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Type: chromosomal condition
Gene chromosomal affected: trisomy 21

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Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate.

People with Down syndrome may have a variety of birth defects. About half of all affected children are born with a heart defect. Digestive abnormalities, such as a blockage of the intestine, are less common.

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Down syndrome occurs in about 1 in 800 newborns. About 5,300 babies with Down syndrome are born in the United States each year, and approximately 200,000 people in this country have the condition. Although women of any age can have a child with Down syndrome, the chance of having a child with this condition increases as a woman gets older.

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  CAUSES                                               down syndrome is a cause of trisomy 21 which is when a chromosome 21 gets attached to another during the formation of reproductive cells.another cause is when someone has another copy of chromosome 21 this is called mosaic.  

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  CAUSES                                               down syndrome is a cause of trisomy 21 which is when a chromosome 21 gets attached to another during the formation of reproductive cells.another cause is when someone has another copy of chromosome 21 this is called mosaic.  

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People with translocation Down syndrome can inherit the condition from an unaffected parent. The parent carries a rearrangement of genetic material between chromosome 21 and another chromosome. This rearrangement is called a balanced translocation. No genetic material is gained or lost in a balanced translocation, so these chromosomal changes usually do not cause any health problems. However, as this translocation is passed to the next generation, it can become unbalanced. People who inherit an unbalanced translocation involving chromosome 21may have extra genetic material from chromosome 21, which causes Down syndrome.

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MedlinePlus Genetics provides information about the effects of genetic variation on human health. Learn about genetic conditions, genes, chromosomes, and more.

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Once the crying ended, I assured her there was a purpose for this baby. We wholeheartedly believe that our Lord and Savior gave us this beautiful baby boy to touch the lives of so many. And that HE HAS!!! Almost 8 months later and Luke Mitchell Day is as healthy and happy as any baby anyone could ever imagine.