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Tammie Petersen ANS lecture powerpoint

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- acetylcholine: used for miosis

- pilocarpine (Pilocar®)
- bethanechol (Urecholine®)

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- neostigmine (Prostigmin®)

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- atropine: antidote for cholinergic poisoning
- dicyclomine (Bentyl®)
- ipratropium bromide (Atrovent®)

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- bind to a cholinergic receptor
- dry mouth, visual disturbances, urinary retention

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- inhibit acetylcholinesterase
- increases ACH

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- directly stimulate/bind to the muscarinic receptors
- mimics ACH

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response: bronchoconstriction

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response: increased bladder activity such as urination

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response: miosis, pupils constrict

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response: decreased conduction and BP rate and slight decrease in contractility

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- nadolol (Corgard®)
- propanolol (Inderal®)
- timolol (Blocadren®)

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- atenolol (Tenormin®)
- metoprolol (Lopressor®)

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- albuterol (Proventil®, Ventolin®)
- terbutaline (Brethine®)
- formoterol (Foradil®)
- salmeterol (Serevent®)

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- dobutamine

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- prazosin (Minipress®)
- terazosin (Hytrin®)
- doxazosin (Cardura®)

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- epinephrine (Adrenalin®

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- ephedrine
- phenylephrine (Neo-Synephrine®)

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- interacts with beta-1 and beta-2 receptors

- decreases contraction
- decrease conduction

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- interacts with beta-1 receptor
- decreases contraction
- decrease conduction

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- interacts with beta 2 receptors
- bronchodilation

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- low dose: stimulates dopaminergic receptors

- moderate dose: stimulates  beta 1 receptors

- high dose: stimulates alpha-1 receptors

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- interacts with alpha-1 receptors and blocks them
- vasodilation of blood vessels, decreases BP

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- interacts with all alpha and beta receptors
- vasoconstriction, increases BP,  cardiac stimulant, and bronchodilator

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- interacts with alpha-1 receptor
- vasoconstriction

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response: bladder relaxes and activity decreases

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response: hydriasis

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response: bronchodialtion

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response: increased conduction, contractility, and BP rate

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response: vasoconstriction

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located in the neuromuscular junction

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located at ganglia of parasympathetic and sympathetic nerves

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located on cardiac, smooth muscle, and glands

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located in the brain and in the periphery

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located on smooth muscle, lungs, uterus, skeletal muscle arteries, and coronary arteries

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released by the hypothalamus

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located at ganglia

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located on the heart

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located on glands, smooth muscles, eyes, most arteries and veins

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released at ganglia

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located at medulla of the adrenal glands

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located at postganglionic nerve endings

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- rest and digest
- cholinergic
- stimulates one specific body part or system

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- "fight, fright, flight"
- adrenergic
- regulates activity of internal organs and glands during physical and mental stressful situations