# data[].attributes.body
Small Molecules
1.A low molecular weight (<900 daltons) organic compound that may regulate a biological process
2.With a size on the order of 1nm.
3.Metabolomics focuses on small molecules
4.Metabolomic masses ranging from 50 to 1500 Dalton's

# data[].attributes.body
Small molecules in human disease treatment

Can be allosteric modifiers in the cystol, nuclei and central nervous system due to their small size and normal physiochemical properties.

Can target extracellular proteins or intracellular receptors.

Can precisely regulate target functions in complex biological systems in a dose- and time-dependent manner.

# data[].attributes.body
Small molecules in human disease treatment

Due to small size they are quickly ingested through the gastrointestinal tract

Small size allows them to easily penetrate cell membranes as they travel through the body.

Can be effective enzyme inhibitors

# data[].attributes.body
Small molecules in human disease treatment:

Dominated in past

Have been found to play an increasingly important role in the development of new medicines to treat a variety of human disease nowadays

Used to increase the productivity of new drug production.

# data[].attributes.body
Examples of Small Molecule

Sugars

Lipids

Amino Acids

Fatty Acids

Alkaloids etc.

# data[].attributes.body
Alkaloids(a.Morphine &b.Atropine)

# data[].attributes.body
Lipids

# data[].attributes.body
Sugar (Sucrose)

# data[].attributes.body
Majority of new drugs and therapeutics starting to grasp the technological advancement of small-molecules. As the days are advancing towards better science and technology, biologists, chemists and all the drug experts are relying on the best usage of small-molecule drugs and therapies. While the immediate-release dosage forms dominate the market today, more specialized and rationalized products incorporating the concepts of drug delivery are being developed to overcome the physicochemical, physiological and pharmacological challenges inherent with the drugs, and to improve the treatment regimens for the patients.

# data[].attributes.body
Factors to consider in case of small-molecule drug:

1. Small-molecule drugs are nearly always taken as pills. This can give them an edge over larger drugs that require injections.

2. Their size and relative simplicity leave them more exposed to generic competition than larger, complex biologic drugs.

3. A common small molecule drug is acetylsalicylic acid, the active ingredient of Aspirin. In contrast, large molecules, known as biologics or therapeutic proteins, often have to be administered by injection.

4. The hero to fight psoriasis Otezla, a small-molecular drug earned its company almost a billion through all the competitions.

# data[].attributes.body
i)  Small molecules can go inside the cell.

ii)  Chemically synthesized in lab.

iii)  Much stable

iv)  Small molecule in cancer treatment
v) Can influenced enzyme, neuron, hormone.

# data[].attributes.body
i) Needs longer time for research.
ii) Have to spend a lot of money

# data[].attributes.body
Small molecule drugs development program often presents us unique challenges. Medicinal chemistry always help us to overcome those challenges .By developing our skills small molecule drugs can help maximize our success. We should research more and develop this technology for better life saving movements in future.