# data[].attributes.body
- Content from unit 2 lectures folder in Blackboard (https://acconline.austincc.edu/webapps/blackboard/content/listContent.jsp?course_id=_872130_1&content_id=_20641650_1)
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1159308/

# data[].attributes.body
- Receptors: Beta-1 and Beta-2 (blocks both receptors)
- Action: Decreases force of contraction, decreases cardiac output, decreases HR, decreases conduction and cardiac output and blood pressure, bronchoconstriction.
- Drugs: timolol (Blocadren®), propanolol (Inderal®) nadolol (Corgard®)

# data[].attributes.body
- Receptor: Beta 1 (blocks this receptor)
- Action: Decreases force of contraction and cardiac output, decreases heart rate, decreases conduction, and decreases blood pressure
- Drugs: metoprolol (Lopressor®), atenolol (Tenormin®)

# data[].attributes.body
- Receptors: beta 2 receptors are stimulated
- Actions: Relaxation of smooth muscles in lungs and leads to bronchodilation, and relaxation of smooth muscle of the uterus
- Drugs: salmeterol (Serevent®), formoterol (Foradil®), terbutaline (Brethine®), albuterol (Proventil®, Ventolin®)

# data[].attributes.body
- Receptors: d-1 receptors in kidneys, beta 1 receptors in heart, or alpha 1 receptors
- Action: Vasodilation and increased renal blood flow (low dose), increases cardiac output and force of contraction in heart (moderate dose), increases blood pressure (high dose)
- Drugs: dobutamine

# data[].attributes.body
- Receptors: Alpha 1 (binds and blocks these receptors)
- Action: Relaxation of smooth muscle, vasodilation, decreases blood pressure, relaxes smooth muscles of ureters and increases urine flow
- Drugs: doxazosin (Cardura®), terazosin (Hytrin®), prazosin (Minipress®)

# data[].attributes.body
- Receptor: Stimulates alpha and beta receptors.
- Action: Vasoconstriction and increases blood pressure. Bronchodilator, cardiac stimulant.
- Drugs: epinephrine (Adrenalin®)

# data[].attributes.body
- Receptor: Alpha 1 receptor is stimulated
- Action: Contraction of smooth muscled, increased blood pressure, vasoconstriction of nasal passages, constriction of blood vessels. Can act as a decongestant.
- Drugs: ephedrine, phenylephrine (Neo-Synephrine®)

# data[].attributes.body
- Receptors: Binds to cholinergic receptor
- Action: Blocking drug. Increases HR, decreases GI secretions, bronchodilation, mydriasis, slows digestion, decreases GI secretions and motility.
- Drugs: atropine, ipratropium bromide (Atrovent®), dicyclomine (Bentyl®)

# data[].attributes.body
-Receptors: Nm receptors
-Actions: Inhibits acetylcholinesterase and increases ACH
-Drugs: neostigmine (Prostigmin®)

# data[].attributes.body
- Receptors: Muscarinic
-Action: Mimics ACH
- Drugs: ACH, bethanechol (Urecholine®), pilocarpine (Pilocar®)

# data[].attributes.body
- Direct Acting Cholinergic Agonist
- Indirect Acting Cholinergic Agonist
- Anticholinergic

# data[].attributes.body
- Alpha 1 Adrenergic Agonists
- Adrenergic Agonists
- Alpha 1 Adrenergic Blocking Drugs
- Beta Adrenergic Agonists
- Beta Adrenergic Blocking drugs (includes selective and non-selective beta blockers)

# data[].attributes.headline
End organ responses of each transmitter:

# data[].attributes.subject
End organ responses of each transmitter:

# data[].attributes.body
- Muscarinic: Decreases heart rate, bronchoconstriction, increases digestion, increases GI movement and secretions, increases urination, and leads to pupil constriction.
- Nicotinic 1 (Nn): Depolarization
- Nicotinic 2 (Nm): Skeletal muscle contracts when stimulated.

# data[].attributes.headline
End organ responses of each transmitter:

# data[].attributes.subject
End organ responses of each transmitter:

# data[].attributes.body
- Alpha 1: Stimulated by EPI and NE. Smooth muscle contraction which leads to an increase in blood pressure.
- Alpha 2: Decreases contraction of smooth muscle which leads to vasodilation and decreased blood pressure.
- Beta 1: Increases force of contraction, increases heart rate, increases conduction. Stimulated by NE and EPI.
- Beta 2: Leads to smooth muscle relaxation, bronchodilation, uterine relaxation and coronary arteries and skeletal muscle relaxation. Vasodilation. Stimulated by EPI.

# data[].attributes.body
- Muscarinic: Smooth muscle, cardiac, glands at parasympathetic postganglionic nerve endings.
- Nicotinic 1 (Nn): Synapse area. (Ganglia of parasympathetic nerves and sympathetic nerves).
- Nicotinic 2 (Nm): Neuromuscular junction of skeletal muscle

# data[].attributes.body
- Muscarinic
- Nicotinic 1 (Nn)
- Nicotinic 2 (Nm)

# data[].attributes.body
- Alpha 1: Glands, smooth muscles, eyes, arteries, veins
- Alpha 2: Pre & post synaptic neurons
- Beta 1: Heart
- Beta 2: Smooth muscle, lungs, uterus, skeletal muscle arteries, coronary arteries

# data[].attributes.body
- Alpha 1
- Alpha 2
- Beta 1
- Beta 2

# data[].attributes.headline
Location where each neurotransmitter is released:

# data[].attributes.subject
Location where each neurotransmitter is released:

# data[].attributes.body
- Acetylcholine (ACH): Released at ganglia from presynaptic nerve endings
- Norepinephrine (NE): Released at postganglionic nerve endings.
- Epinephrine (EPI): Medulla of adrenal glands
- Dopamine (DA): hypothalamus

# data[].attributes.headline
Locations where each neurotransmitter is released:

# data[].attributes.subject
Locations where each neurotransmitter is released:

# data[].attributes.body
- ACH is released at ganglia and postganglionic nerve endings

# data[].attributes.body
- Acetylcholine (ACH)

# data[].attributes.body
- Acetylcholine (ACH)
- Norepinephrine (NE)
- Epinephrine (EPI)
- Dopamine (DA)