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David Vetter, known as the 'boy in the bubble', lived in a sterile isolator to keep him alive and germ-free until a bone marrow transplant could be performed. In this image Dr. William Shearer and Dr. Mary Murphy are preparing David for his bone marrow transplant.

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1985 - Identifying genes

Rapid identification of genes for immune cells, antibodies, cytokines and other immunological structures begins.

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a blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.

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Black death/Plague doctor

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A blood protein produced in response to and counteracting a specific antigen, antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.

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The standard vaccine for smallpox is stopped because it is considered that the risk of the vaccination for serious complications is greater than the risk for the reintroduction of smallpox in 1972

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430 BC - Early natural immunity noted

General Thucydides notes the appearance of natural immunity in victims of a plague in Athens stating, “No one was ever attacked a second time.”

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Pasteurisation and vaccines

Biologist and chemist Louis Pasteur becomes aware of the presence of germs and is responsible for the process of pasteurisation.

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1000 AD - The Chinese vaccinate people against smallpox.

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Thucydides observes that people develop immunity to diseases after exposure.

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In 1000 A.D The Chinese inoculate people against smallpox with material squeezed from smallpox pustules.