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In 1967, Marburg virus was first discovered when outbreaks of the Hemorrhagic fever occurred simultaneously in laboratories in Germany and in Yugoslavia.

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There have been many different origins of the Marburg virus. They consist of:
- The first case was reported when imported African green monkeys transmitted the disease to lab scientists while they were conducting research.
- The more crucial host of the Marburg virus is the African fruit bat (They do not show signs of illness)

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- After roughly 5-10 days, symptoms appear
- Fever, chills, headache, myalgia are common symptoms
- Rashes (Most prominent in the trunk), nausea, chest pain, sore throat, abdominal pain, and diarrhea are symptoms that MAY occur

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Diagnosis of the disease is difficult because Marburg works similarly to malaria or typhoid fever. This is especially apparent when only one case is involved.
- If symptoms are found early, the patient should be isolated and public health professionals should be notified
- Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing, polymerase chain reaction (PCR), and IgM-capture ELISA are all able to be used to confirm a case of Marburg within a few days of symptoms
- Virus isolation may be preformed but should only take place in a high containment laboratory with good practices

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Animal -> Human
It is unknown how the disease first transmitted from its original animal hosts to humans, but contact with infected bat feces or aerosols are most likely the root of the infections; however, this is only a possibility.

Human -> Human
Transmission from a human to another human can occur in several ways: direct contact to infected person’s body fluid or contact with equipment and other objects infected with a patient’s blood or tissues.

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Measures needed to prevent Marburg virus aren’t known very well for wildlife to human transmission; however, avoiding sick animals in central Africa and fruit bats are a good way to prevent against infection.  Also, preventing direct physical contact with patients infected with Marburg is another way to prevent infection.

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No specific treatment exists for the Marburg hemorrhagic fever. Experimental treatments have happened in non-human primates, but never on humans.

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The first infected population were the small outbreaks in Germany and Serbia when the infection was first discovered.

Sporadic cases of Marburg have been reported in Angola, Democratic Republic, Kenya and South Africa.

Uganda has been the most recent affected population when two independent cases were reported by travelers in 2008.

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1967-2014
464 Incidents of Marburg virus have been identified in all of history. No recent incidents have occurred since 2014, in Uganda. Roughly 80% of humans infected have died.

Notable outbreaks were the Republic of Congo in 2000 when 252 people were infected, and in Angola in 2004 when 252 people were infected.

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Most cases have been centered around central Africa. Europe has had quite a few cases, while the United States has had an isolated report of Marburg.

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- All age groups are susceptible to infection, but most cases have occurred in adults
- How an animal can transmit the infection to a human is still unknown
- The case-fatality rate is currently unknown, however most estimates range from 22-88% (CDC reports an 88% fatality rate)
- The Ebola and Marburg virus are extremely similar in how they work; however, the transmission from its original primates is different
- No cases, luckily, have been reported since 2014