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Yellow fever is caused by yellow fever virus, an enveloped RNA virus, family Flaviviridae. It infects, amongst others cells, monocytes, macrophages, Schwann cells, and dendritic cells.

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Only  A. aegypti is involved. It is well adapted to urban areas, and can also transmit other diseases, including Zika fever, dengue fever, and chikungunya. The urban cycle is responsible for the major outbreaks of yellow fever that occur in Africa. Except for an outbreak in Bolivia in 1999, this urban cycle no longer exists in South America.

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Aedes africanus (in Africa) or mosquitoes of the genus Haemagogus and Sabethes (in South America) serve as vectors.
The mosquitoes infect mainly  primates; the disease is mostly asymptomatic in African primates.
In South America, the sylvatic cycle is currently the only way humans can become infected, which explains the low incidence of yellow fever cases on the continent.People who become infected in the jungle can carry the virus to urban areas, where A. aegypti acts as a vector.

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Areas with Risk of Yellow Fever Virus Transmission in Africa

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Areas with Risk of Yellow Fever Virus Transmission in South America.

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Areas with Risk of Yellow Fever Virus Transmission in South America.

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Fever.

Headache.

Muscle aches, particularly in your back and knees.

Sensitivity to light.

Nausea, vomiting or both.

Loss of appetite.

Dizziness.

Red eyes, face or tongue.

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Treatment

No specific antiviral treatment for the Zika virus exists. Treatment is aimed at relieving symptoms with rest, fluids and medications — such as acetaminophen

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Get plenty of rest.
Drink fluids to prevent dehydration.

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Do not take aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS)

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After transmission from a mosquito, the viruses replicate in the lymph nodes and infect dendritic cells in particular. From there, they reach the liver and infect hepatocytes (probably indirectly via Kupffer cells), which leads to eosinophilic degradation of these cells and to the release of cytokines. Apoptotic masses known as Councilman bodies appear in the cytoplasm of hepatocytes.

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It is mainly transmitted through the bite of the yellow fever mosquito Aedes aegypti, but other mostly Aedes mosquitoes such as the tiger mosquito (Aedes albopictus) can also serve as a vector for this virus.

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Clean the sick person’s environment daily using household cleaners according to label instructions.

Immediately clean surfaces that have blood or other body fluids on them using household cleaners and disinfectants according to label instructions.

If you live or travel to risk areas take the inmunization or vaccine.

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ver is caused by yellow fever virus, an enveloped RNA virus, family Flaviviridae. It infects, amongst others cells, monocytes, macrophages, Schwann cells, and dendritic cells. 