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https://www.chop.edu/stories/trisomy-21-down-syndrome-jennas-story

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Type:Chromosomal based
Gene:Chromosome 21

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Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone in infancy.Individuals with Down syndrome have an increased risk of developing several medical conditions like gastroesophageal reflux,thyroid gland,leukemia,and hearing and vision problems.Children with down syndrome are reported to have delayed development behavior problems.Also adults with down syndrome have an increased risk of developing Alzheimer's disease which causes memory loss but mostly it develops when the adults are  in their fifties and sixties.

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Most causes of down Syndrome are trisomy 21 which means each cell in the body has three copies of chromosome 21 instead of the usual two copies. Rarely this happens when down syndrome occurs when a part of chromosome 2 comes together as one chromosome during the formation of the cells. Another rare cause is another copy of chromosome 21 in only some body cells. -Mateo

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Down syndrome occurs in 1 in 800 newborns.200,000 people in the country have a related case of down syndrome.

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Down syndrome is often not inherited to the children of one person who is diagnosed with down syndrome.An error in cell division creates another copy of the chromosome.