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35. yellow marrow- A storage area for fat cells

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35. yellow marrow- A storage area for fat cells

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Yellow bone marrow is located in the cavities of long bones. Learn more about its anatomy on Kenhub!

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34. vertebrae- 26 bones in the spinal column 

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34. vertebrae- 26 bones in the spinal column 

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33. ulna- large bone of lower arm with a projection called the olecranon process at its upper end, forming the elbow 

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33. ulna- large bone of lower arm with a projection called the olecranon process at its upper end, forming the elbow 

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32. tibia- the larger weight-bearing bone of the lower leg commonly called the shin bone

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32. tibia- the larger weight-bearing bone of the lower leg commonly called the shin bone

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The (plural tibiae or tibias), also known as the shinbone or shankbone, is the larger, stronger, and anterior (frontal) of the two bones in the leg below the knee in vertebrates (the other being the fibula, behind and to the outside of the tibia), and it connects the knee with the ankle bones. The tibia is found on the medial side of the leg next to the fibula and closer to the median plane or centre-line. The tibia is connected to the fibula by the interosseous membrane of the leg, forming a type of fibrous joint called a syndesmosis with very little movement. The tibia is named for the flute . It is the second largest bone in the human body next to the femur. The leg bones are the strongest long bones as they support the rest of the body.

In human anatomy, the tibia is the second largest bone next to the femur. As in other vertebrates the tibia is one of two bones in the lower leg, the other being the fibula, and is a component of the knee and ankle joints.

The ossification or formation of the bone starts from three centers; one in the shaft and one in each extremity.

The tibia is categorized as a long bone and is as such composed of a diaphysis and two epiphyses. The diaphysis is the midsection of the tibia, also known as the shaft or body. While the epiphyses are the two rounded extremities of the bone; an upper (also known as superior or proximal) closest to the thigh and a lower (also known as inferior or distal) closest to the foot. The tibia is most contracted in the lower third and the distal extremity is smaller than the proximal.

The proximal or upper extremity of the tibia is expanded in the transverse plane with a medial and lateral condyle, which are both flattened in the horizontal plane. The medial condyle is the larger of the two and is better supported over the shaft. The upper surfaces of the condyles articulate with the femur to form the tibiofemoral joint, the weightbearing part of the kneejoint.

The medial and lateral condyle are separated by the intercondylar area, where the cruciate ligaments and the menisci attach. Here the medial and lateral intercondylar tubercle forms the intercondylar eminence. Together with the medial and lateral condyle the intercondylar region forms the tibial plateau, which both articulates with and is anchored to the lower extremity of the femur. The intercondylar eminence divides the intercondylar area into an anterior and posterior part. The anterolateral region of the anterior intercondylar area are perforated by numerous small openings for nutrient arteries. The articular surfaces of both condyles are concave, particularly centrally. The flatter outer margins are in contact with the menisci. The medial condyles superior surface is oval in form and extends laterally onto the side of medial intercondylar tubercle. The lateral condyles superior surface is more circular in form and its medial edge extends onto the side of the lateral intercondylar tubercle. The posterior surface of the medial condyle bears a horizontal groove for part of the attachment of the semimembranosus muscle, whereas the lateral condyle has a circular facet for articulation with the head of the fibula. Beneath the condyles is the tibial tuberosity which serves for attachment of the patellar ligament, a continuation of the quadriceps femoris muscle.

The superior articular surface presents two smooth articular facets.

The medial facet, oval in shape, is slightly concave from side to side, and from before backward.

The lateral, nearly circular, is concave from side to side, but slightly convex from before backward, especially at its posterior part, where it is prolonged on to the posterior surface for a short distance.

The central portions of these facets articulate with the condyles of the femur, while their peripheral portions support the menisci of the knee joint, which here intervene between the two bones.

Between the articular facets in the intercondylar area, but nearer the posterior than the anterior aspect of the bone, is the intercondyloid eminence ( spine of tibia), surmounted on either side by a prominent tubercle, on to the sides of which the articular facets are prolonged; in front of and behind the intercondyloid eminence are rough depressions for the attachment of the anterior and posterior cruciate ligaments and the menisci.

The anterior surfaces of the condyles are continuous with one another, forming a large somewhat flattened area; this area is triangular, broad above, and perforated by large vascular foramina; narrow below where it ends in a large oblong elevation, the tuberosity of the tibia, which gives attachment to the patellar ligament; a bursa intervenes between the deep surface of the ligament and the part of the bone immediately above the tuberosity.

Posteriorly, the condyles are separated from each other by a shallow depression, the posterior intercondyloid fossa, which gives attachment to part of the posterior cruciate ligament of the knee-joint. The medial condyle presents posteriorly a deep transverse groove, for the insertion of the tendon of the semimembranosus.

Its medial surface is convex, rough, and prominent; it gives attachment to the medial collateral ligament.

The lateral condyle presents posteriorly a flat articular facet, nearly circular in form, directed downward, backward, and lateralward, for articulation with the head of the fibula. Its lateral surface is convex, rough, and prominent in front: on it is an eminence, situated on a level with the upper border of the tuberosity and at the junction of its anterior and lateral surfaces, for the attachment of the iliotibial band. Just below this a part of the extensor digitorum longus takes origin and a slip from the tendon of the biceps femoris is inserted.

The shaft or body of the tibia is triangular in cross-section and forms three borders: An anterior, medial and lateral or interosseous border. These three borders form three surfaces; the medial, lateral and posterior. The forward flat part of the tibia is called the fibia, often confused with the fibula.

The anterior crest or border, the most prominent of the three, commences above at the tuberosity, and ends below at the anterior margin of the medial malleolus. It is sinuous and prominent in the upper two-thirds of its extent, but smooth and rounded below; it gives attachment to the deep fascia of the leg.

The medial border is smooth and rounded above and below, but more prominent in the center; it begins at the back part of the medial condyle, and ends at the posterior border of the medial malleolus; its upper part gives attachment to the tibial collateral ligament of the knee-joint to the extent of about 5 cm., and insertion to some fibers of the popliteus muscle; from its middle third some fibers of the soleus and flexor digitorum longus muscles take origin.

The interosseous crest or lateral border is thin and prominent, especially its central part, and gives attachment to the interosseous membrane; it commences above in front of the fibular articular facet, and bifurcates below, to form the boundaries of a triangular rough surface, for the attachment of the interosseous ligament connecting the tibia and fibula.

The medial surface is smooth, convex, and broader above than below; its upper third, directed forward and medialward, is covered by the aponeurosis derived from the tendon of the sartorius, and by the tendons of the Gracilis and Semitendinosus, all of which are inserted nearly as far forward as the anterior crest; in the rest of its extent it is subcutaneous.

The lateral surface is narrower than the medial; its upper two-thirds present a shallow groove for the origin of the Tibialis anterior; its lower third is smooth, convex, curves gradually forward to the anterior aspect of the bone, and is covered by the tendons of the Tibialis anterior, Extensor hallucis longus, and Extensor digitorum longus, arranged in this order from the medial side.

The posterior surface presents, at its upper part, a prominent ridge, the popliteal line, which extends obliquely downward from the back part of the articular facet for the fibula to the medial border, at the junction of its upper and middle thirds; it marks the lower limit of the insertion of the Popliteus, serves for the attachment of the fascia covering this muscle, and gives origin to part of the Soleus, Flexor digitorum longus, and Tibialis posterior. The triangular area, above this line, gives insertion to the Popliteus. The middle third of the posterior surface is divided by a vertical ridge into two parts; the ridge begins at the popliteal line and is well-marked above, but indistinct below; the medial and broader portion gives origin to the Flexor digitorum longus, the lateral and narrower to part of the Tibialis posterior. The remaining part of the posterior surface is smooth and covered by the Tibialis posterior, Flexor digitorum longus, and Flexor hallucis longus. Immediately below the popliteal line is the nutrient foramen, which is large and directed obliquely downward.

The distal end of the tibia is much smaller than the proximal end and presents five surfaces; it is prolonged downward on its medial side as a strong pyramidal process, the medial malleolus. The lower extremity of the tibia together with the fibula and talus forms the ankle joint.

The inferior articular surface is quadrilateral, and smooth for articulation with the talus. It is concave from before backward, broader in front than behind, and traversed from before backward by a slight elevation, separating two depressions. It is continuous with that on the medial malleolus.

The anterior surface of the lower extremity is smooth and rounded above, and covered by the tendons of the Extensor muscles; its lower margin presents a rough transverse depression for the attachment of the articular capsule of the ankle-joint.

The posterior surface is traversed by a shallow groove directed obliquely downward and medialward, continuous with a similar groove on the posterior surface of the talus and serving for the passage of the tendon of the Flexor hallucis longus.

The lateral surface presents a triangular rough depression for the attachment of the inferior interosseous ligament connecting it with the fibula; the lower part of this depression is smooth, covered with cartilage in the fresh state, and articulates with the fibula. The surface is bounded by two prominent borders (the anterior and posterior colliculi), continuous above with the interosseous crest; they afford attachment to the anterior and posterior ligaments of the lateral malleolus.

The medial surface -- see medial malleolus for details.

Ankle fractures of the tibia have several classification systems based on location or mechanism:

The tibia is supplied with blood from two sources: A nutrient artery, as the main source, and periosteal vessels derived from the anterior tibial artery.

The tibia is a part of four joints; the knee, ankle, superior and inferior tibiofibular joint.

In the knee the tibia forms one of the two articulations with the femur, often referred to as the tibiofemoral components of the knee joint. This is the weightbearing part of the knee joint. The tibiofibular joints are the articulations between the tibia and fibula which allows very little movement.[citation needed ] The proximal tibiofibular joint is a small plane joint. The joint is formed between the undersurface of the lateral tibial condyle and the head of fibula. The joint capsule is reinforced by anterior and posterior ligament of the head of the fibula. The distal tibiofibular joint (tibiofibular syndesmosis) is formed by the rough, convex surface of the medial side of the distal end of the fibula, and a rough concave surface on the lateral side of the tibia.

The part of the ankle joint known as the talocrural joint, is a synovial hinge joint that connects the distal ends of the tibia and fibula in the lower limb with the proximal end of the talus. The articulation between the tibia and the talus bears more weight than between the smaller fibula and the talus.[citation needed ]

The tibia is ossified from three centers; a primary center for the diaphysis (shaft) and a secondary center for each epiphysis (extremity). Ossification begins in the center of the body, about the seventh week of fetal life, and gradually extends toward the extremities.

The center for the upper epiphysis appears before or shortly after birth at close to 34 weeks gestation; it is flattened in form, and has a thin tongue-shaped process in front, which forms the tuberosity; that for the lower epiphysis appears in the second year.

The lower epiphysis fuses with the tibial shaft at about the eighteenth, and the upper one fuses about the twentieth year.

Two additional centers occasionally exist, one for the tongue-shaped process of the upper epiphysis, which forms the tuberosity, and one for the medial malleolus.

The tibia has been modeled as taking an axial force during walking that is up to 4.7 bodyweight. Its bending moment in the sagittal plane in the late stance phase is up to 71.6 bodyweight times millimetre.

Fractures of the tibia can be divided into those that only involve the tibia; bumper fracture, Segond fracture, Gosselin fracture, toddler's fracture, and those including both the tibia and fibula; trimalleolar fracture, bimalleolar fracture, Pott's fracture.

In Judaism, the tibia, or shankbone, of a goat is used in the Passover Seder plate.

The structure of the tibia in most other tetrapods is essentially similar to that in humans. The tuberosity of the tibia, a crest to which the patellar ligament attaches in mammals, is instead the point for the tendon of the quadriceps muscle in reptiles, birds, and amphibians, which have no patella.

This article incorporates text in the public domain from page 256 of the 20th edition of Gray's Anatomy (1918)

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The (plural tibiae or tibias), also known as the shinbone or shankbone, is the larger, stronger, and anterior (frontal) of the two bones in the leg below the knee in vertebrates (the other being the fibula, behind and to the outside of the tibia), and it connects the knee with the ankle bones.

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In the human body, the tarsus ( pl.: tarsi) is a cluster of seven articulating bones in each foot situated between the lower end of the tibia and the fibula of the lower leg and the metatarsus. It is made up of the midfoot ( cuboid, medial, intermediate, and lateral cuneiform, and navicular) and hindfoot ( talus and calcaneus).

The tarsus articulates with the bones of the metatarsus, which in turn articulate with the proximal phalanges of the toes. The joint between the tibia and fibula above and the tarsus below is referred to as the ankle joint proper.

In humans the largest bone in the tarsus is the calcaneus, which is the weight-bearing bone within the heel of the foot.

Location of accessory tarsal bones

The talus bone or ankle bone is connected superiorly to the two bones of the lower leg, the tibia and fibula, to form the ankle joint or talocrural joint; inferiorly, at the subtalar joint, to the calcaneus or heel bone. Together, the talus and calcaneus form the hindfoot.

The five irregular bones of the midfoot-the cuboid, navicular, and three cuneiform bones-form the arches of the foot which serves as a shock absorber. The midfoot is connected to the hind- and forefoot by muscles and the plantar fascia.

The complex motion of the subtalar joint occurs in three planes and produces subtalar inversion and eversion. Along with the transverse tarsal joint (i.e. talonavicular and calcaneocuboid joint), the subtalar joint transforms tibial rotation into forefoot supination and pronation. The axis of rotation in the joint is directed upward 42 degrees from the horizontal plane and 16 degrees medially from the midline of the foot. However, together, the subtalar facets form a screw or Archimedean spiral (right-handed in the right foot) about which subtalar motion occurs. So, during subtalar inversion, the calcaneus also rotates clockwise and translates forward along the axis of the screw. Average subtalar motion is 20-30 degrees inversion and 5-10 degrees eversion. Functional motion during the gait cycle is 10-15 degrees (the heel strikes the ground in slight inversion followed by quick eversion).

The talonavicular and calcaneocuboid joints (i.e. between the talus and navicular bones, and the calcaneus and cuboid bones) form the so-called transverse tarsal joint or Chopart's joint. It has two axes of motion. Inversion and eversion occur about a longitudinal axis oriented 15 degrees upward from the horizontal plane and 9 degrees medially from the longitudinal axis of the foot. Flexion and extension occur primarily about an oblique axis oriented 52 degrees upward from the horizontal plane and 57 degrees anteromedially (forward-inward). talonavicular motion is 7 degrees flexion-extension and 17 degrees pronation-supination; while calcaneocuboid motion is 2 degrees flexion-extension and 7 degrees pronation-supination.

The motions of the subtalar and transverse talar joints interact to make the foot either flexible or rigid. With the subtalar joint in eversion, the two joints of the transverse joint are parallel, which make movements in this joint possible. With the subtalar joint in inversion, the axes of the transverse joint are convergent, movements in this joint are thus locked and the midfoot rigid.

In primitive tetrapods, such as , the tarsus consists of three rows of bones. There are three proximal tarsals, the tibiale, intermedium, and fibulare, named for their points of articulation with the bones of the lower limb. These are followed by a second row of four bones, referred to as the centralia (singular: centrale), and then a row of five distal tarsals, each articulating with a single metatarsal. In the great majority of tetrapods, including all of those alive today, this simple pattern is modified by the loss and fusion of some of the bones.

In reptiles and mammals, there are normally just two proximal tarsals, the calcaneus (equivalent to the amphibian fibulare) and the talus (probably derived from a fusion of multiple bones). In mammals, including humans, the talus forms a hinge joint with the tibia, a feature especially well developed in the artiodactyls. The calcaneus is also modified, forming a heel for the attachment of the Achilles tendon. Neither of these adaptations is found in reptiles, which have a relatively simple structure to both bones.

The fifth distal tarsal disappears relatively early in evolution, with the remainder becoming the cuneiform and cuboid bones. Reptiles usually retain two centralia, while mammals typically have only one (the navicular).

In birds, the tarsus has disappeared, with the proximal tarsals having fused with the tibia, the centralia having disappeared, and the distal bones having fused with the metatarsals to form a single tarsometatarsus bone, effectively giving the leg a third segment.

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In the human body, the tarsus ( pl.: tarsi) is a cluster of seven articulating bones in each foot situated between the lower end of the tibia and the fibula of the lower leg and the metatarsus. It is made up of the midfoot ( cuboid, medial, intermediate, and lateral cuneiform, and navicular) and hindfoot ( talus and calcaneus).

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30. sutures- areas where the cranial bones have joined together

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30. sutures- areas where the cranial bones have joined together

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Learning Objectives

List and identify the bones of the brain case and face

Locate the major suture lines of the skull and name the bones associated with each

Locate and define the boundaries of the anterior, middle, and posterior cranial fossae, the temporal fossa, and infratemporal fossa

Define the paranasal sinuses and identify the location of each

Name the bones that make up the walls of the orbit and identify the openings associated with the orbit

Identify the bones and structures that form the nasal septum and nasal conchae, and locate the hyoid bone

Identify the bony openings of the skull

The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault (Figure 1). The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws. The rounded brain case surrounds and protects the brain and houses the middle and inner ear structures.

In the adult, the skull consists of 22 individual bones, 21 of which are immobile and united into a single unit. The 22nd bone is the mandible (lower jaw), which is the only moveable bone of the skull.

Watch this video to view a rotating and exploded skull, with color-coded bones. Which bone (yellow) is centrally located and joins with most of the other bones of the skull?

Anterior View of Skull

The anterior skull consists of the facial bones and provides the bony support for the eyes and structures of the face. This view of the skull is dominated by the openings of the orbits and the nasal cavity. Also seen are the upper and lower jaws, with their respective teeth (Figure 2).

The orbit is the bony socket that houses the eyeball and muscles that move the eyeball or open the upper eyelid. The upper margin of the anterior orbit is the supraorbital margin. Located near the midpoint of the supraorbital margin is a small opening called the supraorbital foramen. This provides for passage of a sensory nerve to the skin of the forehead. Below the orbit is the infraorbital foramen, which is the point of emergence for a sensory nerve that supplies the anterior face below the orbit.

Inside the nasal area of the skull, the nasal cavity is divided into halves by the nasal septum. The upper portion of the nasal septum is formed by the perpendicular plate of the ethmoid bone and the lower portion is the vomer bone. Each side of the nasal cavity is triangular in shape, with a broad inferior space that narrows superiorly. When looking into the nasal cavity from the front of the skull, two bony plates are seen projecting from each lateral wall. The larger of these is the inferior nasal concha, an independent bone of the skull. Located just above the inferior concha is the middle nasal concha, which is part of the ethmoid bone. A third bony plate, also part of the ethmoid bone, is the superior nasal concha. It is much smaller and out of sight, above the middle concha. The superior nasal concha is located just lateral to the perpendicular plate, in the upper nasal cavity.

Lateral View of Skull

A view of the lateral skull is dominated by the large, rounded brain case above and the upper and lower jaws with their teeth below (Figure 3). Separating these areas is the bridge of bone called the zygomatic arch. The zygomatic arch is the bony arch on the side of skull that spans from the area of the cheek to just above the ear canal. It is formed by the junction of two bony processes: a short anterior component, the temporal process of the zygomatic bone (the cheekbone) and a longer posterior portion, the zygomatic process of the temporal bone, extending forward from the temporal bone. Thus the temporal process (anteriorly) and the zygomatic process (posteriorly) join together, like the two ends of a drawbridge, to form the zygomatic arch. One of the major muscles that pulls the mandible upward during biting and chewing arises from the zygomatic arch.

On the lateral side of the brain case, above the level of the zygomatic arch, is a shallow space called the temporal fossa. Below the level of the zygomatic arch and deep to the vertical portion of the mandible is another space called the infratemporal fossa. Both the temporal fossa and infratemporal fossa contain muscles that act on the mandible during chewing.

Bones of the Brain Case

The brain case contains and protects the brain. The interior space that is almost completely occupied by the brain is called the cranial cavity. This cavity is bounded superiorly by the rounded top of the skull, which is called the calvaria (skullcap), and the lateral and posterior sides of the skull. The bones that form the top and sides of the brain case are usually referred to as the "flat" bones of the skull.

The floor of the brain case is referred to as the base of the skull. This is a complex area that varies in depth and has numerous openings for the passage of cranial nerves, blood vessels, and the spinal cord. Inside the skull, the base is subdivided into three large spaces, called the anterior cranial fossa, middle cranial fossa, and posterior cranial fossa (fossa = "trench or ditch") (Figure 4). From anterior to posterior, the fossae increase in depth. The shape and depth of each fossa corresponds to the shape and size of the brain region that each houses. The boundaries and openings of the cranial fossae (singular = fossa) will be described in a later section.

The brain case consists of eight bones. These include the paired parietal and temporal bones, plus the unpaired frontal, occipital, sphenoid, and ethmoid bones.

Parietal Bone

The parietal bone forms most of the upper lateral side of the skull (see Figure 3). These are paired bones, with the right and left parietal bones joining together at the top of the skull. Each parietal bone is also bounded anteriorly by the frontal bone, inferiorly by the temporal bone, and posteriorly by the occipital bone.

Temporal Bone

The temporal bone forms the lower lateral side of the skull (see Figure 3). Common wisdom has it that the temporal bone (temporal = "time") is so named because this area of the head (the temple) is where hair typically first turns gray, indicating the passage of time.

The temporal bone is subdivided into several regions (Figure 5). The flattened, upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting inferiorly from this region is a large prominence, the mastoid process, which serves as a muscle attachment site. The mastoid process can easily be felt on the side of the head just behind your earlobe. On the interior of the skull, the petrous portion of each temporal bone forms the prominent, diagonally oriented petrous ridge in the floor of the cranial cavity. Located inside each petrous ridge are small cavities that house the structures of the middle and inner ears.

Important landmarks of the temporal bone, as shown in Figure 6, include the following:

External acoustic meatus (ear canal)-This is the large opening on the lateral side of the skull that is associated with the ear.

Internal acoustic meatus-This opening is located inside the cranial cavity, on the medial side of the petrous ridge. It connects to the middle and inner ear cavities of the temporal bone.

Mandibular fossa-This is the deep, oval-shaped depression located on the external base of the skull, just in front of the external acoustic meatus. The mandible (lower jaw) joins with the skull at this site as part of the temporomandibular joint, which allows for movements of the mandible during opening and closing of the mouth.

Articular tubercle-The smooth ridge located immediately anterior to the mandibular fossa. Both the articular tubercle and mandibular fossa contribute to the temporomandibular joint, the joint that provides for movements between the temporal bone of the skull and the mandible.

Styloid process-Posterior to the mandibular fossa on the external base of the skull is an elongated, downward bony projection called the styloid process, so named because of its resemblance to a stylus (a pen or writing tool). This structure serves as an attachment site for several small muscles and for a ligament that supports the hyoid bone of the neck. (See also Figure 5.)

Stylomastoid foramen-This small opening is located between the styloid process and mastoid process. This is the point of exit for the cranial nerve that supplies the facial muscles.

Carotid canal-The carotid canal is a zig-zag shaped tunnel that provides passage through the base of the skull for one of the major arteries that supplies the brain. Its entrance is located on the outside base of the skull, anteromedial to the styloid process. The canal then runs anteromedially within the bony base of the skull, and then turns upward to its exit in the floor of the middle cranial cavity, above the foramen lacerum.

Frontal Bone

The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella (see Figure 3). The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin, is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin, forming rounded brow ridges. These are located just behind your eyebrows and vary in size among individuals, although they are generally larger in males. Inside the cranial cavity, the frontal bone extends posteriorly. This flattened region forms both the roof of the orbit below and the floor of the anterior cranial cavity above (see Figure 6b).

Occipital Bone

The occipital bone is the single bone that forms the posterior skull and posterior base of the cranial cavity (Figure 7; see also Figure 6). On its outside surface, at the posterior midline, is a small protrusion called the external occipital protuberance, which serves as an attachment site for a ligament of the posterior neck. Lateral to either side of this bump is a superior nuchal line (nuchal = "nape" or "posterior neck"). The nuchal lines represent the most superior point at which muscles of the neck attach to the skull, with only the scalp covering the skull above these lines. On the base of the skull, the occipital bone contains the large opening of the foramen magnum, which allows for passage of the spinal cord as it exits the skull. On either side of the foramen magnum is an oval-shaped occipital condyle. These condyles form joints with the first cervical vertebra and thus support the skull on top of the vertebral column.

Sphenoid Bone

The sphenoid bone is a single, complex bone of the central skull (Figure 8). It serves as a "keystone" bone, because it joins with almost every other bone of the skull. The sphenoid forms much of the base of the central skull (see Figure 6) and also extends laterally to contribute to the sides of the skull (see Figure 3). Inside the cranial cavity, the right and left lesser wings of the sphenoid bone, which resemble the wings of a flying bird, form the lip of a prominent ridge that marks the boundary between the anterior and middle cranial fossae. The sella turcica ("Turkish saddle") is located at the midline of the middle cranial fossa. This bony region of the sphenoid bone is named for its resemblance to the horse saddles used by the Ottoman Turks, with a high back and a tall front. The rounded depression in the floor of the sella turcica is the hypophyseal (pituitary) fossa, which houses the pea-sized pituitary (hypophyseal) gland. The greater wings of the sphenoid bone extend laterally to either side away from the sella turcica, where they form the anterior floor of the middle cranial fossa. The greater wing is best seen on the outside of the lateral skull, where it forms a rectangular area immediately anterior to the squamous portion of the temporal bone.

On the inferior aspect of the skull, each half of the sphenoid bone forms two thin, vertically oriented bony plates. These are the medial pterygoid plate and lateral pterygoid plate (pterygoid = "wing-shaped"). The right and left medial pterygoid plates form the posterior, lateral walls of the nasal cavity. The somewhat larger lateral pterygoid plates serve as attachment sites for chewing muscles that fill the infratemporal space and act on the mandible.

Ethmoid Bone

The ethmoid bone is a single, midline bone that forms the roof and lateral walls of the upper nasal cavity, the upper portion of the nasal septum, and contributes to the medial wall of the orbit (Figure 9 and Figure 10). On the interior of the skull, the ethmoid also forms a portion of the floor of the anterior cranial cavity (see Figure 6b).

Within the nasal cavity, the perpendicular plate of the ethmoid bone forms the upper portion of the nasal septum. The ethmoid bone also forms the lateral walls of the upper nasal cavity. Extending from each lateral wall are the superior nasal concha and middle nasal concha, which are thin, curved projections that extend into the nasal cavity (Figure 11).

In the cranial cavity, the ethmoid bone forms a small area at the midline in the floor of the anterior cranial fossa. This region also forms the narrow roof of the underlying nasal cavity. This portion of the ethmoid bone consists of two parts, the crista galli and cribriform plates. The crista galli ("rooster's comb or crest") is a small upward bony projection located at the midline. It functions as an anterior attachment point for one of the covering layers of the brain. To either side of the crista galli is the cribriform plate (cribrum = "sieve"), a small, flattened area with numerous small openings termed olfactory foramina. Small nerve branches from the olfactory areas of the nasal cavity pass through these openings to enter the brain.

The lateral portions of the ethmoid bone are located between the orbit and upper nasal cavity, and thus form the lateral nasal cavity wall and a portion of the medial orbit wall. Located inside this portion of the ethmoid bone are several small, air-filled spaces that are part of the paranasal sinus system of the skull.

Sutures of the Skull

A suture is an immobile joint between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the bones of the brain case are not straight, but instead follow irregular, tightly twisting paths. These twisting lines serve to tightly interlock the adjacent bones, thus adding strength to the skull for brain protection.

The two suture lines seen on the top of the skull are the coronal and sagittal sutures. The coronal suture runs from side to side across the skull, within the coronal plane of section (see Figure 3). It joins the frontal bone to the right and left parietal bones. The sagittal suture extends posteriorly from the coronal suture, running along the midline at the top of the skull in the sagittal plane of section (see Figure 7). It unites the right and left parietal bones. On the posterior skull, the sagittal suture terminates by joining the lambdoid suture. The lambdoid suture extends downward and laterally to either side away from its junction with the sagittal suture. The lambdoid suture joins the occipital bone to the right and left parietal and temporal bones. This suture is named for its upside-down "V" shape, which resembles the capital letter version of the Greek letter lambda (Λ). The squamous suture is located on the lateral skull. It unites the squamous portion of the temporal bone with the parietal bone (see Figure 3). At the intersection of four bones is the pterion, a small, capital-H-shaped suture line region that unites the frontal bone, parietal bone, squamous portion of the temporal bone, and greater wing of the sphenoid bone. It is the weakest part of the skull. The pterion is located approximately two finger widths above the zygomatic arch and a thumb's width posterior to the upward portion of the zygomatic bone.

Disorders of the Skeletal System

Head and traumatic brain injuries are major causes of immediate death and disability, with bleeding and infections as possible additional complications. According to the Centers for Disease Control and Prevention (2010), approximately 30 percent of all injury-related deaths in the United States are caused by head injuries. The majority of head injuries involve falls. They are most common among young children (ages 0-4 years), adolescents (15-19 years), and the elderly (over 65 years). Additional causes vary, but prominent among these are automobile and motorcycle accidents.

Strong blows to the brain-case portion of the skull can produce fractures. These may result in bleeding inside the skull with subsequent injury to the brain. The most common is a linear skull fracture, in which fracture lines radiate from the point of impact. Other fracture types include a comminuted fracture, in which the bone is broken into several pieces at the point of impact, or a depressed fracture, in which the fractured bone is pushed inward. In a contrecoup (counterblow) fracture, the bone at the point of impact is not broken, but instead a fracture occurs on the opposite side of the skull. Fractures of the occipital bone at the base of the skull can occur in this manner, producing a basilar fracture that can damage the artery that passes through the carotid canal.

A blow to the lateral side of the head may fracture the bones of the pterion. The pterion is an important clinical landmark because located immediately deep to it on the inside of the skull is a major branch of an artery that supplies the skull and covering layers of the brain. A strong blow to this region can fracture the bones around the pterion. If the underlying artery is damaged, bleeding can cause the formation of a hematoma (collection of blood) between the brain and interior of the skull. As blood accumulates, it will put pressure on the brain. Symptoms associated with a hematoma may not be apparent immediately following the injury, but if untreated, blood accumulation will exert increasing pressure on the brain and can result in death within a few hours.

Facial Bones of the Skull

The facial bones of the skull form the upper and lower jaws, the nose, nasal cavity and nasal septum, and the orbit. The facial bones include 14 bones, with six paired bones and two unpaired bones. The paired bones are the maxilla, palatine, zygomatic, nasal, lacrimal, and inferior nasal conchae bones. The unpaired bones are the vomer and mandible bones. Although classified with the brain-case bones, the ethmoid bone also contributes to the nasal septum and the walls of the nasal cavity and orbit.

Maxillary Bone

The maxillary bone, often referred to simply as the maxilla (plural = maxillae), is one of a pair that together form the upper jaw, much of the hard palate, the medial floor of the orbit, and the lateral base of the nose (see Figure 2). The curved, inferior margin of the maxillary bone that forms the upper jaw and contains the upper teeth is the alveolar process of the maxilla (Figure 12). Each tooth is anchored into a deep socket called an alveolus. On the anterior maxilla, just below the orbit, is the infraorbital foramen. This is the point of exit for a sensory nerve that supplies the nose, upper lip, and anterior cheek. On the inferior skull, the palatine process from each maxillary bone can be seen joining together at the midline to form the anterior three-quarters of the hard palate (see Figure 6a). The hard palate is the bony plate that forms the roof of the mouth and floor of the nasal cavity, separating the oral and nasal cavities.

Palatine Bone

The palatine bone is one of a pair of irregularly shaped bones that contribute small areas to the lateral walls of the nasal cavity and the medial wall of each orbit. The largest region of each of the palatine bone is the horizontal plate. The plates from the right and left palatine bones join together at the midline to form the posterior quarter of the hard palate (see Figure 6a). Thus, the palatine bones are best seen in an inferior view of the skull and hard palate.

Homeostatic Imbalances: Cleft Lip and Cleft Palate

During embryonic development, the right and left maxilla bones come together at the midline to form the upper jaw. At the same time, the muscle and skin overlying these bones join together to form the upper lip. Inside the mouth, the palatine processes of the maxilla bones, along with the horizontal plates of the right and left palatine bones, join together to form the hard palate. If an error occurs in these developmental processes, a birth defect of cleft lip or cleft palate may result.

Cleft lip is a common development defect that affects approximately 1:1000 births, most of which are male. This defect involves a partial or complete failure of the right and left portions of the upper lip to fuse together, leaving a cleft (gap).

A more severe developmental defect is cleft palate, which affects the hard palate. The hard palate is the bony structure that separates the nasal cavity from the oral cavity. It is formed during embryonic development by the midline fusion of the horizontal plates from the right and left palatine bones and the palatine processes of the maxilla bones. Cleft palate affects approximately 1:2500 births and is more common in females. It results from a failure of the two halves of the hard palate to completely come together and fuse at the midline, thus leaving a gap between them. This gap allows for communication between the nasal and oral cavities. In severe cases, the bony gap continues into the anterior upper jaw where the alveolar processes of the maxilla bones also do not properly join together above the front teeth. If this occurs, a cleft lip will also be seen. Because of the communication between the oral and nasal cavities, a cleft palate makes it very difficult for an infant to generate the suckling needed for nursing, thus leaving the infant at risk for malnutrition. Surgical repair is required to correct cleft palate defects.

Zygomatic Bone

The zygomatic bone is also known as the cheekbone. Each of the paired zygomatic bones forms much of the lateral wall of the orbit and the lateral-inferior margins of the anterior orbital opening (see Figure 2). The short temporal process of the zygomatic bone projects posteriorly, where it forms the anterior portion of the zygomatic arch (see Figure 3).

Nasal Bone

The nasal bone is one of two small bones that articulate (join) with each other to form the bony base (bridge) of the nose. They also support the cartilages that form the lateral walls of the nose (see Figure 9). These are the bones that are damaged when the nose is broken.

Lacrimal Bone

Each lacrimal bone is a small, rectangular bone that forms the anterior, medial wall of the orbit (see Figure 2 and Figure 3). The anterior portion of the lacrimal bone forms a shallow depression called the lacrimal fossa, and extending inferiorly from this is the nasolacrimal canal. The lacrimal fluid (tears of the eye), which serves to maintain the moist surface of the eye, drains at the medial corner of the eye into the nasolacrimal canal. This duct then extends downward to open into the nasal cavity, behind the inferior nasal concha. In the nasal cavity, the lacrimal fluid normally drains posteriorly, but with an increased flow of tears due to crying or eye irritation, some fluid will also drain anteriorly, thus causing a runny nose.

Inferior Nasal Conchae

The right and left inferior nasal conchae form a curved bony plate that projects into the nasal cavity space from the lower lateral wall (see Figure 11). The inferior concha is the largest of the nasal conchae and can easily be seen when looking into the anterior opening of the nasal cavity.

Vomer Bone

The unpaired vomer bone, often referred to simply as the vomer, is triangular-shaped and forms the posterior-inferior part of the nasal septum (see Figure 9). The vomer is best seen when looking from behind into the posterior openings of the nasal cavity (see Figure 6a). In this view, the vomer is seen to form the entire height of the nasal septum. A much smaller portion of the vomer can also be seen when looking into the anterior opening of the nasal cavity.

Mandible

The mandible forms the lower jaw and is the only moveable bone of the skull. At the time of birth, the mandible consists of paired right and left bones, but these fuse together during the first year to form the single U-shaped mandible of the adult skull. Each side of the mandible consists of a horizontal body and posteriorly, a vertically oriented ramus of the mandible (ramus = "branch"). The outside margin of the mandible, where the body and ramus come together is called the angle of the mandible (Figure 13).

The ramus on each side of the mandible has two upward-going bony projections. The more anterior projection is the flattened coronoid process of the mandible, which provides attachment for one of the biting muscles. The posterior projection is the condylar process of the mandible, which is topped by the oval-shaped condyle. The condyle of the mandible articulates (joins) with the mandibular fossa and articular tubercle of the temporal bone. Together these articulations form the temporomandibular joint, which allows for opening and closing of the mouth (see Figure 3). The broad U-shaped curve located between the coronoid and condylar processes is the mandibular notch.

Important landmarks for the mandible include the following:

Alveolar process of the mandible-This is the upper border of the mandibular body and serves to anchor the lower teeth.

Mental protuberance-The forward projection from the inferior margin of the anterior mandible that forms the chin (mental = "chin").

Mental foramen-The opening located on each side of the anterior-lateral mandible, which is the exit site for a sensory nerve that supplies the chin.

Mylohyoid line-This bony ridge extends along the inner aspect of the mandibular body (see Figure 9). The muscle that forms the floor of the oral cavity attaches to the mylohyoid lines on both sides of the mandible.

Mandibular foramen-This opening is located on the medial side of the ramus of the mandible. The opening leads into a tunnel that runs down the length of the mandibular body. The sensory nerve and blood vessels that supply the lower teeth enter the mandibular foramen and then follow this tunnel. Thus, to numb the lower teeth prior to dental work, the dentist must inject anesthesia into the lateral wall of the oral cavity at a point prior to where this sensory nerve enters the mandibular foramen.

Lingula-This small flap of bone is named for its shape (lingula = "little tongue"). It is located immediately next to the mandibular foramen, on the medial side of the ramus. A ligament that anchors the mandible during opening and closing of the mouth extends down from the base of the skull and attaches to the lingula.

The Orbit

The orbit is the bony socket that houses the eyeball and contains the muscles that move the eyeball or open the upper eyelid. Each orbit is cone-shaped, with a narrow posterior region that widens toward the large anterior opening. To help protect the eye, the bony margins of the anterior opening are thickened and somewhat constricted. The medial walls of the two orbits are parallel to each other but each lateral wall diverges away from the midline at a 45° angle. This divergence provides greater lateral peripheral vision.

The walls of each orbit include contributions from seven skull bones (Figure 14). The frontal bone forms the roof and the zygomatic bone forms the lateral wall and lateral floor. The medial floor is primarily formed by the maxilla, with a small contribution from the palatine bone. The ethmoid bone and lacrimal bone make up much of the medial wall and the sphenoid bone forms the posterior orbit.

At the posterior apex of the orbit is the opening of the optic canal, which allows for passage of the optic nerve from the retina to the brain. Lateral to this is the elongated and irregularly shaped superior orbital fissure, which provides passage for the artery that supplies the eyeball, sensory nerves, and the nerves that supply the muscles involved in eye movements.

The Nasal Septum and Nasal Conchae

The nasal septum consists of both bone and cartilage components (Figure 15; see also Figure 9). The upper portion of the septum is formed by the perpendicular plate of the ethmoid bone. The lower and posterior parts of the septum are formed by the triangular-shaped vomer bone. In an anterior view of the skull, the perpendicular plate of the ethmoid bone is easily seen inside the nasal opening as the upper nasal septum, but only a small portion of the vomer is seen as the inferior septum. A better view of the vomer bone is seen when looking into the posterior nasal cavity with an inferior view of the skull, where the vomer forms the full height of the nasal septum. The anterior nasal septum is formed by the septal cartilage, a flexible plate that fills in the gap between the perpendicular plate of the ethmoid and vomer bones. This cartilage also extends outward into the nose where it separates the right and left nostrils. The septal cartilage is not found in the dry skull.

Attached to the lateral wall on each side of the nasal cavity are the superior, middle, and inferior nasal conchae (singular = concha), which are named for their positions (see Figure 11). These are bony plates that curve downward as they project into the space of the nasal cavity. They serve to swirl the incoming air, which helps to warm and moisturize it before the air moves into the delicate air sacs of the lungs. This also allows mucus, secreted by the tissue lining the nasal cavity, to trap incoming dust, pollen, bacteria, and viruses. The largest of the conchae is the inferior nasal concha, which is an independent bone of the skull. The middle concha and the superior conchae, which is the smallest, are both formed by the ethmoid bone. When looking into the anterior nasal opening of the skull, only the inferior and middle conchae can be seen. The small superior nasal concha is well hidden above and behind the middle concha.

Cranial Fossae

Inside the skull, the floor of the cranial cavity is subdivided into three cranial fossae (spaces), which increase in depth from anterior to posterior (see Figure 4, Figure 6b, and Figure 9). Since the brain occupies these areas, the shape of each conforms to the shape of the brain regions that it contains. Each cranial fossa has anterior and posterior boundaries and is divided at the midline into right and left areas by a significant bony structure or opening.

Anterior Cranial Fossa

The anterior cranial fossa is the most anterior and the shallowest of the three cranial fossae. It overlies the orbits and contains the frontal lobes of the brain. Anteriorly, the anterior fossa is bounded by the frontal bone, which also forms the majority of the floor for this space. The lesser wings of the sphenoid bone form the prominent ledge that marks the boundary between the anterior and middle cranial fossae. Located in the floor of the anterior cranial fossa at the midline is a portion of the ethmoid bone, consisting of the upward projecting crista galli and to either side of this, the cribriform plates.

Middle Cranial Fossa

The middle cranial fossa is deeper and situated posterior to the anterior fossa. It extends from the lesser wings of the sphenoid bone anteriorly, to the petrous ridges (petrous portion of the temporal bones) posteriorly. The large, diagonally positioned petrous ridges give the middle cranial fossa a butterfly shape, making it narrow at the midline and broad laterally. The temporal lobes of the brain occupy this fossa. The middle cranial fossa is divided at the midline by the upward bony prominence of the sella turcica, a part of the sphenoid bone. The middle cranial fossa has several openings for the passage of blood vessels and cranial nerves (see Figure 6).

Openings in the middle cranial fossa are as follows:

Optic canal-This opening is located at the anterior lateral corner of the sella turcica. It provides for passage of the optic nerve into the orbit.

Superior orbital fissure-This large, irregular opening into the posterior orbit is located on the anterior wall of the middle cranial fossa, lateral to the optic canal and under the projecting margin of the lesser wing of the sphenoid bone. Nerves to the eyeball and associated muscles, and sensory nerves to the forehead pass through this opening.

Foramen rotundum-This rounded opening (rotundum = "round") is located in the floor of the middle cranial fossa, just inferior to the superior orbital fissure. It is the exit point for a major sensory nerve that supplies the cheek, nose, and upper teeth.

Foramen ovale of the middle cranial fossa-This large, oval-shaped opening in the floor of the middle cranial fossa provides passage for a major sensory nerve to the lateral head, cheek, chin, and lower teeth.

Foramen spinosum-This small opening, located posterior-lateral to the foramen ovale, is the entry point for an important artery that supplies the covering layers surrounding the brain. The branching pattern of this artery forms readily visible grooves on the internal surface of the skull and these grooves can be traced back to their origin at the foramen spinosum.

Carotid canal-This is the zig-zag passageway through which a major artery to the brain enters the skull. The entrance to the carotid canal is located on the inferior aspect of the skull, anteromedial to the styloid process (see Figure 6a). From here, the canal runs anteromedially within the bony base of the skull. Just above the foramen lacerum, the carotid canal opens into the middle cranial cavity, near the posterior-lateral base of the sella turcica.

Foramen lacerum-This irregular opening is located in the base of the skull, immediately inferior to the exit of the carotid canal. This opening is an artifact of the dry skull, because in life it is completely filled with cartilage. All the openings of the skull that provide for passage of nerves or blood vessels have smooth margins; the word lacerum ("ragged" or "torn") tells us that this opening has ragged edges and thus nothing passes through it.

Posterior Cranial Fossa

The posterior cranial fossa is the most posterior and deepest portion of the cranial cavity. It contains the cerebellum of the brain. The posterior fossa is bounded anteriorly by the petrous ridges, while the occipital bone forms the floor and posterior wall. It is divided at the midline by the large foramen magnum ("great aperture"), the opening that provides for passage of the spinal cord.

Located on the medial wall of the petrous ridge in the posterior cranial fossa is the internal acoustic meatus (see Figure 9). This opening provides for passage of the nerve from the hearing and equilibrium organs of the inner ear, and the nerve that supplies the muscles of the face. Located at the anterior-lateral margin of the foramen magnum is the hypoglossal canal. These emerge on the inferior aspect of the skull at the base of the occipital condyle and provide passage for an important nerve to the tongue.

Immediately inferior to the internal acoustic meatus is the large, irregularly shaped jugular foramen (see Figure 6a). Several cranial nerves from the brain exit the skull via this opening. It is also the exit point through the base of the skull for all the venous return blood leaving the brain. The venous structures that carry blood inside the skull form large, curved grooves on the inner walls of the posterior cranial fossa, which terminate at each jugular foramen.

Paranasal Sinuses

The paranasal sinuses are hollow, air-filled spaces located within certain bones of the skull (Figure 16). All of the sinuses communicate with the nasal cavity (paranasal = "next to nasal cavity") and are lined with nasal mucosa. They serve to reduce bone mass and thus lighten the skull, and they also add resonance to the voice. This second feature is most obvious when you have a cold or sinus congestion. These produce swelling of the mucosa and excess mucus production, which can obstruct the narrow passageways between the sinuses and the nasal cavity, causing your voice to sound different to yourself and others. This blockage can also allow the sinuses to fill with fluid, with the resulting pressure producing pain and discomfort.

The paranasal sinuses are named for the skull bone that each occupies. The frontal sinus is located just above the eyebrows, within the frontal bone (see Figure 15). This irregular space may be divided at the midline into bilateral spaces, or these may be fused into a single sinus space. The frontal sinus is the most anterior of the paranasal sinuses. The largest sinus is the maxillary sinus. These are paired and located within the right and left maxillary bones, where they occupy the area just below the orbits. The maxillary sinuses are most commonly involved during sinus infections. Because their connection to the nasal cavity is located high on their medial wall, they are difficult to drain. The sphenoid sinus is a single, midline sinus. It is located within the body of the sphenoid bone, just anterior and inferior to the sella turcica, thus making it the most posterior of the paranasal sinuses. The lateral aspects of the ethmoid bone contain multiple small spaces separated by very thin bony walls. Each of these spaces is called an ethmoid air cell. These are located on both sides of the ethmoid bone, between the upper nasal cavity and medial orbit, just behind the superior nasal conchae.

Hyoid Bone

The hyoid bone is an independent bone that does not contact any other bone and thus is not part of the skull (Figure 17). It is a small U-shaped bone located in the upper neck near the level of the inferior mandible, with the tips of the "U" pointing posteriorly. The hyoid serves as the base for the tongue above, and is attached to the larynx below and the pharynx posteriorly. The hyoid is held in position by a series of small muscles that attach to it either from above or below. These muscles act to move the hyoid up/down or forward/back. Movements of the hyoid are coordinated with movements of the tongue, larynx, and pharynx during swallowing and speaking.

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List and identify the bones of the brain case and face Locate the major suture lines of the skull and name the bones associated with each Locate and define the boundaries of the anterior, middle, and posterior cranial fossae, the temporal fossa, and infratemporal fossa Define the paranasal sinuses and

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29. sternum- “breastbone” the last bone of the axial skeleton 

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29. sternum- “breastbone” the last bone of the axial skeleton 

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The sternum or breastbone is a long flat bone located in the center of the chest. It connects to the ribs via cartilage and forms the front of the rib cage, thus helping to protect the heart, lungs, and major blood vessels from injury.

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28. skeletal system- Made up of organs called bones, An adult human has 206 bones

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28. skeletal system- Made up of organs called bones, An adult human has 206 bones

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The bony skeleton is divided into 2 parts: the axial skeleton and the appendicular skeleton. The axial skeleton is the central core unit, consisting of the skull, vertebrae, ribs, and sternum. The appendicular skeleton comprises the bones of the extremities. The human skeleton consists of 213 bones, of which 126 are part of the appendicular skeleton, 74 are part of the axial skeleton, and 6 are part of the auditory ossicles.

Bone is a solid organ that appears pinkish white externally and deep red internally when in a fresh state.Essentially, bone is of 2 types, compact (or cortical) bone and cancellous (or woven) bone. The relative quantities of compact and cancellous bone vary in different locations, depending on the relative requirements for strength and flexibility, respectively, at a given site.

As the name suggests, compact (cortical) bone is well-packed and densely organized bone. It appears ivorylike and is very strong. This type of bone is mainly found in the diaphyses of long bones. Cancellous (woven) bone, on the other hand, has loosely woven lattices with relatively less dense organization of the bone tissue. Cancellous bone is found in the epiphyses and metaphyses of long bones, among other locations.

Anatomically and structurally, the different types of bone are traditionally grouped as follows:

Long bones - Clavicle, humerus, radius, ulna, metacarpals, femur, tibia and fibula, metatarsals, and phalanges; the metacarpals, metatarsals, and phalanges are sometimes referred to as short long bones

Flat bones - Skull, mandible, scapula, sternum, and ribs

Short bones - Carpal and tarsal bones, patella, and sesamoids Irregular bones - Vertebrae, sacrum, coccyx, and hyoid bone

The long bone itself has different parts, as follows:

Diaphysis - This is the central and cortical shaft of a long bone; the narrowest part of the diaphysis is often referred to as the isthmus of the long bone.

Metaphysis - The diaphysis flares on either side to form the metaphysis, which is essentially cancellous bone

Epiphysis - This lies on either end of the long bone; in the adult, it is the remnant of the growing end of the long bone, whereas in a child, the ends of the long bone possess the growth plate and the epiphyses

Medullary cavity - This is the cavity within the long bone; it contains bone marrow and its constituents

Bone is covered by a membrane called the periosteum. The inner medullary cavity is lined with a membrane called the endosteum.

The periosteum, as described by Gray, has multiple small vessels tethering it to bone; these vessels provide a major part of its blood supply. The periosteum is attached to bone by fine fibers called Sharpey fibers. It constitutes a fibrous connective tissue sheath that surrounds the outer cortical surface of bone, except at joints, where bone is lined by articular cartilage. The periosteum contains blood vessels, nerve fibers, osteoblasts, and osteoclasts. It is thicker in children than in mature adults.

The periosteum is a vital structure in bone function, serving to nourish and protect the underlying cortical bone. This function is especially evident with subcutaneous bones like the tibia: when such bones are exposed and injured, their very survival may depend on the presence or absence of periosteum. Periosteum is essential for appositional growth and remodeling of bone. Because bone resorption typically exceeds bone formation as a person grows older, the medullary canal appears to widen with increasing age.

Images depicting the anatomy of the adult skeleton can be seen below.

Joints

The ends of bones articulate to form mobile (or, sometimes, nonmobile) units termed joints (see the images below). These are essentially the connections between the bony elements of the skeleton. In terms of the type of tissue that bridges them, joints may be described as synovial or fibrous, cartilaginous, or bony.

Synchondroses are cartilaginous joints (eg, the sternocostal joint). Synovial joints are lined by a specialized membrane called the synovial membrane and the articulating ends of the bones are lined by specialized cartilage termed hyaline cartilage. This makes the joint specially suited for mobility. Lubricating synovial fluid is secreted by the synovial membrane (columnar epithelium). This fluid also nourishes the articular cartilage, which has sparse blood supply. Repetitive joint movements in synovial joints allow the synovial fluid to replenish itself and maintain cartilage function. Examples of synovial joints include the knee, hip, elbow, and atlanto-axial joint.

The articular cartilage is itself not innervated.

The ends of long bones that articulate with each other are often flared to form bulbous projections called condyles. These are lined by articular or hyaline cartilage.

Vasculature

Bone derives its blood supply from nutrient arteries, which enter the medullary canal at fixed points in the cortex. A number of apertures may be found on the surface of the bone, many of them representing points where veins exit from the surface of the bone. These apertures are found more often at the metaphyseal ends of the long bones. In the flat bones of the skull, these venous channels are numerous and run within tortuous channels in the diploic tissue.

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skeletal system anatomy in adults overview

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The skeleton of the human being is a unique structure that has adapted to the needs of bipedal locomotion and erect posture. The structural peculiarities of the human skeleton give human beings their characteristic appearance and facial geometry.

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27. sinuses- Air spaces in the bones of the skull that act as resonating chambers for the voice

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27. sinuses- Air spaces in the bones of the skull that act as resonating chambers for the voice

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Sinusitis is an inflammation of your sinuses. It can cause facial pain and a stuffy or runny nose with thick mucus.

What is sinusitis (sinus infection)?

Sinusitis is an inflammation, or swelling, of the tissue lining your sinuses. Sinuses are structures inside your face that are normally filled with air. Bacterial infections, viral infections and allergies can irritate them, causing them to get blocked and filled with fluid. This can cause pressure and pain in your face, nasal congestion (a stuffy nose) and other symptoms.

Sinusitis is also sometimes called rhinosinusitis.

What are sinuses?

Your sinuses are four paired cavities (spaces) in your head. Narrow passages connect them. Sinuses make mucus that drains out of the passages in your nose. This drainage helps keep your nose clean and free of bacteria, allergens and other germs (pathogens).

Types of sinusitis

We describe types of sinusitis based on how long it's been going on (acute, subacute, chronic or recurrent) and what's causing it (bacteria, virus or fungus).

Acute, subacute, chronic and recurrent sinusitis

Acute sinusitis symptoms (nasal congestion, drainage, facial pain/pressure and decreased sense of smell) last less than four weeks. It's usually caused by viruses like the common cold.

Subacute sinusitis symptoms last four to 12 weeks.

Chronic sinusitis symptoms last at least 12 weeks. Bacteria are usually the cause.

Recurrent acute sinusitis symptoms come back four or more times in one year and last less than two weeks each time.

Bacterial and viral sinusitis

Viruses, like the ones that cause the common cold, cause most cases of sinusitis. Bacteria can cause sinusitis, or they can infect you after a case of viral sinusitis. If you have a runny nose, stuffy nose and facial pain that don't go away after ten days, you might have bacterial sinusitis. Your symptoms may seem to improve but then return and are worse than the initial symptoms. Antibiotics and decongestants usually work well on bacterial sinusitis.

Fungal sinusitis

Sinus infections caused by fungus are usually more serious than other forms of sinusitis. They're more likely to happen if you have a weakened immune system.

How do I know if I have sinusitis, COVID, a cold or an allergy?

Colds, COVID-19, allergies and sinus infections all have similar symptoms. It can be difficult to tell them apart. The common cold typically builds, peaks and slowly disappears. It lasts a few days to a week. Nasal allergies cause sneezing, itchy nose and eyes, congestion, runny nose and postnasal drip (mucus in your throat). They usually don't cause the facial pain that sinus infections do. COVID-19 can cause additional symptoms, like fever and shortness of breath.

A cold, COVID or allergies can all cause sinus infections. You can test yourself or have a provider test you for some viral infections, like COVID-19 and the flu.

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Sinus Infection: Common Causes & How To Treat It

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Sinusitis is an inflammation of the tissues in your sinuses. It's usually caused by viruses, but can also be caused by bacteria or allergies.

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The scapula ( pl.: scapulae or scapulas), also known as the shoulder blade, is the bone that connects the humerus (upper arm bone) with the clavicle (collar bone). Like their connected bones, the scapulae are paired, with each scapula on either side of the body being roughly a mirror image of the other. The name derives from the Classical Latin word for trowel or small shovel, which it was thought to resemble.

In compound terms, the prefix omo- is used for the shoulder blade in medical terminology. This prefix is derived from ὦμος (ōmos), the Ancient Greek word for shoulder, and is cognate with the Latin (h)umerus, which in Latin signifies either the shoulder or the upper arm bone.

The scapula forms the back of the shoulder girdle. In humans, it is a flat bone, roughly triangular in shape, placed on a posterolateral aspect of the thoracic cage.

The scapula is a thick, flat bone lying on the thoracic wall that provides an attachment for three groups of muscles: intrinsic, extrinsic, and stabilizing and rotating muscles. The intrinsic muscles of the scapula include the muscles of the rotator cuff-the subscapularis, teres minor, supraspinatus, and infraspinatus. These muscles attach to the surface of the scapula and are responsible for the internal and external rotation of the shoulder joint, along with humeral abduction.

The extrinsic muscles include the biceps, triceps, and deltoid muscles and attach to the coracoid process and supraglenoid tubercle of the scapula, infraglenoid tubercle of the scapula, and spine of the scapula. These muscles are responsible for several actions of the glenohumeral joint.

The third group, which is mainly responsible for stabilization and rotation of the scapula, consists of the trapezius, serratus anterior, levator scapulae, and rhomboid muscles. These attach to the medial, superior, and inferior borders of the scapula.

The head, processes, and the thickened parts of the bone contain cancellous tissue; the rest consists of a thin layer of compact tissue.

The central part of the supraspinatus fossa and the upper part of the infraspinatous fossa, but especially the former, are usually so thin in humans as to be semitransparent; occasionally the bone is found wanting in this situation, and the adjacent muscles are separated only by fibrous tissue. The scapula has two surfaces, three borders, three angles, and three processes.

3d model of scapula, along with annotations showing the various parts of the scapula

Front or subscapular fossa

The front of the scapula (also known as the costal or ventral surface) has a broad concavity called the subscapular fossa, to which the subscapularis muscle attaches. The medial two-thirds of the fossa have 3 longitudinal oblique ridges, and another thick ridge adjoins the lateral border; they run outward and upward. The ridges give attachment to the tendinous insertions, and the surfaces between them to the fleshy fibers, of the subscapularis muscle. The lateral third of the fossa is smooth and covered by the fibers of this muscle.

At the upper part of the fossa is a transverse depression, where the bone appears to be bent on itself along a line at right angles to and passing through the center of the glenoid cavity, forming a considerable angle, called the subscapular angle; this gives greater strength to the body of the bone by its arched form, while the summit of the arch serves to support the spine and acromion.

The costal surface superior of the scapula is the origin of 1st digitation for the serratus anterior origin.

The back of the scapula (also called the dorsal or posterior surface) is arched from above downward, and is subdivided into two unequal parts by the spine of the scapula. The portion above the spine is called the supraspinous fossa, and that below it the infraspinous fossa. The two fossae are connected by the spinoglenoid notch, situated lateral to the root of the spine.

The supraspinous fossa, above the spine of scapula, is concave, smooth, and broader at its vertebral than at its humeral end; its medial two-thirds give origin to the Supraspinatus. At its lateral surface resides the spinoglenoid fossa which is situated by the medial margin of the glenoid. The spinoglenoid fossa houses the suprascpular canal which forms a connecting passage between the suprascapular notch and the spinoglenoid notch conveying the suprascapular nerve and vessels.

The infraspinous fossa is much larger than the preceding; toward its vertebral margin a shallow concavity is seen at its upper part; its center presents a prominent convexity, while near the axillary border is a deep groove which runs from the upper toward the lower part. The medial two-thirds of the fossa give origin to the Infraspinatus; the lateral third is covered by this muscle.

There is a ridge on the outer part of the back of the scapula. This runs from the lower part of the glenoid cavity, downward and backward to the vertebral border, about 2.5 cm above the inferior angle. Attached to the ridge is a fibrous septum, which separates the infraspinatus muscle from the Teres major and Teres minor muscles. The upper two-thirds of the surface between the ridge and the axillary border is narrow, and is crossed near its center by a groove for the scapular circumflex vessels; the Teres minor attaches here.

The broad and narrow portions above alluded to are separated by an oblique line, which runs from the axillary border, downward and backward, to meet the elevated ridge: to it is attached a fibrous septum which separates the Teres muscles from each other.

Its lower third presents a broader, somewhat triangular surface, the inferior angle of the scapula, which gives origin to the Teres major, and over which the Latissimus dorsi glides; frequently the latter muscle takes origin by a few fibers from this part.

The acromion forms the summit of the shoulder, and is a large, somewhat triangular or oblong process, flattened from behind forward, projecting at first laterally, and then curving forward and upward, so as to overhang the glenoid cavity.

There are 3 angles:

The superior angle of the scapula or medial angle, is covered by the trapezius muscle. This angle is formed by the junction of the superior and medial borders of the scapula. The superior angle is located at the approximate level of the second thoracic vertebra. The superior angle of the scapula is thin, smooth, rounded, and inclined somewhat lateralward, and gives attachment to a few fibers of the levator scapulae muscle.

The inferior angle of the scapula is the lowest part of the scapula and is covered by the latissimus dorsi muscle. It moves forwards round the chest when the arm is abducted. The inferior angle is formed by the union of the medial and lateral borders of the scapula. It is thick and rough and its posterior or back surface affords attachment to the teres major and often to a few fibers of the latissimus dorsi. The anatomical plane that passes vertically through the inferior angle is named the scapular line.

The lateral angle of the scapula or glenoid angle also known as the head of the scapula is the thickest part of the scapula. It is broad and bears the glenoid fossa on its articular surface which is directed forward, laterally and slightly upwards, and articulates with the head of the humerus. The inferior angle is broader below than above and its vertical diameter is the longest. The surface is covered with cartilage in the fresh state; and its margins, slightly raised, give attachment to a fibrocartilaginous structure, the glenoidal labrum, which deepens the cavity. At its apex is a slight elevation, the supraglenoid tuberosity, to which the long head of the biceps brachii is attached.

The anatomic neck of the scapula is the slightly constricted portion which surrounds the head and is more distinct below and behind than above and in front. The surgical neck of the scapula passes directly medial to the base of the coracoid process.

There are three borders of the scapula:

The superior border is the shortest and thinnest; it is concave, and extends from the superior angle to the base of the coracoid process. It is referred to as the cranial border in animals.

At its lateral part is a deep, semicircular notch, the scapular notch, formed partly by the base of the coracoid process. This notch is converted into a foramen by the superior transverse scapular ligament, and serves for the passage of the suprascapular nerve; sometimes the ligament is ossified.

The adjacent part of the superior border affords attachment to the omohyoideus.

The axillary border (or "lateral border") is the thickest of the three. It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle. It is referred to as the caudal border in animals.

It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle.

Immediately below the glenoid cavity is a rough impression, the infraglenoid tuberosity, about 2.5 cm (1 in). in length, which gives origin to the long head of the triceps brachii; in front of this is a longitudinal groove, which extends as far as the lower third of this border, and affords origin to part of the subscapularis.

The inferior third is thin and sharp, and serves for the attachment of a few fibers of the teres major behind, and of the subscapularis in front.

The medial border (also called the vertebral border or medial margin) is the longest of the three borders, and extends from the superior angle to the inferior angle.[8] In animals it is referred to as the dorsal border.

Four muscles attach to the medial border. Serratus anterior has a long attachment on the anterior lip. Three muscles insert along the posterior lip, the levator scapulae (uppermost), rhomboid minor (middle), and to the rhomboid major (lower middle).[8]

Figure 5 : Plan of ossification of the scapula. From seven centers.

The scapula is ossified from 7 or more centers: one for the body, two for the coracoid process, two for the acromion, one for the vertebral border, and one for the inferior angle. Ossification of the body begins about the second month of fetal life, by an irregular quadrilateral plate of bone forming, immediately behind the glenoid cavity. This plate extends to form the chief part of the bone, the scapular spine growing up from its dorsal surface about the third month. Ossification starts as membranous ossification before birth. After birth, the cartilaginous components would undergo endochondral ossification. The larger part of the scapula undergoes membranous ossification. Some of the outer parts of the scapula are cartilaginous at birth, and would therefore undergo endochondral ossification.

At birth, a large part of the scapula is osseous, but the glenoid cavity, the coracoid process, the acromion, the vertebral border and the inferior angle are cartilaginous. From the 15th to the 18th month after birth, ossification takes place in the middle of the coracoid process, which as a rule becomes joined with the rest of the bone about the 15th year.

Between the 14th and 20th years, the remaining parts ossify in quick succession, and usually in the following order: first, in the root of the coracoid process, in the form of a broad scale; secondly, near the base of the acromion; thirdly, in the inferior angle and contiguous part of the vertebral border; fourthly, near the outer end of the acromion; fifthly, in the vertebral border. The base of the acromion is formed by an extension from the spine; the two nuclei of the acromion unite, and then join with the extension from the spine. The upper third of the glenoid cavity is ossified from a separate center (sub coracoid), which appears between the 10th and 11th years and joins between the 16th and the 18th years. Further, an epiphysial plate appears for the lower part of the glenoid cavity, and the tip of the coracoid process frequently has a separate nucleus. These various epiphyses are joined to the bone by the 25th year.

Failure of bony union between the acromion and spine sometimes occurs (see os acromiale), the junction being effected by fibrous tissue, or by an imperfect articulation; in some cases of supposed fracture of the acromion with ligamentous union, it is probable that the detached segment was never united to the rest of the bone.

"In terms of comparative anatomy the human scapula represents two bones that have become fused together; the (dorsal) scapula proper and the (ventral) coracoid. The epiphyseal line across the glenoid cavity is the line of fusion. They are the counterparts of the ilium and ischium of the pelvic girdle."

-  R. J. Last - 'Last's Anatomy

The following muscles attach to the scapula:

Movements of the scapula are brought about by the scapular muscles. The scapula can perform six actions:

A winged scapula (left)

Left scapula, anterior surface. Anatomic neck: red, Surgical neck: purple

Because of its sturdy structure and protected location, fractures of the scapula are uncommon. When they do occur, they are an indication that severe chest trauma has occurred. Scapular fractures involving the neck of the scapula have two patterns. One (rare) type of fracture is through the anatomical neck of the scapula. The other more common type of fracture is through the surgical neck of the scapula. The surgical neck exits medial to the coracoid process.

An abnormally protruding inferior angle of the scapula is known as a winged scapula and can be caused by paralysis of the serratus anterior muscle. In this condition the sides of the scapula nearest the spine are positioned outward and backward. The appearance of the upper back is said to be wing-like. In addition, any condition causing weakness of the serratus anterior muscle may cause scapular "winging".

The scapula plays an important role in shoulder impingement syndrome.

Abnormal scapular function is called scapular dyskinesis. One action the scapula performs during a throwing or serving motion is elevation of the acromion process in order to avoid impingement of the rotator cuff tendons. If the scapula fails to properly elevate the acromion, impingement may occur during the cocking and acceleration phase of an overhead activity. The two muscles most commonly inhibited during this first part of an overhead motion are the serratus anterior and the lower trapezius. These two muscles act as a force couple within the glenohumeral joint to properly elevate the acromion process, and if a muscle imbalance exists, shoulder impingement may develop.

Other conditions associated with scapular dyskenesis include thoracic outlet syndrome and the related pectoralis minor syndrome.

The name scapula as synonym of shoulder blade is of Latin origin. It is commonly used in medical English and is part of the current official Latin nomenclature, Terminologia Anatomica. Shoulder blade is the colloquial name for this bone.[citation needed ]

Scapulae, spine and ribs of Eptesicus fuscus (Big Brown Bat).

In fish, the scapular blade is a structure attached to the upper surface of the articulation of the pectoral fin, and is accompanied by a similar coracoid plate on the lower surface. Although sturdy in cartilagenous fish, both plates are generally small in most other fish, and may be partially cartilagenous, or consist of multiple bony elements.

In the early tetrapods, these two structures respectively became the scapula and a bone referred to as the procoracoid (commonly called simply the " coracoid", but not homologous with the mammalian structure of that name). In amphibians and reptiles (birds included), these two bones are distinct, but together form a single structure bearing many of the muscle attachments for the forelimb. In such animals, the scapula is usually a relatively simple plate, lacking the projections and spine that it possesses in mammals. However, the detailed structure of these bones varies considerably in living groups. For example, in frogs, the procoracoid bones may be braced together at the animal's underside to absorb the shock of landing, while in turtles, the combined structure forms a Y-shape in order to allow the scapula to retain a connection to the clavicle (which is part of the shell). In birds, the procoracoids help to brace the wing against the top of the sternum.

In the fossil therapsids, a third bone, the true coracoid, formed just behind the procoracoid. The resulting three-boned structure is still seen in modern monotremes, but in all other living mammals, the procoracoid has disappeared, and the coracoid bone has fused with the scapula, to become the coracoid process. These changes are associated with the upright gait of mammals, compared with the more sprawling limb arrangement of reptiles and amphibians; the muscles formerly attached to the procoracoid are no longer required. The altered musculature is also responsible for the alteration in the shape of the rest of the scapula; the forward margin of the original bone became the spine and acromion, from which the main shelf of the shoulder blade arises as a new structure.

In dinosaurs the main bones of the pectoral girdle were the scapula (shoulder blade) and the coracoid, both of which directly articulated with the clavicle. The clavicle was present in saurischian dinosaurs but largely absent in ornithischian dinosaurs. The place on the scapula where it articulated with the humerus (upper bone of the forelimb) is called the glenoid. The scapula serves as the attachment site for a dinosaur's back and forelimb muscles.[citation needed ]

Nickel, Schummer, & Seiferle; Lehrbuch der Anatomie der Haussäugetiere.

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The scapula ( pl.: scapulae or scapulas), also known as the shoulder blade, is the bone that connects the humerus (upper arm bone) with the clavicle (collar bone). Like their connected bones, the scapulae are paired, with each scapula on either side of the body being roughly a mirror image of the other.

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25. ribs- they attach to the thoracic vertebrae on the dorsal surface of the body

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25. ribs- they attach to the thoracic vertebrae on the dorsal surface of the body

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In vertebrate anatomy, ribs ( Latin: costae) are the long curved bones which form the rib cage, part of the axial skeleton. In most tetrapods, ribs surround the chest, enabling the lungs to expand and thus facilitate breathing by expanding the chest cavity. They serve to protect the lungs, heart, and other internal organs of the thorax. In some animals, especially snakes, ribs may provide support and protection for the entire body.

Rib details

Human ribs are flat bones that form part of the rib cage to help protect internal organs. Humans usually have 24 ribs, in 12 pairs. 1 in 500 people have an extra rib known as a cervical rib. People may have a cervical rib on the right, left or both sides. All are attached at the back to the thoracic vertebrae and are numbered from 1 to 12 according to the vertebrae to which they attach. The first rib is attached to thoracic vertebra 1 (T1). At the front of the body, most of the ribs are joined by costal cartilage to the sternum. Ribs connect to vertebrae at the costovertebral joints.

The parts of a rib includes the head, neck, body (or shaft), tubercle, and angle.

The head of the rib lies next to a vertebra. The ribs connect to the vertebrae with two costovertebral joints, one on the head and one on the neck. The head of the rib has a superior and an inferior articulating region, separated by a crest. These articulate with the superior and inferior costal facets on the connecting vertebrae. The crest gives attachment to the intra-articulate ligament that joins the rib to the vertebra of the same number, at the intervertebral disc. Another ligament, the radiate ligament joins the head of the rib to both the body of the upper vertebra and to the body of the lower vertebra. The smaller middle part of the ligament connects to the intervertebral disc. This plane joint is known as the articulation of the head of the rib.

The other costovertebral joint is that between the tubercle on the neck and the transverse process of the joining thoracic vertebra of the same rib number, and this is known as the costotransverse joint. The superior costotransverse ligament attaches from the non-articular facet of the tubercle to the transverse process of the vertebra.

The neck of the rib is a flattened part that extends laterally from the head. The neck is about 3 cm long. Its anterior surface is flat and smooth, whilst its posterior is perforated by numerous foramina and its surface rough, to give attachment to the ligament of the neck. Its upper border presents a rough crest ( crista colli costae) for the attachment of the anterior costotransverse ligament; its lower border is rounded.

A tubercle of rib on the posterior surface of the neck of the rib, has two facets (surfaces) one articulating and one non-articulating. The articular facet, is small and oval and is the lower and more medial of the two, and connects to the transverse costal facet on the thoracic vertebra of the same rib number. The transverse costal facet is on the end of the transverse process of the lower of the two vertebrae to which the head is connected. The non-articular portion is a rough elevation and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper ribs than in the lower ribs.

X-ray image of human chest, with ribs labelled

The first seven sets of ribs, known as " true ribs", are attached to the sternum by the costal cartilages. The first rib is unique and easier to distinguish than other ribs. It is a short, flat, C-shaped bone, and attaches to the manubrium. The vertebral attachment can be found just below the neck at the first thoracic vertebra, and the majority of this bone can be found above the level of the clavicle. Ribs 2 through 7 then become longer and less curved as they progress downwards. The following five sets are known as " false ribs", three of these sharing a common cartilaginous connection to the sternum, while the last two (eleventh and twelfth ribs) are termed floating ribs. They are attached to the vertebrae only, and not to the sternum or cartilage coming off of the sternum.

In general, human ribs increase in length from ribs 1 through 7 and decrease in length again through rib 12. Along with this change in size, the ribs become progressively oblique (slanted) from ribs 1 through 9, then less slanted through rib 12.

The rib cage is separated from the lower abdomen by the thoracic diaphragm which controls breathing. When the diaphragm contracts, the thoracic cavity is expanded, reducing intra-thoracic pressure and drawing air into the lungs. This happens through one of two actions (or a mix of the two): when the lower ribs the diaphragm connects to are stabilized by muscles and the central tendon is mobile, when the muscle contracts the central tendon is drawn down, compressing the cavity underneath and expanding the thoracic cavity downward. When the central tendon is stabilized and the lower ribs are mobile, a contraction of the diaphragm elevates the ribs, which works in conjunction with other muscles to expand the thoracic indent upward.

Early in the developing embryo, somites form and soon subdivide into three mesodermal components - the myotome, dermatome, and the sclerotome. The vertebrae and ribs develop from the sclerotomes.

During the fourth week ( fertilization age) costal processes have formed on the vertebral bodies. These processes are small, lateral protrusions of mesenchyme that develop in association with the vertebral arches. During the fifth week the costal processes on the thoracic vertebrae become longer to form the ribs. In the sixth week, the costovertebral joints begin to develop and separate the ribs from the vertebrae. The first seven pairs of ribs, the true ribs join at the front to the sternal bars. By the fetal stage the sternal bars have completely fused.

The ribs begin as cartilage that later ossifies - a process called endochondral ossification. Primary ossification centers are located near the angle of each rib, and ossification continues in the direction away from the head and neck. During adolescence secondary ossification centers are formed in the tubercles and heads of the ribs.

Skeleton of a dog showing the location of the ribs

Rib cage of the big brown bat (Eptesicus fuscus)

In jawed fish, there are often two sets of ribs attached to the vertebral column. One set, the dorsal ribs, are found in the dividing septum between the upper and lower parts of the main muscle segments, projecting roughly sideways from the vertebral column. The second set, the ventral ribs arise from the vertebral column just below the dorsal ribs, and enclose the lower body, often joining at the tips. Not all species possess both types of rib, with the dorsal ribs being most commonly absent. Sharks, for example, have no dorsal ribs, and only very short ventral ribs. In some teleosts, there may be additional rib-like bones within the muscle mass.

Tetrapods, however, only ever have a single set of ribs which are probably homologous with the dorsal ribs of fishes. In the earlier choanates, every vertebra bore a pair of ribs, although those on the thoracic vertebrae are typically the longest. The sacral ribs were stout and short, since they formed part of the pelvis, connecting the backbone to the hip bones.

In most true tetrapods, many of these early ribs have been lost, and in living amphibians and reptiles, there is great variation in rib structure and number. For example, turtles have only eight pairs of ribs, which are developed into a bony or cartilaginous carapace and plastron, while snakes have numerous ribs running along the full length of their trunk. Frogs typically have no ribs, aside from a sacral pair, which form part of the pelvis.

In birds, ribs are present as distinct bones only on the thoracic region, although small fused ribs are present on the cervical vertebrae. The thoracic ribs of birds possess a wide projection to the rear; this uncinate process is an attachment for the shoulder muscles. Usually dogs have 26 ribs. Mammals usually also only have distinct ribs on the thoracic vertebra, although fixed cervical ribs are also present in monotremes. In therian mammals, the cervical and lumbar ribs are found only as tiny remnants fused to the vertebrae, where they are referred to as transverse processes. In general, the structure and number of the true ribs in humans is similar to that in other mammals. Unlike reptiles, caudal ribs are never found in mammals.

Ribs as food are widely used from many animals, such as cows, pigs, hogs, sheep and pandas. The ribs are the less meaty part of the meat chop and they are often cooked as part of a slab; five or more is known as a rack, as in a rack of lamb. Short ribs are ribs of beef either served singly or several as a plate. A rib steak from beef is a popular choice used in many cuisines. Pork ribs, including spare ribs are popular in European and Asian cuisine.

Human ribs (shown in red). It consists of 24 ribs. Left and right of first rib to twelfth rib.

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In vertebrate anatomy, ribs ( Latin: costae) are the long curved bones which form the rib cage, part of the axial skeleton. In most tetrapods, ribs surround the chest, enabling the lungs to expand and thus facilitate breathing by expanding the chest cavity. They serve to protect the lungs, heart, and other internal organs of the thorax.

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24. red marrow- Found in certain bones, such as the vertebrae, ribs, sternum, and cranium  

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24. red marrow- Found in certain bones, such as the vertebrae, ribs, sternum, and cranium  

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Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow.

Human marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of hematopoietic cells, including both myeloid and lymphoid lineages, are created in bone marrow; however, lymphoid cells must migrate to other lymphoid organs (e.g. thymus) in order to complete maturation.

Bone marrow transplants can be conducted to treat severe diseases of the bone marrow, including certain forms of cancer such as leukemia. Several types of stem cells are related to bone marrow. Hematopoietic stem cells in the bone marrow can give rise to hematopoietic lineage cells, and mesenchymal stem cells, which can be isolated from the primary culture of bone marrow stroma, can give rise to bone, adipose, and cartilage tissue.

The composition of marrow is dynamic, as the mixture of cellular and non-cellular components (connective tissue) shifts with age and in response to systemic factors. In humans, marrow is colloquially characterized as "red" or "yellow" marrow ( Latin: medulla ossium rubra, Latin: medulla ossium flava, respectively) depending on the prevalence of hematopoietic cells vs fat cells. While the precise mechanisms underlying marrow regulation are not understood, compositional changes occur according to stereotypical patterns. For example, a newborn baby's bones exclusively contain hematopoietically active "red" marrow, and there is a progressive conversion towards "yellow" marrow with age. In adults, red marrow is found mainly in the central skeleton, such as the pelvis, sternum, cranium, ribs, vertebrae and scapulae, and variably found in the proximal epiphyseal ends of long bones such as the femur and humerus. In circumstances of chronic hypoxia, the body can convert yellow marrow back to red marrow to increase blood cell production.

Bone marrow aspirate showing normal "trilineage hematopoiesis": myelomonocytic cells (an eosinophil myelocyte marked), erythroid cells (an orthochromatic erythroblast marked), and megakaryocytic cells

Hematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirate

At the cellular level, the main functional component of bone marrow includes the progenitor cells which are destined to mature into blood and lymphoid cells. Human marrow produces approximately 500 billion blood cells per day. Marrow contains hematopoietic stem cells which give rise to the three classes of blood cells that are found in circulation: white blood cells (leukocytes), red blood cells (erythrocytes), and platelets (thrombocytes).

The stroma of the bone marrow includes all tissue not directly involved in the marrow's primary function of hematopoiesis. Stromal cells may be indirectly involved in hematopoiesis, providing a microenvironment that influences the function and differentiation of hematopoietic cells. For instance, they generate colony stimulating factors, which have a significant effect on hematopoiesis. Cell types that constitute the bone marrow stroma include:

The bone marrow stroma contains mesenchymal stem cells (MSCs), which are also known as marrow stromal cells. These are multipotent stem cells that can differentiate into a variety of cell types. MSCs have been shown to differentiate, in vitro or in vivo, into osteoblasts, chondrocytes, myocytes, marrow adipocytes and beta-pancreatic islets cells.

The blood vessels of the bone marrow constitute a barrier, inhibiting immature blood cells from leaving the marrow. Only mature blood cells contain the membrane proteins, such as aquaporin and glycophorin, that are required to attach to and pass the blood vessel endothelium. Hematopoietic stem cells may also cross the bone marrow barrier, and may thus be harvested from blood.

The red bone marrow is a key element of the lymphatic system, being one of the primary lymphoid organs that generate lymphocytes from immature hematopoietic progenitor cells. The bone marrow and thymus constitute the primary lymphoid tissues involved in the production and early selection of lymphocytes. Furthermore, bone marrow performs a valve-like function to prevent the backflow of lymphatic fluid in the lymphatic system.

Biological compartmentalization is evident within the bone marrow, in that certain cell types tend to aggregate in specific areas. For instance, erythrocytes, macrophages, and their precursors tend to gather around blood vessels, while granulocytes gather at the borders of the bone marrow.

People have used animal bone-marrow in cuisine worldwide for millennia, as in the famed Milanese Ossobuco.

The normal bone marrow architecture can be damaged or displaced by aplastic anemia, malignancies such as multiple myeloma, or infections such as tuberculosis, leading to a decrease in the production of blood cells and blood platelets. The bone marrow can also be affected by various forms of leukemia, which attacks its hematologic progenitor cells. Furthermore, exposure to radiation or chemotherapy will kill many of the rapidly dividing cells of the bone marrow, and will therefore result in a depressed immune system. Many of the symptoms of radiation poisoning are due to damage sustained by the bone marrow cells.

To diagnose diseases involving the bone marrow, a bone marrow aspiration is sometimes performed. This typically involves using a hollow needle to acquire a sample of red bone marrow from the crest of the ilium under general or local anesthesia.

Bone marrow derived stem cells have a wide array of application in regenerative medicine.

Medical imaging may provide a limited amount of information regarding bone marrow. Plain film x-rays pass through soft tissues such as marrow and do not provide visualization, although any changes in the structure of the associated bone may be detected. CT imaging has somewhat better capacity for assessing the marrow cavity of bones, although with low sensitivity and specificity. For example, normal fatty "yellow" marrow in adult long bones is of low density (-30 to -100 Hounsfield units), between subcutaneous fat and soft tissue. Tissue with increased cellular composition, such as normal "red" marrow or cancer cells within the medullary cavity will measure variably higher in density.

MRI is more sensitive and specific for assessing bone composition. MRI enables assessment of the average molecular composition of soft tissues and thus provides information regarding the relative fat content of marrow. In adult humans, "yellow" fatty marrow is the dominant tissue in bones, particularly in the (peripheral) appendicular skeleton. Because fat molecules have a high T1-relaxivity, T1-weighted imaging sequences show "yellow" fatty marrow as bright (hyperintense). Furthermore, normal fatty marrow loses signal on fat-saturation sequences, in a similar pattern to subcutaneous fat.

When "yellow" fatty marrow becomes replaced by tissue with more cellular composition, this change is apparent as decreased brightness on T1-weighted sequences. Both normal "red" marrow and pathologic marrow lesions (such as cancer) are darker than "yellow" marrow on T1-weight sequences, although can often be distinguished by comparison with the MR signal intensity of adjacent soft tissues. Normal "red" marrow is typically equivalent or brighter than skeletal muscle or intervertebral disc on T1-weighted sequences.

Fatty marrow change, the inverse of red marrow hyperplasia, can occur with normal aging, though it can also be seen with certain treatments such as radiation therapy. Diffuse marrow T1 hypointensity without contrast enhancement or cortical discontinuity suggests red marrow conversion or myelofibrosis. Falsely normal marrow on T1 can be seen with diffuse multiple myeloma or leukemic infiltration when the water to fat ratio is not sufficiently altered, as may be seen with lower grade tumors or earlier in the disease process.

A Wright's-stained bone marrow aspirate smear from a patient with leukemia

Bone marrow examination is the pathologic analysis of samples of bone marrow obtained via biopsy and bone marrow aspiration. Bone marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, anemia, and pancytopenia. The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells. While much information can be gleaned by testing the blood itself (drawn from a vein by phlebotomy), it is sometimes necessary to examine the source of the blood cells in the bone marrow to obtain more information on hematopoiesis; this is the role of bone marrow aspiration and biopsy.

The ratio between myeloid series and erythroid cells is relevant to bone marrow function, and also to diseases of the bone marrow and peripheral blood, such as leukemia and anemia. The normal myeloid-to-erythroid ratio is around 3:1; this ratio may increase in myelogenous leukemias, decrease in polycythemias, and reverse in cases of thalassemia.

A bone marrow harvest in progress

The preferred sites for the procedure

In a bone marrow transplant, hematopoietic stem cells are removed from a person and infused into another person ( allogenic) or into the same person at a later time ( autologous). If the donor and recipient are compatible, these infused cells will then travel to the bone marrow and initiate blood cell production. Transplantation from one person to another is conducted for the treatment of severe bone marrow diseases, such as congenital defects, autoimmune diseases or malignancies. The patient's own marrow is first killed off with drugs or radiation, and then the new stem cells are introduced. Before radiation therapy or chemotherapy in cases of cancer, some of the patient's hematopoietic stem cells are sometimes harvested and later infused back when the therapy is finished to restore the immune system.

Bone marrow stem cells can be induced to become neural cells to treat neurological illnesses, and can also potentially be used for the treatment of other illnesses, such as inflammatory bowel disease. In 2013, following a clinical trial, scientists proposed that bone marrow transplantation could be used to treat HIV in conjunction with antiretroviral drugs; however, it was later found that HIV remained in the bodies of the test subjects.

Harvesting

The stem cells are typically harvested directly from the red marrow in the iliac crest, often under general anesthesia. The procedure is minimally invasive and does not require stitches afterwards. Depending on the donor's health and reaction to the procedure, the actual harvesting can be an outpatient procedure, or can require 1-2 days of recovery in the hospital.

Another option is to administer certain drugs that stimulate the release of stem cells from the bone marrow into circulating blood. An intravenous catheter is inserted into the donor's arm, and the stem cells are then filtered out of the blood. This procedure is similar to that used in blood or platelet donation. In adults, bone marrow may also be taken from the sternum, while the tibia is often used when taking samples from infants. In newborns, stem cells may be retrieved from the umbilical cord.

Using quantitative Polymerase Chain Reaction (qPCR) and Next-generation Sequencing (NGS) a maximum of five DNA viruses per individual have been identified. Included were several herpesviruses, hepatitis B virus, Merkel cell polyomavirus, and human papillomavirus 31. Given the reactivation and/or oncogenic potential of these viruses, their repercussion on hematopoietic and malignant disorders calls for further studies.

Bone marrow may have first evolved in Eusthenopteron, a species of prehistoric fish with close links to early tetrapods.

The earliest fossilised evidence of bone marrow was discovered in 2014 in Eusthenopteron, a lobe-finned fish which lived during the Devonian period approximately 370 million years ago. Scientists from Uppsala University and the European Synchrotron Radiation Facility used X-ray synchrotron microtomography to study the fossilised interior of the skeleton's humerus, finding organised tubular structures akin to modern vertebrate bone marrow. Eusthenopteron is closely related to the early tetrapods, which ultimately evolved into the land-dwelling mammals and lizards of the present day.

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Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.

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23. radius- lower arm on thumb side that rotates around the ulna to allow the hand to turn freely 

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23. radius- lower arm on thumb side that rotates around the ulna to allow the hand to turn freely 

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22. phalanges- three on each finger and two on the thumb

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22. phalanges- three on each finger and two on the thumb

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In the foot, the proximal phalanges have a body that is compressed from side to side, convex above, and concave below. The base is concave, and the head presents a trochlear surface for articulation with the second phalanx. The middle are remarkably small and short, but rather broader than the proximal.

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21. periosteum- contains blood vessels, lymph nodes, and osteoblasts

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21. periosteum- contains blood vessels, lymph nodes, and osteoblasts

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Top Contributors - Shejza Mino, Lucinda hampton, Kim Jackson, Vidya Acharya and Wendy Snyders  

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In human anatomy, the metacarpal bones or metacarpus, form the intermediate part of the skeletal hand located between the phalanges of the fingers and the carpal bones of the wrist which forms the connection to the forearm. The metacarpal bones are equivalent to the metatarsal bones in the foot.

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16. medullary canal- A cavity in the diaphysis 

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16. medullary canal- A cavity in the diaphysis 

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From Wikipedia, the free encyclopedia

The medullary cavity ( medulla, innermost part) is the central cavity of bone shafts where red bone marrow and/or yellow bone marrow ( adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.

Located in the main shaft of a long bone ( diaphysis) (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane ( endosteum).

This area is involved in the formation of red blood cells and white blood cells, and the calcium supply for bird eggshells. The area has been detected in fossil bones despite the fossilization process.

Intramedullary is a medical term meaning the inside of a bone. Examples include intramedullary rods used to treat bone fractures in orthopedic surgery and intramedullary tumors occurring in some forms of cancer or benign tumors such as an enchondroma.

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From Wikipedia, the free encyclopedia The medullary cavity ( medulla, innermost part) is the central cavity of bone shafts where red bone marrow and/or yellow bone marrow ( adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.

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15. ligaments- help hold long bones together at joints 

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15. ligaments- help hold long bones together at joints 

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14. joints- areas where two bones join together 

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14. joints- areas where two bones join together 

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A joint or articulation (or articular surface) is the connection made between bones in the body which link the skeletal system into a functional whole. They are constructed to allow for different degrees and types of movement.

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The humerus (, Plural: humeri) is a long bone in the arm or forelimb that runs from the shoulder to the elbow. It connects the scapula and the two bones of the lower arm, the radius and ulna, and consists of three sections.

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12. foramina-  openings in bones that allow nerves and blood vessels to enter or leave the bones

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12. foramina-  openings in bones that allow nerves and blood vessels to enter or leave the bones

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Cranial Foramina - Foramen Ovale - Skull - TeachMeAnatomy

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In the skull base, there are numerous foramina that transmit cranial nerves, blood vessels and other structures - these are collectively referred to as the cranial foramina.

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11. fontanels- "soft spots" allow for the enlargement in the skull as brain growth occurs  

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11. fontanels- "soft spots" allow for the enlargement in the skull as brain growth occurs  

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A fontanelle (or fontanel) (colloquially, soft spot) is an anatomical feature of the infant human skull comprising soft membranous gaps ( sutures) between the cranial bones that make up the calvaria of a fetus or an infant. Fontanelles allow for stretching and deformation of the neurocranium both during birth and later as the brain expands faster than the surrounding bone can grow. Premature complete ossification of the sutures is called craniosynostosis.

After infancy, the anterior fontanelle is known as the bregma.

An infant's skull consists of five main bones: two frontal bones, two parietal bones, and one occipital bone. These are joined by fibrous sutures, which allow movement that facilitates childbirth and brain growth.

Posterior fontanelle is triangle-shaped. It lies at the junction between the sagittal suture and lambdoid suture. At birth, the skull features a small posterior fontanelle with an open area covered by a tough membrane, where the two parietal bones adjoin the occipital bone (at the lambda). The posterior fontanelles ossify within 6-8 weeks after birth. This is called intramembranous ossification. The mesenchymal connective tissue turns into bone tissue.

Anterior fontanelle is a diamond-shaped membrane-filled space located between the two frontal and two parietal bones of the developing fetal skull. It persists until approximately 18 months after birth. It is at the junction of the coronal suture and sagittal suture. The fetal anterior fontanelle may be palpated until 18 months. In cleidocranial dysostosis, however, it is often late in closing at 8-24 months or may never close. Examination of an infant includes palpating the anterior fontanelle.

Two smaller fontanelles are located on each side of the head, more anteriorly the sphenoidal or anterolateral fontanelle (between the sphenoid, parietal, temporal, and frontal bones) and more posteriorly the mastoid or posterolateral fontanelle (between the temporal, occipital, and parietal bones).

During birth, fontanelles enable the bony plates of the skull to flex, allowing the child's head to pass through the birth canal. The ossification of the bones of the skull causes the anterior fontanelle to close over by 9 to 18 months. The sphenoidal and posterior fontanelles close during the first few months of life. The closures eventually form the sutures of the neurocranium. Other than the anterior and posterior fontanelles, the mastoid fontanelle and the sphenoidal fontanelle are also significant.

In humans, the sequence of fontanelle closure is as follows:

1. The posterior fontanelle generally closes 2 to 3 months after birth;

2. The sphenoidal fontanelle is the next to close around 6 months after birth;

3. The mastoid fontanelle closes next from 6 to 18 months after birth; and

4. The anterior fontanelle is generally the last to close between 12 and 18 months.

The fontanelle may pulsate, and although the precise cause of this is not known, it is normal and seems to echo the heartbeat, perhaps via the arterial pulse within the brain vasculature, or in the meninges. This pulsating action is how the soft spot got its name - fontanelle is borrowed from the old French word fontenele, which is a diminutive of fontaine, meaning "spring". It is assumed that the term spring is used because of the analogy of the dent in a rock or earth where a spring arises.

Parents may worry that their infant may be more prone to injury at the fontanelles. In fact, although they may colloquially be called "soft-spots", the membrane covering the fontanelles is extremely tough and difficult to penetrate.

Fontanelles allow the infant brain to be imaged using ultrasonography. Once they are closed, most of the brain is inaccessible to ultrasound imaging, because the bony skull presents an acoustic barrier.

A very tense or bulging anterior fontanelle indicates raised intracranial pressure. Increased cranial pressure in infants may cause the fontanelles to bulge or the head to begin to enlarge abnormally. It can occur due to:

A sunken (also called "depressed") fontanelle indicates dehydration or malnutrition.

Anterior fontanelle of a 1-month-old infant

The fontanelles may be enlarged, may be slow to close, or may never close, most commonly due to causes like:

Rarer causes include:

Sometimes there is a third bigger fontanelle other than posterior and anterior ones in a newborn. In one study, the frequency of third fontanelles in an unselected population of newborn infants was 6.3%. It is very common in Down syndrome and some congenital infections. If present, the physician should rule out serious conditions associated with the third fontanelle.

In apes the fontanelles fuse soon after birth. In chimpanzees the anterior fontanelle is fully closed by 3 months of age.

One of the more serious problems that can affect canines is known as an "open fontanelle", which occurs when the skull bones at the top of the head fail to close. The problem is often found in conjunction with hydrocephalus, which is a condition in which too much fluid is found within and around the brain, placing pressure on the brain and surrounding tissues. Often the head will appear dome-shaped, and the open fontanelle is noticeable as a "soft spot" on the top of the dog's head. The fluid-filled spaces within the brain, known as ventricles, also become swollen. The increased pressure damages or prevents the development of brain tissue.

Not all open fontanelles are connected with hydrocephalus. In many young dogs the skull bones are not fused at birth, but instead will close slowly over a three- to six-month period. Occasionally these bones fail to close, but the dog is still healthy. In these cases, however, the dog's owners need to be very careful, since any injury or bumps to the animal's head could cause significant brain damage, as well as conditions like epilepsy.

An open fontanelle, known as a molera, is a recognized feature of the Chihuahua breed. The American Kennel Club breed standard states that the skull of the Chihuahua should be domed, with or without the molera being present. However, the Fédération Cynologique Internationale (FCI) standard for the Chihuahua lists an open fontanelle as a disqualification.

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A fontanelle (or fontanel) (colloquially, soft spot) is an anatomical feature of the infant human skull comprising soft membranous gaps ( sutures) between the cranial bones that make up the calvaria of a fetus or an infant. Fontanelles allow for stretching and deformation of the neurocranium both during birth and later as the brain expands faster than the surrounding bone can grow.

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10. fibula- the slender smaller bone of the lower leg that attaches to the proximal end of the tibia

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10. fibula- the slender smaller bone of the lower leg that attaches to the proximal end of the tibia

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The fibula or calf bone is a leg bone located on the lateral side of the tibia, with which it is connected above and below. It is the smaller of the two bones and in proportion to its length, the slenderest of all the long bones. Its upper extremity is small, placed toward the back of the head of the tibia, below the level of the knee joint, and excluded from the formation of this joint. Its lower extremity inclines a little forward, so as to be on a plane anterior to that of the upper end; it projects below the tibia, and forms the lateral part of the ankle-joint.

The bone has the following components:

The blood supply is important for planning free tissue transfer because the fibula is commonly used to reconstruct the mandible. The shaft is supplied in its middle third by a large nutrient vessel from the fibular artery. It is also perfused from its periosteum which receives many small branches from the fibular artery. The proximal head and the epiphysis are supplied by a branch of the anterior tibial artery. In harvesting the bone the middle third is always taken and the ends preserved (4 cm proximally and 6 cm distally)

The fibula is ossified from three centers, one for the shaft, and one for either end. Ossification begins in the body about the eighth week of fetal life, and extends toward the extremities. At birth the ends are cartilaginous.

Ossification commences in the lower end in the second year, and in the upper about the fourth year. The lower epiphysis, the first to ossify, unites with the body about the twentieth year; the upper epiphysis joins about the twenty-fifth year.

The upper extremity or head of the fibula is of an irregular quadrate form, presenting above a flattened articular surface, directed upward, forward, and medialward, for articulation with a corresponding surface on the lateral condyle of the tibia. On the lateral side is a thick and rough prominence continued behind into a pointed eminence, the apex ( styloid process), which projects upward from the posterior part of the head.

The prominence, at its upper and lateral part, gives attachment to the tendon of the biceps femoris and to the fibular collateral ligament of the knee-joint, the ligament dividing the tendon into two parts.

The remaining part of the circumference of the head is rough, for the attachment of muscles and ligaments. It presents in front a tubercle for the origin of the upper and anterior fibers of the peroneus longus, and a surface for the attachment of the anterior ligament of the head; and behind, another tubercle, for the attachment of the posterior ligament of the head and the origin of the upper fibers of the soleus.

The body of the fibula presents four borders - the antero-lateral, the antero-medial, the postero-lateral, and the postero-medial; and four surfaces - anterior, posterior, medial, and lateral.

The antero-lateral border begins above in front of the head, runs vertically downward to a little below the middle of the bone, and then curving somewhat lateralward, bifurcates so as to embrace a triangular subcutaneous surface immediately above the lateral malleolus. This border gives attachment to an intermuscular septum, which separates the extensor muscles on the anterior surface of the leg from the peronaei longus and brevis on the lateral surface.

The antero-medial border, or interosseous crest, is situated close to the medial side of the preceding, and runs nearly parallel with it in the upper third of its extent, but diverges from it in the lower two-thirds. It begins above just beneath the head of the bone (sometimes it is quite indistinct for about 2.5 cm. below the head), and ends at the apex of a rough triangular surface immediately above the articular facet of the lateral malleolus. It serves for the attachment of the interosseous membrane, which separates the extensor muscles in front from the flexor muscles behind.

The postero-lateral border is prominent; it begins above at the apex, and ends below in the posterior border of the lateral malleolus. It is directed lateralward above, backward in the middle of its course, backward, and a little medialward below, and gives attachment to an aponeurosis which separates the peronaei on the lateral surface from the flexor muscles on the posterior surface.

The postero-medial border, sometimes called the oblique line, begins above at the medial side of the head, and ends by becoming continuous with the interosseous crest at the lower fourth of the bone. It is well-marked and prominent at the upper and middle parts of the bone. It gives attachment to an aponeurosis which separates the tibialis posterior from the soleus and flexor hallucis longus.

The anterior surface is the interval between the antero-lateral and antero-medial borders. It is extremely narrow and flat in the upper third of its extent; broader and grooved longitudinally in its lower third; it serves for the origin of three muscles: the extensor digitorum longus, extensor hallucis longus, and peroneus tertius.

The posterior surface is the space included between the postero-lateral and the postero-medial borders; it is continuous below with the triangular area above the articular surface of the lateral malleolus; it is directed backward above, backward and medialward at its middle, directly medialward below. Its upper third is rough, for the origin of the soleus; its lower part presents a triangular surface, connected to the tibia by a strong interosseous ligament; the intervening part of the surface is covered by the fibers of origin of the flexor hallucis longus. Near the middle of this surface is the nutrient foramen, which is directed downward.

The medial surface is the interval included between the antero-medial and the postero-medial borders. It is grooved for the origin of the tibialis posterior.

The lateral surface is the space between the antero-lateral and postero-lateral borders. It is broad, and often deeply grooved; it is directed lateralward in the upper two-thirds of its course, backward in the lower third, where it is continuous with the posterior border of the lateral malleolus. This surface gives origin to the peronaei longus and brevis.

The fibula does not carry any significant load (weight) of the body. It extends past the lower end of the tibia and forms the outer part of the ankle providing stability to this joint. It has grooves for certain ligaments which gives them leverage and multiplies the muscle force. It provides attachment points for the following muscles:

The most common type of fibula fracture is located at the distal end of the bone, and is classified as ankle fracture. In the Danis-Weber classification it has three categories:

Type A: Fracture of the lateral malleolus, distal to the syndesmosis (the connection between the distal ends of the tibia and fibula).

Type B: Fracture of the fibula at the level of the syndesmosis

Type C: Fracture of the fibula proximal to the syndesmosis.

A Maisonneuve fracture is a spiral fracture of the proximal third of the fibula associated with a tear of the distal tibiofibular syndesmosis and the interosseous membrane. There is an associated fracture of the medial malleolus or rupture of the deep deltoid ligament.

An avulsion fracture of the head of the fibula refers to the fracture of the fibular head because of a sudden contraction of the biceps femoris muscle that pulls its site of attachment on the bone. The attachment of the biceps femoris tendon on the fibular head is closely related to the lateral collateral ligament of the knee. Therefore, this ligament is prone to injury in this type of avulsion fracture.

The word can be dated back to c. 1670 to describe a clasp or brooch - see fibula (brooch) - and was first used in English for the smaller bone in the lower leg c. 1706. It derives from Latin fībula, also meaning a clasp or brooch. The bone was so called because it resembles a clasp like a modern safety pin.

Because the fibula bears relatively little weight in comparison with the tibia, it is typically narrower in all but the most primitive tetrapods. In many animals, it still articulates with the posterior part of the lower extremity of the femur, but this feature is frequently lost (as it is in humans). In some animals, the reduction of the fibula has proceeded even further than it has in humans, with the loss of the tarsal articulation, and, in extreme cases (such as the horse), partial fusion with the tibia.

This article incorporates text in the public domain from page 260 of the 20th edition of Gray's Anatomy (1918)

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The fibula or calf bone is a leg bone located on the lateral side of the tibia, with which it is connected above and below. It is the smaller of the two bones and in proportion to its length, the slenderest of all the long bones.

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In anatomy, the thigh is the area between the hip ( pelvis) and the knee. Anatomically, it is part of the lower limb.

The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of bone tissue), and forms a ball and socket joint at the hip, and a modified hinge joint at the knee.

The femur is the only bone in the thigh and serves as an attachment site for all muscles in the thigh. The head of the femur articulates with the acetabulum in the pelvic bone forming the hip joint, while the distal part of the femur articulates with the tibia and patella forming the knee. By most measures, the femur is the strongest bone in the body. The femur is also the longest bone in the body.

The femur is categorised as a long bone and comprises a diaphysis, the shaft (or body) and two epiphyses, the lower extremity and the upper extremity of femur, that articulate with adjacent bones in the hip and knee.

Muscular compartments

In cross-section, the thigh is divided up into three separate compartments, divided by fascia, each containing muscles. These compartments use the femur as an axis and are separated by tough connective tissue membranes (or septa). Each of these compartments has its own blood and nerve supply, and contains a different group of muscles.

Anterior compartment muscles of the thigh include sartorius, and the four muscles that comprise the quadriceps muscles- rectus femoris, vastus medialis, vastus intermedius and vastus lateralis.

Posterior compartment muscles of the thigh are the hamstring muscles, which include semimembranosus, semitendinosus, and biceps femoris.

Medial compartment muscles are pectineus, adductor magnus, adductor longus and adductor brevis, and also gracilis.

Because the major muscles of the thigh are the largest muscles of the body, resistance exercises (strength training) of them stimulate blood flow more than any other localized activity.

Blood supply

Main blood vessels of the thigh.[6]

The arterial supply is by the femoral artery and the obturator artery. The lymphatic drainage closely follows the arterial supply and drains to the lumbar lymphatic trunks on the corresponding side, which in turn drains to the cisterna chyli.

The deep venous system of the thigh consists of the femoral vein, common femoral vein, deep femoral vein, the proximal part of the popliteal vein, and various smaller vessels; these are the site of proximal deep vein thrombosis. The perforating veins connect the deep and the superficial system, which consists of the small and great saphenous veins (the site of varicose veins).

Thigh weakness can result in a positive Gowers' sign on physical examination.

Thigh injury resulting from sports, whether acute or from overuse, can mean significant incapacity to perform. Soft tissue injury can encompass sprains, strains, bruising and tendinitis.

Runner's knee ( patellofemoral pain) is a direct consequence of the kneecap rubbing against the end of the thigh bone ( femur). Tight hamstrings and weak thigh muscles, required to stabilize the knee, increase the risk of developing of runner's knee.

Western societies generally tolerate clothing that displays thighs, such as short shorts and miniskirts. Beachwear and many athleisure styles often display thighs as well. Professional dress codes may require covering up bare thighs.

Many Islamic countries disapprove of or prohibit the display of thighs, especially by women.

Strategic covering or display of thighs is used in popular fashion around the world, such as thigh-high boots and zettai ryoiki.

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In anatomy, the thigh is the area between the hip ( pelvis) and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of bone tissue), and forms a ball and socket joint at the hip, and a modified hinge joint at the knee.

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7. endosteum- A membrane that lines the medullary canal and keeps the yellow marrow in tact

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7. endosteum- A membrane that lines the medullary canal and keeps the yellow marrow in tact

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From Wikipedia, the free encyclopedia

The medullary cavity ( medulla, innermost part) is the central cavity of bone shafts where red bone marrow and/or yellow bone marrow ( adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.

Located in the main shaft of a long bone ( diaphysis) (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane ( endosteum).

This area is involved in the formation of red blood cells and white blood cells, and the calcium supply for bird eggshells. The area has been detected in fossil bones despite the fossilization process.

Intramedullary is a medical term meaning the inside of a bone. Examples include intramedullary rods used to treat bone fractures in orthopedic surgery and intramedullary tumors occurring in some forms of cancer or benign tumors such as an enchondroma.

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From Wikipedia, the free encyclopedia The medullary cavity ( medulla, innermost part) is the central cavity of bone shafts where red bone marrow and/or yellow bone marrow ( adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity.

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From Wikipedia, the free encyclopedia

The diaphysis ( pl.: diaphyses) is the main or midsection (shaft) of a long bone. It is made up of cortical bone and usually contains bone marrow and adipose tissue (fat).

It is a middle tubular part composed of compact bone which surrounds a central marrow cavity which contains red or yellow marrow. In diaphysis, primary ossification occurs.

Ewing sarcoma tends to occur at the diaphysis.

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From Wikipedia, the free encyclopedia The diaphysis ( pl.: diaphyses) is the main or midsection (shaft) of a long bone. It is made up of cortical bone and usually contains bone marrow and adipose tissue (fat). It is a middle tubular part composed of compact bone which surrounds a central marrow cavity which contains red or yellow marrow.

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5. cranium- the spherical structure that surrounds and protects the brain 

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5. cranium- the spherical structure that surrounds and protects the brain 

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The skull is a bony structure that forms the head in vertebrates. It supports the structures of the face and provides a protective cavity for the brain. The skull is composed of two parts: the cranium and the mandible. In humans, these two parts are the neurocranium and the viscerocranium or facial skeleton that includes the mandible as its largest bone. The skull forms the anterior most portion of the skeleton and is a product of cephalisation-housing the brain, and several sensory structures such as the eyes, ears, nose, and mouth. In humans these sensory structures are part of the facial skeleton.

Functions of the skull include protection of the brain, fixing the distance between the eyes to allow stereoscopic vision, and fixing the position of the ears to enable sound localisation of the direction and distance of sounds. In some animals such as horned ungulates, the skull also has a defensive function by providing the mount (on the frontal bone) for the horns.

The English word "skull" is probably derived from Old Norse "skulle", while the Latin word cranium comes from the Greek root κρανίον ( kranion).

The skull is made up of a number of fused flat bones, and contains many foramina, fossae, processes, and several cavities or sinuses. In zoology there are openings in the skull called fenestrae.

The human skull is the bony structure that forms the head in the human skeleton. It supports the structures of the face and forms a cavity for the brain. Like the skulls of other vertebrates, it protects the brain from injury.

The skull consists of three parts, of different embryological origin-the neurocranium, the sutures, and the facial skeleton (also called the membraneous viscerocranium). The neurocranium (or braincase) forms the protective cranial cavity that surrounds and houses the brain and brainstem. The upper areas of the cranial bones form the calvaria (skullcap). The membranous viscerocranium includes the mandible.

The sutures are fairly rigid joints between bones of the neurocranium.

The facial skeleton is formed by the bones supporting the face.

Except for the mandible, all of the bones of the skull are joined together by sutures- synarthrodial (immovable) joints formed by bony ossification, with Sharpey's fibres permitting some flexibility. Sometimes there can be extra bone pieces within the suture known as wormian bones or sutural bones. Most commonly these are found in the course of the lambdoid suture.

The human skull is generally considered to consist of twenty-two bones-eight cranial bones and fourteen facial skeleton bones. In the neurocranium these are the occipital bone, two temporal bones, two parietal bones, the sphenoid, ethmoid and frontal bones.

The bones of the facial skeleton (14) are the vomer, two inferior nasal conchae, two nasal bones, two maxilla, the mandible, two palatine bones, two zygomatic bones, and two lacrimal bones. Some sources count a paired bone as one, or the maxilla as having two bones (as its parts); some sources include the hyoid bone or the three ossicles of the middle ear but the overall general consensus of the number of bones in the human skull is the stated twenty-two.

Some of these bones-the occipital, parietal, frontal, in the neurocranium, and the nasal, lacrimal, and vomer, in the facial skeleton are flat bones.

The skull also contains sinuses, air-filled cavities known as paranasal sinuses, and numerous foramina. The sinuses are lined with respiratory epithelium. Their known functions are the lessening of the weight of the skull, the aiding of resonance to the voice and the warming and moistening of the air drawn into the nasal cavity.

The foramina are openings in the skull. The largest of these is the foramen magnum that allows the passage of the spinal cord as well as nerves and blood vessels.

The many processes of the skull include the mastoid process and the zygomatic processes.

The skull is a complex structure; its bones are formed both by intramembranous and endochondral ossification. The skull roof bones, comprising the bones of the facial skeleton and the sides and roof of the neurocranium, are dermal bones formed by intramembranous ossification, though the temporal bones are formed by endochondral ossification. The endocranium, the bones supporting the brain (the occipital, sphenoid, and ethmoid) are largely formed by endochondral ossification. Thus frontal and parietal bones are purely membranous. The geometry of the skull base and its fossae, the anterior, middle and posterior cranial fossae changes rapidly. The anterior cranial fossa changes especially during the first trimester of pregnancy and skull defects can often develop during this time.

At birth, the human skull is made up of 44 separate bony elements. During development, many of these bony elements gradually fuse together into solid bone (for example, the frontal bone). The bones of the roof of the skull are initially separated by regions of dense connective tissue called fontanelles. There are six fontanelles: one anterior (or frontal), one posterior (or occipital), two sphenoid (or anterolateral), and two mastoid (or posterolateral). At birth these regions are fibrous and moveable, necessary for birth and later growth. This growth can put a large amount of tension on the "obstetrical hinge", which is where the squamous and lateral parts of the occipital bone meet. A possible complication of this tension is rupture of the great cerebral vein. As growth and ossification progress, the connective tissue of the fontanelles is invaded and replaced by bone creating sutures. The five sutures are the two squamous sutures, one coronal, one lambdoid, and one sagittal suture. The posterior fontanelle usually closes by eight weeks, but the anterior fontanel can remain open up to eighteen months. The anterior fontanelle is located at the junction of the frontal and parietal bones; it is a "soft spot" on a baby's forehead. Careful observation will show that you can count a baby's heart rate by observing the pulse pulsing softly through the anterior fontanelle.

The skull in the neonate is large in proportion to other parts of the body. The facial skeleton is one seventh of the size of the calvaria. (In the adult it is half the size). The base of the skull is short and narrow, though the inner ear is almost adult size.

Craniosynostosis is a condition in which one or more of the fibrous sutures in an infant skull prematurely fuses, and changes the growth pattern of the skull. Because the skull cannot expand perpendicular to the fused suture, it grows more in the parallel direction. Sometimes the resulting growth pattern provides the necessary space for the growing brain, but results in an abnormal head shape and abnormal facial features. In cases in which the compensation does not effectively provide enough space for the growing brain, craniosynostosis results in increased intracranial pressure leading possibly to visual impairment, sleeping impairment, eating difficulties, or an impairment of mental development.

A copper beaten skull is a phenomenon wherein intense intracranial pressure disfigures the internal surface of the skull. The name comes from the fact that the inner skull has the appearance of having been beaten with a ball-peen hammer, such as is often used by coppersmiths. The condition is most common in children.

Injuries to the brain can be life-threatening. Normally the skull protects the brain from damage through its hard unyieldingness; the skull is one of the least deformable structures found in nature with it needing the force of about 1 ton to reduce the diameter of the skull by 1 cm. In some cases, however, of head injury, there can be raised intracranial pressure through mechanisms such as a subdural haematoma. In these cases the raised intracranial pressure can cause herniation of the brain out of the foramen magnum ("coning") because there is no space for the brain to expand; this can result in significant brain damage or death unless an urgent operation is performed to relieve the pressure. This is why patients with concussion must be watched extremely carefully.

Dating back to Neolithic times, a skull operation called trepanning was sometimes performed. This involved drilling a burr hole in the cranium. Examination of skulls from this period reveals that the patients sometimes survived for many years afterward. It seems likely that trepanning was also performed purely for ritualistic or religious reasons. Nowadays this procedure is still used but is normally called a craniectomy.

In March 2013, for the first time in the U.S., researchers replaced a large percentage of a patient's skull with a precision, 3D-printed polymer implant. About 9 months later, the first complete cranium replacement with a 3D-printed plastic insert was performed on a Dutch woman. She had been suffering from hyperostosis, which increased the thickness of her skull and compressed her brain.

A study conducted in 2018 by the researchers of Harvard Medical School in Boston, funded by National Institutes of Health (NIH) suggested that instead of travelling via blood, there are "tiny channels" in the skull through which the immune cells combined with the bone marrow reach the areas of inflammation after an injury to the brain tissues.

Surgical alteration of sexually dimorphic skull features may be carried out as a part of facial feminization surgery, a set of reconstructive surgical procedures that can alter male facial features to bring them closer in shape and size to typical female facial features. These procedures can be an important part of the treatment of transgender people for gender dysphoria.

Artificial cranial deformation is a largely historical practice of some cultures. Cords and wooden boards would be used to apply pressure to an infant's skull and alter its shape, sometimes quite significantly. This procedure would begin just after birth and would be carried on for several years.[citation needed ]

Like the face, the skull and teeth can also indicate a person's life history and origin. Forensic scientists and archaeologists use metric and nonmetric traits to estimate what the bearer of the skull looked like. When a significant amount of bones are found, such as at Spitalfields in the UK and Jōmon shell mounds in Japan, osteologists can use traits, such as the proportions of length, height and width, to know the relationships of the population of the study with other living or extinct populations.[citation needed ]

The German physician Franz Joseph Gall in around 1800 formulated the theory of phrenology, which attempted to show that specific features of the skull are associated with certain personality traits or intellectual capabilities of its owner. His theory is now considered to be pseudoscientific.[citation needed ]

In the mid-nineteenth century, anthropologists found it crucial to distinguish between male and female skulls. An anthropologist of the time, James McGrigor Allan, argued that the female brain was similar to that of an animal. This allowed anthropologists to declare that women were in fact more emotional and less rational than men. McGrigor then concluded that women's brains were more analogous to infants, thus deeming them inferior at the time. To further these claims of female inferiority and silence the feminists of the time, other anthropologists joined in on the studies of the female skull. These cranial measurements are the basis of what is known as craniology. These cranial measurements were also used to draw a connection between women and black people.

Research has shown that while in early life there is little difference between male and female skulls, in adulthood male skulls tend to be larger and more robust than female skulls, which are lighter and smaller, with a cranial capacity about 10 percent less than that of the male. However, later studies show that women's skulls are slightly thicker and thus men may be more susceptible to head injury than women.

Male skulls can have more prominent supraorbital ridges, a more prominent glabella, and more prominent temporal lines. Female skulls generally have rounder orbits, and narrower jaws. Male skulls on average have larger, broader palates, squarer orbits, larger mastoid processes, larger sinuses, and larger occipital condyles than those of females. Male mandibles typically have squarer chins and thicker, rougher muscle attachments than female mandibles.[citation needed ]

The cephalic index is the ratio of the width of the head, multiplied by 100 and divided by its length (front to back). The index is also used to categorize animals, especially dogs and cats. The width is usually measured just below the parietal eminence, and the length from the glabella to the occipital point.

Humans may be:

The skull of fishes is formed from a series of only loosely connected bones. Lampreys and sharks only possess a cartilaginous endocranium, with both the upper and lower jaws being separate elements. Bony fishes have additional dermal bone, forming a more or less coherent skull roof in lungfish and holost fish. The lower jaw defines a chin.

The simpler structure is found in jawless fish, in which the cranium is normally represented by a trough-like basket of cartilaginous elements only partially enclosing the brain, and associated with the capsules for the inner ears and the single nostril. Distinctively, these fish have no jaws.

Cartilaginous fish, such as sharks and rays, have also simple, and presumably primitive, skull structures. The cranium is a single structure forming a case around the brain, enclosing the lower surface and the sides, but always at least partially open at the top as a large fontanelle. The most anterior part of the cranium includes a forward plate of cartilage, the rostrum, and capsules to enclose the olfactory organs. Behind these are the orbits, and then an additional pair of capsules enclosing the structure of the inner ear. Finally, the skull tapers towards the rear, where the foramen magnum lies immediately above a single condyle, articulating with the first vertebra. There are, in addition, at various points throughout the cranium, smaller foramina for the cranial nerves. The jaws consist of separate hoops of cartilage, almost always distinct from the cranium proper.

In ray-finned fish, there has also been considerable modification from the primitive pattern. The roof of the skull is generally well formed, and although the exact relationship of its bones to those of tetrapods is unclear, they are usually given similar names for convenience. Other elements of the skull, however, may be reduced; there is little cheek region behind the enlarged orbits, and little, if any bone in between them. The upper jaw is often formed largely from the premaxilla, with the maxilla itself located further back, and an additional bone, the symplectic, linking the jaw to the rest of the cranium.

Although the skulls of fossil lobe-finned fish resemble those of the early tetrapods, the same cannot be said of those of the living lungfishes. The skull roof is not fully formed, and consists of multiple, somewhat irregularly shaped bones with no direct relationship to those of tetrapods. The upper jaw is formed from the pterygoids and vomers alone, all of which bear teeth. Much of the skull is formed from cartilage, and its overall structure is reduced.

The skulls of the earliest tetrapods closely resembled those of their ancestors amongst the lobe-finned fishes. The skull roof is formed of a series of plate-like bones, including the maxilla, frontals, parietals, and lacrimals, among others. It is overlaying the endocranium, corresponding to the cartilaginous skull in sharks and rays. The various separate bones that compose the temporal bone of humans are also part of the skull roof series. A further plate composed of four pairs of bones forms the roof of the mouth; these include the vomer and palatine bones. The base of the cranium is formed from a ring of bones surrounding the foramen magnum and a median bone lying further forward; these are homologous with the occipital bone and parts of the sphenoid in mammals. Finally, the lower jaw is composed of multiple bones, only the most anterior of which (the dentary) is homologous with the mammalian mandible.

In living tetrapods, a great many of the original bones have either disappeared or fused into one another in various arrangements.

Birds have a diapsid skull, as in reptiles, with a prelachrymal fossa (present in some reptiles). The skull has a single occipital condyle. The skull consists of five major bones: the frontal (top of head), parietal (back of head), premaxillary and nasal (top beak), and the mandible (bottom beak). The skull of a normal bird usually weighs about 1% of the bird's total bodyweight. The eye occupies a considerable amount of the skull and is surrounded by a sclerotic eye-ring, a ring of tiny bones. This characteristic is also seen in reptiles.

Living amphibians typically have greatly reduced skulls, with many of the bones either absent or wholly or partly replaced by cartilage. In mammals and birds, in particular, modifications of the skull occurred to allow for the expansion of the brain. The fusion between the various bones is especially notable in birds, in which the individual structures may be difficult to identify.

The temporal fenestrae are anatomical features of the skulls of several types of amniotes, characterised by bilaterally symmetrical holes (fenestrae) in the temporal bone. Depending on the lineage of a given animal, two, one, or no pairs of temporal fenestrae may be present, above or below the postorbital and squamosal bones. The upper temporal fenestrae are also known as the supratemporal fenestrae, and the lower temporal fenestrae are also known as the infratemporal fenestrae. The presence and morphology of the temporal fenestra are critical for taxonomic classification of the synapsids, of which mammals are part.

Physiological speculation associates it with a rise in metabolic rates and an increase in jaw musculature. The earlier amniotes of the Carboniferous did not have temporal fenestrae but two more advanced lines did: the synapsids (mammal-like reptiles) and the diapsids (most reptiles and later birds). As time progressed, diapsids' and synapsids' temporal fenestrae became more modified and larger to make stronger bites and more jaw muscles. Dinosaurs, which are diapsids, have large advanced openings, and their descendants, the birds, have temporal fenestrae which have been modified. Mammals, which are synapsids, possess one fenestral opening in the skull, situated to the rear of the orbit.

Classification

There are four types of amniote skull, classified by the number and location of their temporal fenestrae. These are:

Anapsida - no openings

Synapsida - one low opening (beneath the postorbital and squamosal bones)

Euryapsida - one high opening (above the postorbital and squamosal bones); euryapsids actually evolved from a diapsid configuration, losing their lower temporal fenestra.

Diapsida - two openings

Evolutionarily, they are related as follows:

The jugal is a skull bone found in most reptiles, amphibians, and birds. In mammals, the jugal is often called the zygomatic bone or malar bone.

The prefrontal bone is a bone separating the lacrimal and frontal bones in many tetrapod skulls.

This article incorporates text in the public domain from page 128 of the 20th edition of Gray's Anatomy (1918)

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The skull is a bony structure that forms the head in vertebrates. It supports the structures of the face and provides a protective cavity for the brain. The skull is composed of two parts: the cranium and the mandible. In humans, these two parts are the neurocranium and the viscerocranium or facial skeleton that includes the mandible as its largest bone.

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The clavicle, collarbone or keybone, is a slender, S-shaped long bone approximately 6 inches (15 cm) long that serves as a strut between the shoulder blade and the sternum (breastbone). There are two clavicles, one on the left and one on the right. The clavicle is the only long bone in the body that lies horizontally. Together with the shoulder blade, it makes up the shoulder girdle. It is a palpable bone and, in people who have less fat in this region, the location of the bone is clearly visible. It receives its name from Latin clavicula 'little key' because the bone rotates along its axis like a key when the shoulder is abducted. The clavicle is the most commonly fractured bone. It can easily be fractured by impacts to the shoulder from the force of falling on outstretched arms or by a direct hit.

The collarbone is a thin doubly curved long bone that connects the arm to the trunk of the body. Located directly above the first rib, it acts as a strut to keep the scapula in place so that the arm can hang freely. At its rounded medial end (sternal end), it articulates with the manubrium of the sternum (breastbone) at the sternoclavicular joint. At its flattened lateral end (acromial end), it articulates with the acromion, a process of the scapula (shoulder blade), at the acromioclavicular joint.

Right clavicle-from below, and from above

Left clavicle-from above, and from below

The rounded medial region (sternal region) of the shaft has a long curve laterally and anteriorly along two-thirds of the entire shaft. The flattened lateral region (acromial region) of the shaft has an even larger posterior curve to articulate with the acromion of the scapula. The medial region is the longest clavicular region as it takes up two-thirds of the entire shaft. The lateral region is both the widest clavicular region and thinnest clavicular region. The lateral end has a rough inferior surface that bears a ridge, the trapezoid line, and a slight rounded projection, the conoid tubercle (above the coracoid process). These surface features are attachment sites for muscles and ligaments of the shoulder.

It can be divided into three parts: medial end, lateral end, and shaft.

The medial end is also known as the sternal end. It is quadrangular and articulates with the clavicular notch of the manubrium of the sternum to form the sternoclavicular joint. The articular surface extends to the inferior aspect for articulation with the first costal cartilage.

The lateral end is also known as the acromial end. It is flat from above downward. It bears a facet that articulates with the shoulder to form the acromioclavicular joint. The area surrounding the joint gives an attachment to the joint capsule. The anterior border is concave forward and the posterior border is convex backward.

The shaft is divided into two main regions, the medial region, and the lateral region. The medial region is also known as the sternal region, it is the longest clavicular region as it takes up two-thirds of the entire shaft. The lateral region is also known as the acromial region, it is both the widest clavicular region and thinnest clavicular region.

3D model of the clavicle

Lateral region of the shaft

The lateral region of the shaft has two borders and two surfaces.

the anterior border is concave forward and gives origin to the deltoid muscle.

the posterior border is convex and gives attachment to the trapezius muscle.

the inferior surface has a ridge called the trapezoid line and a tubercle; the conoid tubercle for attachment with the trapezoid and the conoid ligament, part of the coracoclavicular ligament that serves to connect the collarbone with the coracoid process of the scapula.

Parts of clavicle

The collarbone is the first bone to begin the process of ossification (laying down of minerals onto a preformed matrix) during development of the embryo, during the fifth and sixth weeks of gestation. However, it is one of the last bones to finish ossification at about 21-25 years of age. Its lateral end is formed by intramembranous ossification while medially it is formed by endochondral ossification. It consists of a mass of cancellous bone surrounded by a compact bone shell. The cancellous bone forms via two ossification centres, one medial and one lateral, which fuse later on. The compact forms as the layer of fascia covering the bone stimulate the ossification of adjacent tissue. The resulting compact bone is known as a periosteal collar.

Even though it is classified as a long bone, the collarbone has no medullary cavity ( marrow cavity) like other long bones. It is made up of spongy cancellous bone with a shell of compact bone. It is a dermal bone derived from elements originally attached to the skull.

The shape of the clavicle varies more than most other long bones. It is occasionally pierced by a branch of the supraclavicular nerve. In males the clavicle is usually longer and larger than in females. A study measuring 748 males and 252 females saw a difference in collarbone length between age groups 18-20 and 21-25 of about 6 and 5 mm (0.24 and 0.20 in) for males and females respectively.

The left clavicle is usually longer and weaker than the right clavicle.

The collarbones are sometimes partly or completely absent in cleidocranial dysostosis.

The levator claviculae muscle, present in 2-3% of people, originates on the transverse processes of the upper cervical vertebrae and is inserted in the lateral half of the clavicle.

The collarbone serves several functions:

It serves as a rigid support from which the scapula and free limb are suspended; an arrangement that keeps the upper limb away from the thorax so that the arm has maximum range of movement. Acting as a flexible, crane-like strut, it allows the scapula to move freely on the thoracic wall.

Relation of Brachial Plexus with the Clavicle

Covering the cervicoaxillary canal, it protects the neurovascular bundle that supplies the upper limb.

Transmits physical impacts from the upper limb to the axial skeleton.

Muscles and ligaments that attach to the collarbone include:

A vertical line drawn from the mid-clavicle called the mid-clavicular line is used as a reference in describing cardiac apex beat during medical examination. It is also useful for evaluating an enlarged liver, and for locating the gallbladder which is between the mid-clavicular line and the transpyloric plane.

Clavicle fractures (colloquially, a broken collarbone) occur as a result of injury or trauma. The most common type of fractures occur when a person falls horizontally on the shoulder or with an outstretched hand. A direct hit to the collarbone will also cause a break. In most cases, the direct hit occurs from the lateral side towards the medial side of the bone. The most common site of fracture is the junction between the two curvatures of the bone, which is the weakest point. This results in the sternocleidomastoid muscle lifting the medial aspect superiorly, which can result in perforation of the overlying skin.

The clavicle first appears as part of the skeleton in primitive bony fish, where it is associated with the pectoral fin; they also have a bone called the cleithrum. In such fish, the paired clavicles run behind and below the gills on each side, and are joined by a solid symphysis on the fish's underside. They are, however, absent in cartilaginous fish and in the vast majority of living bony fish, including all of the teleosts.

The earliest tetrapods retained this arrangement, with the addition of a diamond-shaped interclavicle between the base of the clavicles, although this is not found in living amphibians. The cleithrum disappeared early in the evolution of reptiles, and is not found in any living amniotes, but the interclavicle is present in most modern reptiles, and also in monotremes. In modern forms, however, there are a number of variations from the primitive pattern. For example, crocodilians and salamanders lack clavicles altogether (although crocodilians do retain the interclavicle), while in turtles, they form part of the armoured plastron.

The interclavicle is absent in marsupials and placental mammals. In many mammals, the clavicles are also reduced, or even absent, to allow the scapula greater freedom of motion, which may be useful in fast-running animals.

Though a number of fossil hominin (humans and chimpanzees) clavicles have been found, most of these are mere segments offering limited information on the form and function of the pectoral girdle. One exception is the clavicle of AL 333x6/9 attributed to Australopithecus afarensis which has a well-preserved sternal end. One interpretation of this specimen, based on the orientation of its lateral end and the position of the deltoid attachment area, suggests that this clavicle is distinct from those found in extant apes (including humans), and thus that the shape of the human shoulder dates back to less than 3 to 4 million years ago. However, analyses of the clavicle in extant primates suggest that the low position of the scapula in humans is reflected mostly in the curvature of the medial portion of the clavicle rather than the lateral portion. This part of the bone is similar in A. afarensis and it is thus possible that this species had a high shoulder position similar to that in modern humans.

In dinosaurs the main bones of the pectoral girdle were the scapula (shoulder blade) and the coracoid, both of which directly articulated with the clavicle. The clavicle was present in saurischian dinosaurs but largely absent in ornithischian dinosaurs. The place on the scapula where it articulated with the humerus (upper bone of the forelimb) is the called the glenoid. The clavicles fused in some theropod dinosaurs to form a furcula, which is the equivalent to a wishbone.

In birds, the clavicles and interclavicle have fused to form a single Y-shaped bone, the furcula or "wishbone" which evolved from the clavicles found in coelurosaurian theropods.

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The clavicle, collarbone or keybone, is a slender, S-shaped long bone approximately 6 inches (15 cm) long that serves as a strut between the shoulder blade and the sternum (breastbone). There are two clavicles, one on the left and one on the right. The clavicle is the only long bone in the body that lies horizontally.

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In human anatomy, the wrist is variously defined as (1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand; (2) the wrist joint or radiocarpal joint, the joint between the radius and the carpus and; (3) the anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, bracelet lines, the flexor retinaculum, and the extensor retinaculum.

As a consequence of these various definitions, fractures to the carpal bones are referred to as carpal fractures, while fractures such as distal radius fracture are often considered fractures to the wrist.

The distal radioulnar joint is a pivot joint located between the bones of the forearm, the radius and ulna. Formed by the head of the ulna and the ulnar notch of the radius, this joint is separated from the radiocarpal joint by an articular disk lying between the radius and the styloid process of the ulna. The capsule of the joint is lax and extends from the inferior sacciform recess to the ulnar shaft. Together with the proximal radioulnar joint, the distal radioulnar joint permits pronation and supination.

The radiocarpal joint or wrist joint is an ellipsoid joint formed by the radius and the articular disc proximally and the proximal row of carpal bones distally. The carpal bones on the ulnar side only make intermittent contact with the proximal side - the triquetrum only makes contact during ulnar abduction. The capsule, lax and un-branched, is thin on the dorsal side and can contain synovial folds. The capsule is continuous with the midcarpal joint and strengthened by numerous ligaments, including the palmar and dorsal radiocarpal ligaments, and the ulnar and radial collateral ligaments.

The parts forming the radiocarpal joint are the lower end of the radius and under surface of the articular disk above; and the scaphoid, lunate, and triquetral bones below. The articular surface of the radius and the undersurface of the articular disk form together with a transversely elliptical concave surface, the receiving cavity. The superior articular surfaces of the scaphoid, lunate, and triquetrum form a smooth convex surface, the condyle, which is received into the concavity.

Carpal bones of the hand:

In the hand proper a total of 13 bones form part of the wrist: eight carpal bones- scaphoid, lunate, triquetral, pisiform, trapezium, trapezoid, capitate, and hamate- and five metacarpal bones-the first, second, third, fourth, and fifth metacarpal bones.

The midcarpal joint is the S-shaped joint space separating the proximal and distal rows of carpal bones. The intercarpal joints, between the bones of each row, are strengthened by the radiate carpal and pisohamate ligaments and the palmar, interosseous, and dorsal intercarpal ligaments. Some degree of mobility is possible between the bones of the proximal row while the bones of the distal row are connected to each other and to the metacarpal bones -at the carpometacarpal joints- by strong ligaments -the pisometacarpal and palmar and dorsal carpometacarpal ligament- that makes a functional entity of these bones. Additionally, the joints between the bases of the metacarpal bones -the intermetacarpal articulations- are strengthened by dorsal, interosseous, and palmar intermetacarpal ligaments.

The earliest carpal bones to ossify are capitate bone and hamate bone in the first six months of an infant life.

Articulations

The radiocarpal, intercarpal, midcarpal, carpometacarpal, and intermetacarpal joints often intercommunicate through a common synovial cavity.

Articular Surfaces

It has two articular surfaces named, proximal and distal articular surfaces respectively. The proximal articular surface is made up of the lower end of the radius and a triangular articular disc of the inferior radio-ulnar joint. On the other hand, the distal articular surface is made up of proximal surfaces of the scaphoid, triquetral and lunate bones.

Micro-radiography of 8-weeks human embryo hand

The extrinsic hand muscles are located in the forearm where their bellies form the proximal fleshy roundness. When contracted, most of the tendons of these muscles are prevented from standing up like taut bowstrings around the wrist by passing under the flexor retinaculum on the palmar side and the extensor retinaculum on the dorsal side. On the palmar side the carpal bones form the carpal tunnel, through which some of the flexor tendons pass in tendon sheaths that enable them to slide back and forth through the narrow passageway (see carpal tunnel syndrome).

Starting from the mid-position of the hand, the movements permitted in the wrist proper are (muscles in order of importance):

Magnetic resonance imaging (MRI) of radial abduction (rightwards in image) and ulnar adduction (leftwards in image)

Marginal movements: radial deviation (abduction, movement towards the thumb) and ulnar deviation (adduction, movement towards the little finger). These movements take place about a dorsopalmar axis (back to front) at the radiocarpal and midcarpal joints passing through the capitate bone.

Movements in the plane of the hand: flexion (palmar flexion, tilting towards the palm) and extension (dorsiflexion, tilting towards the back of the hand). These movements take place through a transverse axis passing through the capitate bone. Palmar flexion is the most powerful of these movements because the flexors, especially the finger flexors, are considerably stronger than the extensors.

Magnetic resonance imaging (MRI) of wrist extension and return to neutral position

Extension (up to 60°): extensor digitorum, extensor carpi radialis longus, extensor carpi radialis brevis, extensor indicis, extensor pollicis longus, extensor digiti minimi, extensor carpi ulnaris

Palmar flexion (up to 70°): flexor digitorum superficialis, flexor digitorum profundus, flexor carpi ulnaris, flexor pollicis longus, flexor carpi radialis, abductor pollicis longus

Intermediate or combined movements

However, movements at the wrist can not be properly described without including movements in the distal radioulnar joint in which the rotary actions of supination and pronation occur and this joint is therefore normally regarded as part of the wrist.

Projectional radiograph of a normal wrist (left image) and one with a dorsal tilt due to wrist osteoarthritis (as well as osteoporosis). The angle of the distal surface of the lunate bone is annotated. A dorsal tilt of 10 to 15 degrees is considered normal.[18]

Wrist pain has a number of causes, including carpal tunnel syndrome, ganglion cyst, tendinitis, and osteoarthritis. Tests such as Phalen's test involve palmarflexion at the wrist.

The hand may deviate at the wrist in some conditions, such as rheumatoid arthritis.

Ossification of the bones around the wrist is one indicator used in taking a bone age.

A wrist fracture usually means a fracture of the distal radius.

The English word " wrist" is etymologically derived from the Proto-Germanic word wristiz from which are derived modern German (" instep", "wrist") and modern Swedish ("instep", " ankle"). The base writh- and its variants are associated with Old English words " wreath", " wrest", and " writhe". The wr- sound of this base seems originally to have been symbolic of the action of twisting.

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In human anatomy, the wrist is variously defined as (1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand; (2) the wrist joint or radiocarpal joint, the joint between the radius and the carpus and; (3) the anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints.

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2. axial skeleton- forms the main trunk of the body and is composed of the skull 

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2. axial skeleton- forms the main trunk of the body and is composed of the skull 

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1. appendicular skeleton- forms the extremities and is composed of the should griddle, arm bones, pelvic griddle and leg bones  

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1. appendicular skeleton- forms the extremities and is composed of the should griddle, arm bones, pelvic griddle and leg bones  

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The appendicular skeleton is the portion of the skeleton of vertebrates consisting of the bones that support the appendages. There are 126 bones. The appendicular skeleton includes the skeletal elements within the limbs, as well as supporting shoulder girdle pectoral and pelvic girdle. The word appendicular is the adjective of the noun appendage, which itself means a part that is joined to something larger.

Of the 206 bones in the human skeleton, the appendicular skeleton comprises 126. Functionally it is involved in locomotion (lower limbs) of the axial skeleton and manipulation of objects in the environment (upper limbs).

The appendicular skeleton forms during development from cartilage, by the process of endochondral ossification.

The appendicular skeleton is divided into six major regions:

1. Shoulder girdles (4 bones) - Left and right clavicle (2) and scapula (2).

2. Arms and forearms (6 bones) - Left and right humerus (2) (arm), ulna (2) and radius (2) (forearm).

3. Hands (54 bones) - Left and right carpals (16) (wrist), metacarpals (10), proximal phalanges (10), intermediate phalanges (8) and distal phalanges (10).

4. Pelvis (2 bones) - left hip bone and right hip bone (2).

5. Thighs and legs (8 bones) - Left and right femur (2) (thigh), patella (2) (knee), tibia (2) and fibula (2) (leg).

6. Feet and ankles (52 bones) - Left and right tarsals (14) (ankle), metatarsals (10), proximal phalanges (10), intermediate phalanges (8) and distal phalanges (10).

It is important to realize that through anatomical variation it is common for the skeleton to have many accessory bones ( sutural bones in the skull, cervical ribs, lumbar ribs and even extra lumbar vertebrae).

The appendicular skeleton of 126 bones and the axial skeleton of 80 bones together form the complete skeleton of 206 bones in the human body. Unlike the axial skeleton, the appendicular skeleton is unfused. This allows for a much greater range of motion.

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The appendicular skeleton is the portion of the skeleton of vertebrates consisting of the bones that support the appendages. There are 126 bones. The appendicular skeleton includes the skeletal elements within the limbs, as well as supporting shoulder girdle pectoral and pelvic girdle.