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The start of the Beaver Wars, which took place between the French, Iroquois Confederacy, and other nations such as the Erie and Ojibwe.

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Robert de la Salle leaves on an expedition with a few dozen men to explore the Great Lakes.

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Hudson’s Bay Company is founded in Canada, which expanded British trade in the Americas.

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Europeans begin using the Ohio River for trade.

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French declares the Ohio River Valley for France.

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Alliquippa spots the first Europeans traveling with other Native Americans

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The French controlled the fur trade.

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Ojibwe, Ottawa allies, and French troops, raid the Miami village and British trading post of Pickawillany, killing 14.

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The Start of the French and Indian War

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The Battle of Jumonville Glen is fought. It is won by the British in 15 minutes against the French and is where Tanaghrisson — the Seneca leader — attacks the French commander once they surrendered.

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The signing of the Treaty of Paris, ending the French and Indian War.

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King George III establishes the Proclamation of 1763, declaring Europeans from settling on lands west of the Appalachian Mountains. It also recognized that Native Americans have a right to the land they lived on.

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The Seneca, Wyandot, Potawatomi, and Miami American Indians begin to capture British forts, including Fort Miami and Fort Sandusky. This starts Pontiac’s War.

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The American Indians sign a treaty, ending Pontiac’s War in a stalemate.

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The Boston Massacre occurs, a key event leading to the American Revolution.