foreign problem. The vacuoles are not organelles but are simply small bubbles of membrane used for transport, they bring in necessary substances from the outside of the cell using glycoproteins. Chloroplasts are in only plant cells, and give the cell energy- without them, no energy to do things. Same goes for mitochondrion, except they can be in both animals and plants. Cytoskeleton is necessary only in animal cells and without it the cell would collapse and cease to function. The cilia/flagella regulate movement, and although they are not necessary to the cell directly, and although they are not always on cells, they could have a negative effect if the cell could not get to its needed location.

# data[].attributes.body
Organelles can be classified as nucleus, smooth endoplasmic reticulum, rough andoplasmic reticulum, golgi apparatus, lysosomes, mitochondria, and chloroplast. They have their own specific function to make sure that the cycle of the cells run well. If one of the organelles do not function properly, it might cause fatal or disease.
For an example, rough endoplasmic reticulum. This organelles plays a large role in the synthesis of large samples proteins and amino acid. The membranes of an rough endoplasmic reticulum is lined with ribosomes. If the main function of rough endoplasmic reticulum collapsed, the transportation of substances such as proteins will not proceed to the Golgi Apparatus. It is also, would not be able to modify protein by adding fats or sugars and folding them. Our body also will lake of enzymes and we would not be able to break things down fast enough as normally. Disfunction of the endoplasmic reticulum can caused by genetic mutations, aging, also environmental factors. This can cause various disease such as, neurodegenarative disorder like Alzheimer's disease, Parkinson's disease, bipolar disorder. In addition, it also can cause diabetes and inflammation.

# data[].attributes.body
Each organelles have its specific function that might cause fatal if the organelle cannot function properly. As an example, mitochondria are the “power houses” of the cell, for they release food energy for cellular respiration with the help of enzymes. The structure of a mitochondrion is an inner and outer membrane (the inner membrane is folded into cristae). The number of mitochondria in a cell varies depending on the type of cell. A larger number of mitochondria is found in muscles, or where energy is most needed. The mitochondrion malfunctioning would not allow the release of food energy into the cell. In places with many mitochondria such as muscles, it may not allow things to move.

# data[].attributes.body
Each organelles have its owns specific functions. If one of the organelles does not function well it will change the process and the system in the cell. For example, mitochondria plays an important role in the cell by supplying energy ATP. If mitochondria does not function well it will affects the cell activities and can cause the affected person to feel fatigue, muscle weakness, seizure and pancreatitis. Heart, muscles,brain and lungs that required greatest amounts of energy are also affected. Besides, dysfunctional mitochondria lead to most of cell dysfunction and can cause death as there are no more energy supplies to conduct chemical reaction and movement in and outside the cell.

# data[].attributes.body
Since organelles are a specialised structure of a cell and performs  specific  functions, the absence or the malfunction of one of the organelles in the cell would cause disruption of the organelles’ tasks. The malfunction of smooth endoplasmic reticulum, for example will cause no detoxification of substances and no production of fats. The malfunction of DNA, nucleolus and ribosome will stop proteins from being produced, as DNA gives out instructions for proteins to be made and without a nucleolus, ribosomes that produce proteins  would not be present. This is an example of how a single activity in a cell affects the other activity, and how one process comprises from another. Another is the role of the rough endoplasmic reticulum in which without it functioning properly would cause no transportation of protein to the Golgi apparatus and no modification of proteins will happen. This will also affect the synthesis of enzymes later on. If a vacuole does not carry out its function as the storage space then the whole cell will be build up. The failure of the centrioles will not allow the cell to divide and chromosomes to separate since there will be no spindle fibres formed. If the cytoskeleton does not work, the cell will lose its structure and the organelles inside will not be in place meanwhile the malfunction of mitochondria will lead to no production of energy. The malfunction of one of the organelles in the cells can also lead to serious health problems.

# data[].attributes.body
Organelles are differentiated components that have their own function respectively.  Each of these organelles has to function properly so that the activities of the cell are not interrupted and also to avoid any disease. If one of the organelles is not functioning well, the individuals might diagnosed with diseases that is going to be for rest of their life. For example, dysfunctional mitochondria. This will lead to mitochondrial disease that caused by two possible factors. The first one is mutation occur onto the mitochondrial DNA which affects the function of the mitochondria while another factor is mutation in the genes of the nuclear DNA where the genes are transferred into mitochondria. Examples of mitochondrial diseases are diabetes mellitus and deafness, Leigh syndrome and mitochondrial myopathy.
Meanwhile, symptoms of mitochondrial disease are unable to coordinate muscle properly, muscle weakness, poor growth, visual and hearing problems, heart diseases, liver diseases and neurological disorders.

# data[].attributes.body
Eukaryotic cells have within them a variety of different structures called organelles. Organelles are specialized structures of the cell that perform specific function and enclosed separately within its own lipid bilayer. Organelles also are the cell parts that are adapted and specialized to perform various vital activities of the cell same goes to the organs of the human body. If one of the organelle is not functioning well, then the whole activities of the cell will interrupt. For example, nucleus, the most important organelles in cell. Nuclei contain genetic material called DNA that is responsible for controlling and directing all cell activities. Nucleolus is small structure found within the nucleus that functions to produce ribosomes for the cell. If nucleus is not functioning well, there will be no instruction for making proteins so none would be made and no ribosomes would be made. So, in general, the cell needs the help of organelles to function well and without organelles, the whole cell will collapse.

# data[].attributes.body
An organism begins with a single functional cell. A cell can function well only when the organelles work properly and do their tasks efficiently. For an example, nucleus is vital in the cell as it controls the coordination of cell activities and also contain the blueprint of the cell (hereditary material). If the nucleus cannot function well, all activities such as the cell division and protein synthesis do not occur. Other than that, if the Golgi apparatus of the cell is not function, the modification, packaging and transportation of protein cannot be occur and this may cause a lot of damage into the body system as protein is one of the most important substance that is used as enzyme for example. Lack of enzyme will disable all the body function or any chemical process in the body. Therefore, we can conclude that functional organelles are very important and if one of the organelles are not function well, the body system will be disturbed which leads to various body damage and diseases.

# data[].attributes.body
Each of the organelles in the cell has their specific role so that the whole cell can function well. if one of the organelles does not functioning well, it will interrupt the whole cell activities. For example, if the nucleus is not functioning. As all known, the function of nucleus is to control all the cell activities. Inside its fully-enclosed nuclear membrane, it contains the majority of the cell's genetic material. This material is organized as DNA molecules, along with a variety of proteins, to form chromosomes. If nucleus were to shut down, the genetic makeup located within the nucleus could also suffer damage on its own. In this case, it often causes the cell to lose normal control of the function that regulates cell division, causing the cell to continue to divide and become a neoplasm.

# data[].attributes.body
Organelles are specialised subunits that has specific functions within either prokaryotic and eukaryotic cells. If one of the organelles does not function well, the activity of the whole cell will be affected as they associate to one another. For an instance, mitochondria functions to synthesize energy or ATP for the cells. If there is any malfunction, the energy needed for other cell activity will not be able to be produced hence affecting the cell integrity. Ribosomes is another important organelles which helps in making proteins. If ribosomes fail to function, proteins and RNA cannot be synthesized which resulting in many possible diseases. Next is lysosomes which play roles to protect and defend against foreign or unwanted substances. The cell will be easily attacked and destroyed by foreign bodies or unwanted substances such as in immune system. In plant cells, performance of photosynthesis will be affected if chloroplast cannot function well. This is because the main role of chloroplast is to absorb sunlight and convert it to chemical energy which triggers the plant to produce its own food.

# data[].attributes.body
Every cell  in the body contains organelles which have their own specific function in helping cell function well as a whole. Organelles are divided into two types which are core organelles and specialized organelles. Core organelles are organelles which exist in all eukaryotic  cells. They carry out essential functions that are necessary for the survival of cells such as harvesting energy, making new proteins, and getting rid of waste. Core organelles include the nucleus, mitochondria, endoplasmic reticulum and several others. Specialized organelles only exist in the cell which need them and not all type of cell have the same need. Several examples of these specialized organelles are chloroplast and vacuole. The malfunction of organelles can caused malfunction in cell as  they have the interaction in the synthesis of proteins and other functions. The damage of the cells will lead to many diseases. One of the disease caused by the malfunction of the cell organelles is Tay-Sachs disease. This disease occurs as the result of the malfunction of lysosome. The molecules that suppose to be broken down accumulate instead because of the deficiency in one of the lysosomal enzymes. This disease happened in infants and usually the children which affected by this disease only able to live until five years old. There are also another diseases caused by the malfunction of another organelles.  Most of these diseases will end to disability or death of the person affected.

# data[].attributes.body
Cell is the basic unit of life. There are organelles that specialized the structure of the cell which will perform specific function in the cell. If one of these organelles in the cell not functioning well, it will interrupt the whole process in an organism. Cytoskeleton filaments, golgi apparatus, cytosol, endoplasmic reticulum, nucleus, mitochondria and centriole are some of the example of organelles. For instance, if cytoskeleton filaments (play role in cell motility) stop functioning well, none of organelles can be move to the another part of the cell. Thus, mitosis and cell division can’t be run.

# data[].attributes.body
If one of the organelles in the cell does not function well, the life functions or processes of human and other organisms will be disrupted. Organelles that involved in the process of digestion, cell reproduction, growth, protein synthesis and intermediary metabolism are mostly lysosomes and nucleus. Lysosomes contain hydrolytic enzyme that helps in breaking down complex molecules to simpler molecules. Therefore, the dis functioned of this organelle would definitely causing the rate process of digestion or other life process to decrease. However, the question that matters is why the enzymes do not destroy the lysosomes that are present in them? Nucleus acts as the major control centre of the other cell and contain DNA which directs the synthesis of proteins by the cell and that is why if nucleus does not function well, all of the other cell activities are slowing down. Next, ribosomes is responsible for the synthesis of proteins. Yet, if ribosome is not doing their function properly, protein will not be able to sort out fully for long period of time instead it causes swelling of cell. In addition, cell membrane helps in selectivity in regulate the materials moving to and from the cells. If this organelle does not functioning, other cells will enter and destroy the good cells inside the body especially pathogen. Besides humans or animals, plants also being affected by the dis functioned of organelles.For instance, chloroplast helps in the process of photosynthesis as it contain chlorophyll that helps in trapping the light. If the disruption of the chloroplast occur, the plant will not be able to conduct photosynthesis in a fast rate. Lastly, plants has contractile vacuole. The contractile vacuoles functioning in stores and digests food. If the organelles is not functioning well, the storing and digesting system will be interrupted and causes slow growth rate of plant.

# data[].attributes.body
Organelles is one of several structures which has specialized function, suspended in cytoplasm of an eukaryotic cell. Nucleus, endoplasmic reticulum, and golgi apparatus are some examples of organelles. If one of the organelles does not function well, it will affect the whole cell activities. For example, If the nucleus failed to work, then immediately the cell will stop functioning because no direction or synthesis would available. The other example of organelle is endoplasmic reticulum (ER). Endoplasmic reticulum function as the protein synthesis. If the ER was failed to function, the protein can’t be synthesis. Golgi is functioning in packaging and transporting the protein that have been synthesized. If Golgi body stopped, all of the cells produced material could not be transported from the cell. Lastly, all organelles have their specific job that allow cell to be functioning well. If one of them not functioning, so the whole cell will collapse.

# data[].attributes.body
If one of the organelles do not function well, the overall system of the cell will be disrupted hence lead to cell fatal. For example, if nucleus that is responsible for the coordination of cellular activities cannot function, there will be no ribosomes produced to read the messenger RNA and therefore no polypeptide chains of protein can be synthesised. This is due to the nucleolus inside the nucleus as the site of ribosome synthesis.  So if no proteins are produced then there will be no enzymes being synthesised. The cell will die without any protein synthesised. The defective nucleolus can lead to neurodegenerative disorder like Alzheimer’s disease. If mitochondria which act as the site of energy production do not function well, there will be no ATP energy production. Besides energy production, malfunction of mitochondria will disrupt steroid synthesis process and cholesterol metabolism.  One of the examples of mitochondrial diseases are Myoclonic Epilepsy with Ragged Red Fibers (MERRF syndrome).  There will be lumps of diseased mitochondria accumulating in the subsarcolemmal region of the muscle fiber and appear as "Ragged Red Fibers". This syndrome will cause poor night vision and also hearing loss.

# data[].attributes.body
Lysosomes are important cell organelles that break down the waste materials inside the cells which can be see as the stomach of the cell but what if there is some malfunction in lysosomes, what will happen to the cell? One disease that related to the malfunction of the lysosomes is the Tay-Sachs disease, what it is is basically the molecules that suppose to be broken down accumulate instead because of the deficiency in one of the lysosomal enzymes. The symptoms of the disease normally showed after several months after birth, they begin to appear as ganglioside accumulate higher and higher inside the nerve cells and will make the infants become irritable, listless and may have seizures. Blindness, deafness and paralysis follow. And sadly, affected children usually die by the age of 5. All the treatments for the disease are still considered experimental and the disease is still incurable.

# data[].attributes.body
Organelles are the structures that have specific functions in order to help the cell function well. The Golgi body, lysosomes and mitochondria are all examples of organelles.If one of the organelles in the cell does not function well, it will lead to fatal. For example, if the Golgi body stop functioning, the proteins cannot be packaged, which do not allow lysosomes to have hydrolase enzymes inside and cause a build up of materials in the cell. Transportation from the cell is not available, ending in collapse. Lysosomes function in protection and destroying foreign or unwanted substances. Without lysosomes,the cells will not be able to defend themselves against the  foreign bodies. It will be hard for the cells to digest excess or worn out organelles, food particles, and engulfed viruses or bacteria.The failure of mitochondria lead to fatigue and muscle soreness because no energy is produced. The cell will not have its respiratory function such as carbon dioxide, water and energy in which the cell will die with no energy and nutrients.

# data[].attributes.body
Organelles are number of organized or specialized structure that have their own roles within a eukaryotic cell. If one of the organelle cannot functioning well, it will affect the cell activities. For example, if chloroplast in the plant cell cannot functioning well, work to convert light energy from the sun into sugar cannot be perform. If this happen, there are no production of energy, so the plant would die.If the ribosomes were not working properly then cell would not be able to produce proteins. If cell cannot produce proteins, the enzymes would not be available to speed up reactions throughout the body, and they would also not be available to make the many organelles made with proteins such as microtubules which would cause many other problems within the cell.

# data[].attributes.body
If Golgi apparatus does not function well, the proteins would not be packaged which would not allow lysosomes to have the digestive enzymes inside which would cause a build up of materials. Secretion would also not be possible because the Golgi would create secretory vesicles.

# data[].attributes.body
If let's say golgi apparatus in our body are not functioning anymore, it is in the context of Alzheimer's disease. The major function of Golgi apparatus is to modify, store and package proteins for cell secretion, but if Golgi apparatus is implicated in aging of an Alzheimer's patient, the Golgi apparatus would fall apart. Secretion could not be done, proteins are sent to the wrong locations and alteration of the synapses happens.  Amyloid plaque would be formed in the brain - plaque that kills cells and contributes to memory loss, trouble understanding visual images and other Alzheirmer's symptoms.

# data[].attributes.body
If the cytoplasm in our cell does not function well,it will create the problem to our body.This is because, cell activities would not be able to take place since the cytoplasm is where cell activities take place.All of the organelles wouldn't stay in the same place.Next, the plant would not be able to survive because the cytoplasm is the parts of a cell that are enclosed in the plasma membrane. It would be like us without a live or spleen.Cytoplasm is the fluid within the cell, but it is very glutinous due to the presence of multitudinous proteins, sugars, amino acids and other organic compounds, not to mention billions of ions like K+ and Na+. The processes undergone in the cytoplasm are uncountable. Glycolysis the precursor of the energy-giving reactions of aerobic respiration occur in the cytoplasm.Ribosomes are drifting about as are tRNA molecules with attached amino acids and all this for translation (production of protein) which can occur free in the cytoplasm. So without a cytoplasm,all these activities cannot be done.

# data[].attributes.body
Organelles are found in all eukaryotic cells. they carry out vital functions that are needed for the cell to survive. The nucleus, as the control center of the cell, regulates functions in the cell. a cell cannot reproduce or communicate with other cells. A cell without control and internal coordination cannot survive longer. Mitochondria converts oxygen and nutrients into ATP (adenosine triphosphate). Without mitochondria, the metabolic functions cannot be performed. cholesterol and a component of haemoglobin cannot be produced without mitochondria. If cytoskeletons were absent, the cell will have no structure and not stable. if the Golgi stopped working, secretion would not be regulated because secretory vesicles were created at the Golgi. The protein would not be packaged and caused a build of materials inside because the lysosomes are not allowed to have the digestive enzymes.

# data[].attributes.body
Organelles are in charge to carry out specific functions in order for a cell to operate. For example, if the nucleus fails to perform it's function, then immediately the cell would cease to function because no direction or synthesis would be available. If the Golgi stopped, all of the cell's products would build up in the cell and nothing could be transported from the cell leading up to a blockage. Lysosomes are responsible for the immunity of a cell as they protect and destroy foreign or unwanted substances, so those ceasing would probably end in the cell dying of an infection or foreign problem. If the mitochondrion fails to function, no energy in the form of ATP would be produce which would cause the cell to die as processes such as cellular respiration is cut off. Overall, every organelle no matter how big or small, plays an important role in sustaining a cell's lifespan.

# data[].attributes.body
Nucleus is known as the brain of the cell which control all cells activities, thus if it is not functioning well it will cause misinformed and dysfunctional of other cell. Next , if the ribosomes is not  working properly no protein will be produced. Protein enzyme will not available to speed up reaction through the body. Then, if rough endoplasmic reticulum cannot function well it, substances especially protein cant be transported to the Golgi Apparatus and by preventing the transportation our body would lake enzymes and we would not be able to break things down fast enough which would cause a build up or materials. Next, if Golgi Apparatus is not functioning well,the protein will not be packaged and will not allow lysosomes to have its digestive enzymes inside which cause the build up materials. If lysosomes and vacuole is not functioning well , it will cause the build up of materials. For mitochondria , no energy will be produced thus caused fatigue and muscle soreness . For conclusion , every organelles have important roles that if one of them is not functioning well , the whole progress of cell will be disturbed and will cause other problems.

# data[].attributes.body
Nucleus is one of the cellular organelles that found in eukaryotes . Prokaryotes do not have DNA contained in a nucleus . The function of nucleus is to contol the all the activities in the cell , regulate gene expression , controls cellular growth and replication . If nucleus does not function well , thus the other organelles stop functioning because nucleus is the control center of the cell . Without nuclues , the other organelles will stop doing their part such as the cell membrane, it will start letting in substances in that are not suppose to go in . Next , the ribosomes will stop making proteins and the centroiles will not be able to divide and reproduce cells . Plus , there would be no energy because the mitochondrion wouldn't be able to turn glucose into ATP. The DNA contained in a nucleus is tightly packed into chromosomes, which must be unwound prior to cell division and DNA replication. DNA transcription into mRNA takes place in the nucleus. If the nucleus is not functioning well , there will be no transcription of DNA into mRNA . But in some other cases , nucleus is not necessarily present in some cells . In many multicellular organisms, such as humans, the nucleus is removed naturally and is normal for the function of a particular cell. Two examples of this are human red blood cells and platelets. Since these cells do not contain a nucleus, they are unable to replicate.But they are produced in bone marrow . Other cells may contain multiple nuclei. This phenomenon is seen in some protozoa and fungi.

# data[].attributes.body
As we know that cell is a basic unit of life and it is vital for living things to keep functioning. To allow cell to do the work, it has many organelles inside it and if one the organelles in the cell does not function well, it will affect the activities inside the cell. For example, if the nucleus which is the organelle that control all the activities in the cell is not functioning, eventually the whole system inside the cell will be disturbed. Moreover, imagine if ribosome is the organelle that is not functioning well, literally the process of making protein cannot be done. Same goes to the rough endoplamic reticulum that is responsible for the lipid and protein synthesis, if it does not well functioning, eventually the whole process the related to lipid and protein will be left abandoned.

# data[].attributes.body
The Golgi apparatus is an organelle that can be found mostly in eukaryotic cells. It is made up of membrane-bound sacs, and is also called a Golgi body. The Golgi apparatus is to process and bundle the macromolecules such as proteins and lipids as they synthesized within the cell. It also compared as a post office inside the cell since one major function is to modify, sort and package proteins to be secreted. If the Golgi apparatus is not function well in the cell, the protein will not be packaged and lysosome will not allow to get the digestive enzyme inside that build up the materials and the lipids cannot be transport throughout the cell. Moreover, there will be no secretion of the secretory vesicles. Next, it will disturb some reaction such as the enzymatic secretion, some oxidation reaction, some types of metabolic transportation and electron transfer may be affected.

# data[].attributes.body
The function of Rough endoplasmic reticulum is to synthesize protein .There is part of RER conducted the process of glycosylation for the protein . It will form glycoprotein for the proper folding and help the protein to reach the binding site of it .If the process of glycosylation does not work properly , there will be a mutation of the glycoprotein because of the partial glycosylation in the RER will affect the order of glycoprotein for binding to it's site. This will affect the organ in the body system which is inherited disorder. There is one type of glycoprotein which is the N-linked glycoprotein. When the absence of N-linked glycoprotein in the RER ,it will inhibit the implantation of the embryo .

# data[].attributes.body
Every organelles in the cell have their own roles and its really important to the cell to functioning well. Even only one of the organelle are not functioning well,it may effects the whole cell as every organelle needs the others organelles to do their jobs properly. As example, rough endoplasmic reticulum play important biological roles in the protein biosynthesis and lipids. The ribosomes surround that attached to the RER will undergoes the translation of RNA to synthesis the protein. Then, the protein will be transfer to golgi complex in the form of transport vesicles to undergoes the process of sorting, packaging of proteins and will end with the transport of protein to the target. So we can see that each of organelles are related to each others to accomplish their jobs. So,if one of the organelle did not functional well,the protein might be not synthesis and might not even be transport to the target cell. When the protein cannot be transport,how can our body can functional well as most of the activities in the cell need protein to undergoes the process well.

# data[].attributes.body
Rough endoplasmic reticulum has ribosome on its outer surface which involve in synthesizing of protein in the cells. The rough endoplasmic reticulum is a place where the protein that gets into the reticulum is being translates, modify and transport to the Golgi apparatus. When the rough endoplasmic reticulum does not function well, the process of modifying the proteins by adding fats or sugar will not be able to happen. Hence protein would not be transported to the Golgi apparatus. Without this transportation, our body will have insufficient enzymes that act as a catalyst and will lead to very slow rate of breaking down substances.

# data[].attributes.body
The cytoskeleton plays crucial roles in keeping the structure of the cell shape, in providing the stability and motility of the cell, and movement of organelles within a cell. It runs all around the cytoplasm and around the nucleus. Plus, microtubules are what the mitotic spindle is made of, therefore without them cells would not be able to divide. The cell would die and collapse under its own weight. Besides, there is no track for the chromosomes to move during mitosis. Which means that if the chromosomes don't complete mitosis and the cystoskeleton is malfunction to divide the cell during cytokinesis, the cell will never exist anymore. Cells need to be able to divide or injuries would never heal. Without cystoskeleton, cell will no longer be able to retain its shape and will ultimately burst. The cell's movement also would interfere with the body movements of the organism and could cause to serious diseases which is neurodegeneration such as Alzheimer's Disease and Parkinson's Disease.

# data[].attributes.body
Lysosomes are important cell organelles that break down the waste materials inside the cells. If there is some malfunction in lysosomes, One disease that related to the malfunction of the lysosomes is the Tay-Sachs disease will occur. It is basically the molecules that suppose to be broken down accumulate instead because of the deficiency in one of the lysosomal enzymes. The symptoms of the disease normally showed after several months after birth, they begin to appear as ganglioside accumulate higher and higher inside the nerve cells and will make the infants become irritable, listless and may have seizures. Blindness, deafness and paralysis follow. And sadly, affected children usually die by the age of 5. All the treatments for the disease are still considered experimental and the disease is still incurable. (58666)

# data[].attributes.headline
58682 -Khairunnisa Mohd Hamdi(G4-DR ELEXSON)

# data[].attributes.subject
58682 -Khairunnisa Mohd Hamdi(G4-DR ELEXSON)

# data[].attributes.body
The function of ribosome is to make proteins for the cells. So if the ribosomes do not function well, they wouldn't be able to produce protein for other cells. It causes cells to stop working and alter the many process as proteins are required.
If the ribosomes are not working, then there would be no MRNA.
An enzyme will need proteins which will activate the enzyme and bind to them .Some enzymes are responsible to "turn on " and "turn off" cell activites.
If all of these reactions don't take place, it will alter every process that occurs in the cel.

# data[].attributes.body
If the chloroplast in the plant cells cannot function well , the photosynthesis process cannot occur and food cannot produce by the autotroph plants . Besides that , ATP and NADPH cannot produce because the grana and thylakoid membrane provide large surface area for chlorophyll to trap the light energy . Next , the chloroplast cannot function well will interupt the production of sugar molecules because the stroma in the chloroplast contains enzyme to carry out light-independent reaction (Calvin cycle ) and the production of high energy organic molecules

# data[].attributes.body
If the mitochondria of a a cell stop working, almost all of the metabolic reaction cannot occur efficiently such as the glycolysis process.. When mitochondria not functioning, the production of ATP are low... Thus, the cell have to undergo anaerobic respiration to produce pyruvate for glycolysis but in a small amount.. And less efficient

# data[].attributes.body
If vacuole in plant cells does not function well, the plant will lose its turgidity due to the lack of water storage. A cell in which the vacuole contains all the water it needs is said to be in a turgid state. A state of wilt shows a shortage of water and a cell is said to have lost its turgor. Next, if vacuole does not function well, plant cells will have trouble of growing. This is because the high hydrostatic pressure produced by vacuoles assists in cell elongation but only when the cell wall is made soft enough for extension to take place. Not only that, if vacuole fails to function, the acidity will be disoriented. This can be proven as the vacuolar membrane acts as a proton pump. It uses energy from adenosine triphosphate (ATP) to pump H+ ions into the contents of the vacuole. This maintains acid conditions inside it.

# data[].attributes.body
Dear Students, this padlet functions as a platform for discussion on the above topic. Please use it wisely as marks will be given based on the critical feedback and rationale of your discussion. Please do indicate your group origin and matrix number before you post to ease evaluation by us. Cheers!