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Columbus Arrives in the Americas; Columbian Exchange begins.

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The Treaty of Tordesillas was signed, dividing land between Spain and Portugal.

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The Atlantic Slave Trade Emerges

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The Encomienda System is established, allowing conquistadores to enslave and take the land from Natives.

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Pizarro crushes Incans

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Spanish build fortress at St. Augustine

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Elizabeth I becomes queen of England

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Iroquois Confederacy founded

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Raleigh founds "lost" colony at Roanoke Island

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England defeats Spanish Armada

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Spanish under Onate conquer Pueblo peoples of Rio Grand Valley

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James I becomes king of England

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England and Spain sign a peace treaty

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Virginia colony founded at Jamestown