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Work Cited "Famous People with Tay Sachs Disease - HRF." HRF. N.p., 16 Jan. 2014. Web. 18 Feb. 2015. "Learning About Tay-Sachs Disease." Learning About Tay-Sachs Disease. N.p., n.d. Web. 17 Feb. 2015. "Meet Gavin." YouTube. YouTube, n.d. Web. 18 Feb. 2015. "Nathan's Story; Tay-Sachs Disease in the Irish Population."

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Tay-Sachs is a very rare disease usually found in the Ashkenazi Jewish people. The disorder happens in chromosome 15 where there is a slight misspelling of the 4 letter alphabet used in chromosomes.

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Uploaded by Carolina Gamino on 2015-04-01.

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Video made for Biology class on genetic disorders. enjoy!

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www.encyclopedia.com/medicine/diseases-and-condition/pathology/tay-sachs-disease
www.healthline.com/health/tay-sachs-disease#risk-factors4
medlineplus.gov/ency/article/001417.htm

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Chances of Giving the Disease to Your Child

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Chances of Giving the Disease to Your Child

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The chances of your child having Tay- Sachs is very very low. It is even low for people of Ashkenazi Jewish descent, but higher than for people who are not Ashkenazai Jews. A child getting Tay- Sachs disease is like the odds of winning the lottery.

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online:
http://www.mdjunction.com/tay-sachs-disease
https://www.ntsad.org/
other:
National Tay-Sachs & Allied Diseases
phone (617)-277-4463

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This disease was discovered by a man in 1881 named Warren Tay. He was a British Ophthalmologist. This disease was seen by a "cherry red spot"in the retina of a one year old. Then later in 1896 a man named Bernard Sachs observed extreme swelling of neurons in autopsy tissue from the affected child. Then the disease was published and named Tay-Sachs disease.

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There is no cure for Tay-Sachs. Family members with a child who has Tay-Sachs are recommended to spend time with the child. Families are encouraged to join support groups. It is recommended to hang out with your child and show them love.

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The effects on the family are substantial. As a parent of a child with Tay-Sachs you have to always be with them. Meaning your other children may not get a lot of attention or you may not be able to work. As a family you also miss out on family things like camping or traveling. Also due to the outcome of Tay-Sachs, a family could be very sad on the death of there child.

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Symptoms:
deafness
progressive blindness
decreased muscular strength
increased startle response
loss of muscle function
seizure
muscular stiffness
delayed mental and social development
slow growth
red spot on macula
Diagnosis and Treatment Management:
chorionic villus sampling(cvs) done from 10 to 12 weeks of pregnancy
amniocentesis, done from week 15 through 20 of the pregnancy to help the child survive.

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Tay-Sachs disease happens when the body lacks hexosaminidase A. This protein helps break down a group of fat called ganglisides. When this protien dosesn't work excess fat builds up in the brain, nerves, and brain tissue. This is dangerous because the fat keeps the brain from growing and eventually the brain dies causing the child to die.