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Celebrex is a commonly prescribed drug sold by the pharmaceutical company, Pfizer, that is used to relieve pain and inflammation caused by Rheumatoid Arthritis, Osteoarthritis, injuries, and surgeries. Celebrex is a specific type of non-steroidal anti-inflammatory drug (NSAID). Other commonly used NSAIDs are aspirin, ibuprofen, and naproxen to name  a few. Celebrex is specifically a COX-2 inhibitor, which blocks the enzyme in the body that makes prostaglandins: an enzyme that commonly causes pain and swelling.

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Scientific name: Celecoxib
Street name: n/a
Classification: NSAID - COX-2 inhibitor

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Taken orally in the form of a pill with dosages of 50 mg, 100 mg, 200 mg, and 400 mg, Celebrex can show effects within 2-3 weeks.

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Increased risk of heart attacks or strokes

Increased risk of bleeding, ulcers, and tears of the esophagus, stomach, and intestines

Potentially serious side-effects such as high blood pressure, heart failure, liver problems and liver failure, kidney problems and kidney failure, low red blood cells (anemia), and life-threatening skin reactions

Other side effects such as stomach pain, constipation, diarrhea, indigestion, heartburn, nausea, vomiting, and dizziness

Can cause medical emergencies with symptoms of shortness of breath or trouble breathing, chest pain, weakness in one part or side of the body, slurred speech, swelling of the face or throat, skin rashes, or blisters with fever

Serious interactions with alcohol

Allergic reactions causing asthma attacks and or hives

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“Celebrex Information.” Johns Hopkins Arthritis Center, www.hopkinsarthritis.org/patient-corner/drug-information/celecoxib-celebrex/.

“Celebrex Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing.” WebMD, WebMD, www.webmd.com/drugs/2/drug-16849/celebrex-oral/details.

“Move Forward with Brand-Name CELEBREX.” Arthritis Treatment | CELEBREX® (Celecoxib) Capsules | Safety, Pfizer, www.celebrex.com/.

Ogbru, Omudhome. “Celebrex (Celecoxib, ) Side Effects (Alcohol), Dosage, Contraindications.” MedicineNet, www.medicinenet.com/celecoxib/article.htm.

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Celecoxib was developed by G. D Searle & Company and co-promoted under the name Cerebrex by Pfizer, which eventually gained total control of the product

In 1998, Celebrex received approval for use in rheumatoid arthritis and osteoarthritis by the Food and Drugs Administration (FDA) with the added notion that Celebrex carried the risk of heart disease and blood vessel complications.

In 1999, the FDA added a warning that Celebrex could potentially cause serious side effects such as severe bleeding or even death.

In 2006, Celebrex gained approval to treat juvenile rheumatoid arthritis.

Today, patients with JIA can not use Celebrex until they failed under the use of two other commonly prescribed NSAIDs (in my case Naproxen 500 and Mobic).

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Although Celebrex is typically sold to older patients, all teenagers can potentially be prescribed an NSAID for a multitude of reasons. The most common use is one that I deal with, along with every 1 in 1,000 teenagers, called Juvenile Idiopathic Arthritis (JIA). JIA is an autoimmune inflammatory joint disease in children less than 16 years of age. The classification switches to Rheumatoid Arthritis for teenagers 16 years or above, which Celebrex is also commonly prescribed for. Additionally, Celebrex is continuously being studied, and many experts see it as a safer alternative to other NSAIDs, so we may begin to see it in use more and more as we transition to adulthood.