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H1N1 Influenza

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Variola Virus

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SARS-CoV

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Academics agree that the end of the pandemic occurred in 1920, when society ended up developing a collective immunity to the Spanish flu, although the virus never completely disappeared.

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RNA

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ball with spikes around it

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yes

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lung cells

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glycoproteins and glycolipids

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RNA translated to protein

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RNA-dependent RNA polymerase that replicates the RNA genome to make more RNA to put into viral capsids

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Spanish Flu comes from wild birds

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no

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DNA virus

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Vaccine

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no

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Variola virus is a large, brick shaped virus

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Yes

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macrophages and endothelial cells

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Smallpox is spread when a person breathes it in… and out. The virus gets inside the cells lining the throat and hijacks the cellular machinery to make millions more smallpox viruses.

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The virus uses the host cell's RNA polymerase to transcribe and the ribosomes to translate

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DNA replication

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There are no known animal infections

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RNA

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It is circular and covered with spike proteins

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Yes

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It mainly targets the epithelial cells in the respiratory tract of animals and humans

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SARS spreads by airborne droplets, skin to skin contact, saliva, and touching a contaminated surface. Once in the body, the virus binds to the outside of the cell, enters the interior of the cell, then it uses the cellular machinery to make copies of itself and spread to other cells.

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RNA translated to protein

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RNA replication

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yes - bats

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no

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SARS was quickly contained with safety measures. These included isolating Sars patients and quarantining people who had been exposed to the virus. After four months, there were no more cases to be seen.
Mutation