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What are the Notable Pancreatic Cancer Treatment Side Effects?

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What are the Notable Pancreatic Cancer Treatment Side Effects?

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Before undergoing any pancreatic cancer treatment, ask your doctor about potential side effects to learn how they may affect you. Update your doctor if you start experiencing side effects so they can help you to relieve or reduce those effects.

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Any cancer treatment can cause side effects. Proper medical care will lessen the impacts of the side effects. Before undergoing any pancreatic cancer treatment, ask your doctor about potential side effects to learn how they may affect you. Update your doctor if you start experiencing side effects so they can help you to relieve or reduce those effects.

Here are some side effects that patients may experience during pancreatic cancer treatment:

Fatigue - often caused by an extreme lack of energy. Most pancreatic cancer patients experience this effect. The level of fatigue differs from one person to another.

Nausea and vomiting - if you are undergoing chemotherapy, then you will most likely experience nausea and vomiting. Specific treatments also have these effects. The effects might happen immediately after surgery or several days after.

Stool changes - these treatments affect your digestive system leading to constipation or diarrhea. Some of these effects will make your stool change in color.

Mouth sores - some treatments produce sores on the lips, tongue, gums, or the surface of the mouth.

Neuropathy - This is a side effect that develops numbness, burning in the hands and feet, tingling, and constipation.

Pain - Some treatments subject patients to extreme pressure and pain. Some of these treatments are radiation therapy, surgery, and chemotherapy.

Skin and nail changes - changes such as inflammation may occur during treatment. Certain treatments cause redness, dryness, tenderness, and peeling of soles and palms.

Taste and Appetite changes - Surgery and treatments such as immunotherapy, radiation therapy, and chemotherapy can cause changes in how food tastes. Patients also may develop a poor appetite that can make them lose weight.

Pancreatic cancer treatment, just like any other treatment, can cause mild to severe side effects. Your help care team will help you manage these side effects, although most of them are common among patients. Anytime you feel overwhelmed, seek medical attention.

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8 Notable Pancreatic Cancer Treatment Side Effects to Note

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Any cancer treatment can cause side effects. Proper medical care will lessen the impacts of the side effects. Before undergoing any pancreatic cancer treatment, ask your doctor about potential side effects to learn how they may affect you. Update your doctor if you start experiencing side effects so they can help you to relieve or reduce those effects.

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Do Oral Germs Predict Pancreatic Cancer?

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Do Oral Germs Predict Pancreatic Cancer?

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With a five-year survival rate of less than 10 percent and nearly 53,000 new cases diagnosed in the United States each year, pancreatic cancer is a real concern for many. Known to kill about 41,000 Americans annually, this form of cancer is among the deadliest.

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With a five-year survival rate of less than 10 percent and nearly 53,000 new cases diagnosed in the United States each year, pancreatic cancer is a real concern for many. Known to kill about 41,000 Americans annually, this form of cancer is among the deadliest. Courtesy of the location of the pancreas deep inside the body, the disease often goes undetected until long after it has begun to spread. This is complicated by very few symptoms at its onset, making early detection difficult, if not impossible, in many cases.
Researchers believe they may have found a way to better identify those who are at high-risk for the development of this disease.

Findings in a similar vein may hold the key to more accurate early detection. The findings come from studies related to the oral germs found in the mouths of pancreatic cancer. The studies found that two particular germs served as strong markers for risk. Patients who presented with one of the two oral bacterium had a 59 percent higher risk of developing pancreatic cancer than those with the second. Those with the second were about 50 percent prone to already have pancreatic cancer, studies have found.

The findings shed light on a marker that may at some point down the road serve as an early predictor for pancreatic cancer. In turn, researchers say that preventative measures can be taken to help patients at higher risk avoid the disease. Whether the findings will lead to more widespread screening tools remains to be seen. Regardless, researchers suggest the findings to point to the need for good oral hygiene and routine dental check-ups.

Pancreatic cancer continues to have one of the lowest survival rates of all forms of cancer. Researchers, however, are working hard to make advances. The connection between oral health and pancreatic cancer may someday serve as a valuable marker to give patients a chance to prevent this disease before it takes root.

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Can Oral Germs Predict Pancreatic Cancer?

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With a five-year survival rate of less than 10 percent and nearly 53,000 new cases diagnosed in the United States each year, pancreatic cancer is a real concern for many. Known to kill about 41,000 Americans annually, this form of cancer is among the deadliest.

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Give a Patient the Power of Hope and Donate Today!

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Give a Patient the Power of Hope and Donate Today!

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You can create a difference in the lives of many people through donating. Your $10 can support in building a health facility, sponsor researchers and doctors to seek further medical education or help reduce the cost of treatment.

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You can create a difference in the lives of many people through donating. Your $10 can support in building a health facility, sponsor researchers and doctors to seek further medical education or help reduce the cost of treatment.Ways through which you can donate:

Leave a legacy - You can make a lasting impact on future patients by including a research center in your bequest, will or financial plan.

Partnership - You can receive gifts by giving annual donations. Receive free cancer checks for any contribution you make above $1,000. You can also offer your services to help in caring for cancer patients, provide them with moral support, and give them hope.

Monthly donations - You can join a circle that donates monthly. Through monthly contributions, you can give hope and improve the lives of patients every month.

Host fundraising - You can create fundraising in your name. You can do this on your page and invite family and friends to donate.

Honor a loved one - you may have lost your loved one due to lack of enough financing or medical care. Empower others today by creating a personalized tribute page in your loved one's name and ask friends, colleagues, and family to donate. You will have honored your loved ones by ensuring other people benefit.

Utilize workplace giving programs - You can register with your workplace donation program. Check with your employer and subscribe to various donation programs that match with you.

Shop purple - Show pride by wearing purple to any event and encourage people to donate.

Donations to a patient, caregiver or research gives hope and confidence for a bright future. Make someone smile today.

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Give a Patient, Caregiver, Researcher, the Power of Hope - Donate Today!

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You can create a difference in the lives of many people through donating. Your $10 can support in building a health facility, sponsor researchers and doctors to seek further medical education or help reduce the cost of treatment.Ways through which you can donate: Leave a legacy - You can make a lasting impact on future patients by including a research center in your bequest, will or financial plan.

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Does Pancreatic Cysts Raise Cancer Risk? 

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Does Pancreatic Cysts Raise Cancer Risk? 

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Cysts are abnormal membrane sacs in the body that contain fluid. The pancreas is an essential organ since it produces enzymes that play a role in digestion. It also secretes insulin that regulates metabolism.

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Cysts are abnormal membrane sacs in the body that contain fluid. The pancreas is an essential organ since it produces enzymes that play a role in digestion. It also secretes insulin that regulates metabolism.

It's rare for cysts to form in the pancreas and if they do, they are typically noncancerous. Cysts often originate from different conditions, such as inflammation, and their treatment is different.
How to find pancreatic cysts
Cysts rarely have signs and symptoms, making them difficult to find. In most cases, a scan is used to discover cysts. Cysts might cause abdominal pains or lead to the development of jaundice. If detected, take cysts seriously and discuss a possible treatment plan with the doctor.
The link between cysts and pancreatic cancer
A percentage of pancreatic cysts contain a mucus-like substance called mucin which can lead to blockage of the pancreatic duct. Cysts containing mucin have a high potential of being malignant, especially if they are large with thick walls when observed through imaging. A scan alone cannot reveal cysts because some have solid and liquid components. You will need a biopsy to tell whether pancreatic cysts have malignant cells.
Treating pancreatic cysts
It is not necessary to remove cysts. Those with benign cells have no high-risk feature; thus, you will only need simple follow-ups after imaging. Imaging follow-up tests should occur after every six months. High-risk cysts can be removed through surgery, but first, you should know the risks involved, including age, health, and the nature of cells found during biopsy.
Bottomline
It's critical to consult with specialists before deciding what to do next because not all pancreatic cysts are cancerous. Visit a cancer center to do imaging and have a medical report generated. If the cysts are found to be harmful, then you will need to have them removed.

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Do Pancreatic Cysts Raise Your Risk of Cancer?

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Cysts are abnormal membrane sacs in the body that contain fluid. The pancreas is an essential organ since it produces enzymes that play a role in digestion. It also secretes insulin that regulates metabolism. It's rare for cysts to form in the pancreas and if they do, they are typically noncancerous.

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What is the Key to Targeting the Spread of Cancer?

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What is the Key to Targeting the Spread of Cancer?

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A recent study has revealed that pancreatic cancer cells quickly change their location in the body. They move to other organs, increasing the odds of pancreatic cancer death.

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A recent study has revealed that pancreatic cancer cells quickly change their location in the body. They move to other organs, increasing the odds of pancreatic cancer death. The study revealed that pancreatic tumors generate more perlecan to modify the environment around them. This allows cancer cells to spread to other organs while protecting them against chemotherapy.

The research also indicated that decreased levels of perlecan reduces the spread of cancer and increases the body's response to chemotherapy.

Pancreatic cancer is aggressive, usually making the tumor inoperable once discovered. There are two critical approaches to treating pancreatic cancer believed to increase the efficiency of chemotherapy and lower tumor spread.

Spotlight on the Tumor Matrix
An investigation to stop pancreatic cells from regeneration is done through a close look on fibroblasts. Researchers discovered that metastatic tumors produce more levels of fibroblasts than non-metastatic tumors. The discovery is that pancreatic cancer cells manifest depending on the shape of the tissue around them.

Using gene-editing technology, we can reduce the level of perlecan and use advanced imaging techniques to track pancreatic cancer cells. This will reduce the spread of cancer and increase the tumor's response to chemotherapy and other treatments.

Untapped Resources
There is hope if fibroblasts are targeted correctly through targeting cancer cells concurrently. If fibroblasts and harboring genetic changes get targeted, they will get susceptible, thus making treatment much more comfortable.

If perlecan and other matrix molecules that aid in metastatic tumors are targeted, treatment will be valid for not only pancreatic cancer but also prostate and breast cancers. Most cancer therapies focus on the cancer cells themselves, leaving the location of the tumor potentially untapped. Thus, further research is required to treat the disease quickly.

In sum, pancreatic cancer is one of the deadliest diseases. Its signs rarely show early, causing the cancer cells to spread quickly. Your physician should check the rate of spread when diagnosing the condition, and advise on effective treatment options.

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Key to Targeting the Spread of Cancer - Help Fight Pancreatic Cancer

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A recent study has revealed that pancreatic cancer cells quickly change their location in the body. They move to other organs, increasing the odds of pancreatic cancer death. The study revealed that pancreatic tumors generate more perlecan to modify the environment around them. This allows cancer cells to spread to other organs while protecting them against chemotherapy.

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Pancreatic Cancer Research and Sandler-Kenner Foundation

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Pancreatic Cancer Research and Sandler-Kenner Foundation

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The foundation has dedicated its funds on supporting and improving the survivability of pancreatic cancer patients by developing highly sensitive tools for early identification of the disease

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The Sandler-Kenner Foundation was founded in memory of Michael Sandler and Peter Kenner who succumbed to pancreatic cancer. Since then, the foundation has dedicated its funds on supporting and improving the survivability of pancreatic cancer patients by developing highly sensitive tools for early identification of the disease. They are also committed to increasing the awareness of neuroendocrine and adenocarcinoma pancreatic cancers.

The studies on pancreatic cancer are limited due to directed focus on advanced symptomatic cancer. The biomarker research is also confined to samples from symptomatic patients. It is critical that the disease is studied early before symptoms manifest in order to make advances in early detection of pancreatic cancer. The disease also has limited options for treatment, and funds are being spent to find treatments that more comprehensive and effective for all the stages of the disease.

In their efforts to initiate and support the research for early detection of pancreatic cancer, Sandler-Kenner foundation partnered with Mayo Clinic. Mayo Clinic initiated a landmark study in a trial as a novel strategy to screen for pancreatic cancer. The studies were conducted on pancreatic cancer patients at Mayo Clinic and have the potential to provide a practical approach to diagnosing the disease at an early stage to help improve life expectancy.

The research for pancreatic cancer has not had adequate funding, but various sources, including Sandler-Kenner Foundation have continued to raise funds which with time will see pancreatic patients extend their lives with innovative treatments. Sandler-Kenner Foundation still provides funding for a wider scope of more in-depth research to help change the diagnostic and treatment approaches of the disease. Though slow, new developments are evolving in all areas of pancreatic cancer.

Much time is spent on developing new methods of diagnosis and treatment of pancreatic cancer. Research is making great strides in new advances that will lead to more lifesaving developments in the treatment, prevention, and detection of this disease. With the dedication of researchers and adequate funding to support their work, more promising developments will come up to ensure that more defined ways of improving the approach to pancreatic cancer are devised.

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The Sandler-Kenner Foundation was founded in memory of Michael Sandler and Peter Kenner who succumbed to pancreatic cancer. Since then, the foundation has dedicated its funds on supporting and improving the survivability of pancreatic cancer patients by developing highly sensitive tools for early identification of the disease.

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The Connection between Teen Obesity and the Risk of Pancreatic Cancer

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The Connection between Teen Obesity and the Risk of Pancreatic Cancer

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It was discovered that obesity was linked with almost four times higher risk for cancer in men. Among the women, the risk was slightly above four times higher.  The researchers attributed to approximately 11% of pancreatic cancer cases to teenage obesity and overweight.

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Pancreatic cancer is very aggressive and has a very poor prognosis. The disease lacks diagnostic symptoms at early stages and is resistant to treatment. Recent progress has enabled scientists to define the morphological and primary genetic changes, but it's still not clear which factors trigger the occurrence of pancreatic cancer. Risk factors like genetic susceptibility,diet, fever, age, gender diabetes, race, chronic pancreatitis, and physical inactivity are well known.

Researchers reported thatteenagers who are obese are more likely to develop pancreatic cancer in their adulthood. The odds for pancreatic cancer can quadruple because of obesity. As weight increases, so does the risk and it also affects more men in high to normal weight ranges. In overall, obesity increases a person's risk for pancreatic cancer. The new finding linking adolescence obesity with the disease can impact the risk. This, though does not prove that having excess weight can cause pancreatic cancer, it's only the association of the two that exists.

According to the research:

It was discovered that obesity was linked with almost four times higher risk for cancer in men. Among the women, the risk was slightly above four times higher. The researchers attributed to approximately 11% of pancreatic cancer cases to teenage obesity and overweight.

They also reported that weight gain in teenagers could increase inflammation which damages body cells and increases cancer risk.

Studies are underway to determine whether the inflammatory process in obese cases isconnected with the inflammatory process in the malignancy. It remains a delicately balanced phenomenon for the researchers. The mechanism behind the inflammation is presumed to have grave consequences when it's not balanced.

The scientists are yet to learn more about this discovery to understand clearly the connection between obesity and cancer.

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The Connection between Teen Obesity and the Risk of Pancreatic Cancer

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Pancreatic cancer is very aggressive and has a very poor prognosis. The disease lacks diagnostic symptoms at early stages and is resistant to treatment. Recent progress has enabled scientists to define the morphological and primary genetic changes, but it's still not clear which factors trigger the occurrence of pancreatic cancer.

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Important Facts about Pancreatic Cancer Surgery 

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Important Facts about Pancreatic Cancer Surgery 

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Surgery is often the best option that enhances the survival of pancreatic cancer patients. Data has revealed that most surgeons have had great success with patients, without many complications when administering surgery.

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Surgery is often the best option that enhances the survival of pancreatic cancer patients. Data has revealed that most surgeons have had great success with patients, without many complications when administering surgery. The Pancreatic Cancer Action Network has strongly recommended that high volumes of pancreatic surgeons perform these surgeries every year.

Here are the primary facts about the pancreatic cancer surgery:

Approximately 20% of patients with pancreatic cancer are qualified for surgery at diagnosis - The pancreas is located deeper into the body between other organs. Symptoms for pancreatic cancer are vague, making it impossible to diagnose the disease in its earlier stages. At times patients who qualify for surgery are turned away. It is strongly recommended that patients see specialized surgeons (those who perform pancreatic surgery at high volumes) for them to determine their eligibility for surgery.

Pancreatic cancer patients can undergo different types of surgeries - The Whipple procedure is the most commonly used type of surgery. It is performed on patients with a tumor that is confined to the pancreas head. The other surgery options for pancreatic cancer patients include distal pancreatectomy or total pancreatectomy. These involve surgically removing part or all the pancreas respectively.

Pancreatic surgery can be combined with other treatments - Patients with pancreatic cancer can also have radiation therapy, chemotherapy or any other treatment before their surgery. Neoadjuvant therapy is given before surgery while adjuvant therapy is what a patient receives after surgery.

The surgically removed tissue can define future treatments - Tissues collected after surgery or from biopsies can be molecularly profiled. Genetic changes and protein presence will be identified alongside other actionable alterations to help predict the response of the patient to particular types of treatments.

Surgery can also be palliative - Palliative procedures help to alleviate cancer symptoms such as pain, jaundice, nausea, and vomiting. Some of the palliative procedures commonly used are gastric bypass surgery, biliary bypass surgery, and duodenal stent insertion.

The tumor size and locale within the pancreas and other factors will determine the type of surgery a patient will undergo.

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Important Facts about Pancreatic Cancer Surgery

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Surgery is often the best option that enhances the survival of pancreatic cancer patients. Data has revealed that most surgeons have had great success with patients, without many complications when administering surgery. The Pancreatic Cancer Action Network has strongly recommended that high volumes of pancreatic surgeons perform these surgeries every year.

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What are the First Signs of Pancreatic Cancer? 

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What are the First Signs of Pancreatic Cancer? 

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Pancreatic cancer can spread to other tissues and organs as well. Therefore, the symptoms depend on which location the cancer is growing. If the cancer spreads to the lungs, for example, it may cause a cough or shortness of breath.

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The pancreas plays two major roles in the body: making juices that help in digestion and making hormones such as glucagon and insulin that help in the regulation of sugar levels. The exocrine pancreas cells make digestive juices, and it's in these cells where 95% of all pancreatic cancers start. The American Cancer Society reports that pancreatic cancer accounts for about 3% of all cancers and approximately 7% of cancer deaths.

Here are the symptoms of pancreatic cancer:

Jaundice: The skin and whites of the eyes turning yellow are the indicators of jaundice. The accumulation of bilirubin, a dark yellow-brown substance produced by the liver, is what causes jaundice. Usually, the liver produces biliburin as part of bile. And bile moves through the bile duct into the intestines to help in the breakdown of fats, and it finally exits the body via stool. Cancers that begin in the head of the pancreas are usually close to the bile duct. They press on the duct, resulting in jaundice.

Dark urine: At times, the first thing to see when you have jaundice is dark urine. As the amount of bilirubin in blood rises, the urine turns to brown.

Back or belly pain: Pain in the back or abdomen is a common pancreatic cancer sign. Cancers that begin in the tail or body of the pancreas can grow big and start to press on nearby organs where they cause pain. This cancer can also spread to those nerves close to the pancreas and cause back pain.

Weight loss: People with pancreatic cancer may have no appetite, which may cause them to experience unintended weight loss.

Nausea and vomiting: The cancer can press on the stomach's far end and partly block it. This makes it hard for food to pass through. It can result in nausea, vomiting, and intense pain especially after eating.

Pancreatic cancer can spread to other tissues and organs as well. Therefore, the symptoms depend on which location the cancer is growing. If the cancer spreads to the lungs, for example, it may cause a cough or shortness of breath.

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What are the First Signs of Pancreatic Cancer?

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The pancreas plays two major roles in the body: making juices that help in digestion and making hormones such as glucagon and insulin that help in the regulation of sugar levels. The exocrine pancreas cells make digestive juices, and it's in these cells where 95% of all pancreatic cancers start.

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What You Should Know About Stage 4 Pancreatic Cancer

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What You Should Know About Stage 4 Pancreatic Cancer

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Studies show nearly 53% of patients diagnosed with pancreatic cancer are already at stage 4. Cancer stages can be established once a patient has undergone surgery. The surgery establishes the extent of cancer, how much it has spread to other body organs, and the size of the tumor.

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The pancreas is a vital organ in the body that helps in the regulation of sugar in the blood. When the pancreas develops cancer, it spreads to other parts of the body such as spleen, stomach, lungs, liver, and bowel, leading to stage 4 pancreatic cancer if no immediate medical action is taken.

Studies show nearly 53% of patients diagnosed with pancreatic cancer are already at stage 4. Cancer stages can be established once a patient has undergone surgery. The surgery establishes the extent of cancer, how much it has spread to other body organs, and the size of the tumor.

In the second and third stage, pancreatic cancer has spread to the blood vessels and the lymph nodes. Oncologists can use the size of the tumor to establish pancreatic cancer stage. All tumors below four centimeters are categorized under stage 1 pancreatic cancer. Tumor size increases depending on how far cancer has spread to other parts of the body. Note that stage 4 pancreatic cancer has no cure because it has spread to many organs in the body. At the final stage, one is put under intensive treatment to live healthily and help relieve severe pain.

Early detection of pancreatic cancer is helpful in establishing the treatment method to be applied by oncologists. Different methods can be used to treat stage 1 pancreatic cancer.

Therefore, it is advisable to seek early cancer screening. One should also take note of the possible signs and symptoms of pancreatic cancer such as weight loss, loss of appetite, yellowing of the skin, and pain in upper abdomen, to help them decide on when to seek medical attention.

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What You Should Know About Stage 4 Pancreatic Cancer

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The pancreas is a vital organ in the body that helps in the regulation of sugar in the blood. When the pancreas develops cancer, it spreads to other parts of the body such as spleen, stomach, lungs, liver, and bowel, leading to stage 4 pancreatic cancer if no immediate medical action is taken.

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Does Platinum-based Chemotherapy Improves the Survival of Pancreatic Cancer?

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Does Platinum-based Chemotherapy Improves the Survival of Pancreatic Cancer?

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The research findings highlighted the potential for harmonizing targeted therapies to groups of patients with pancreatic cancer based on their genetic makeup.

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A small study conducted on adults with common pancreatic cancer reveals that high-risk breast cancer patients with BRCA1 AND BRCA2 gene mutations have the lowest rates of survival compared to those without the mutations. The same study also discovered that the BRCA! and BRCA2 patients would survive better with platinum-based chemotherapy than those who used other kinds of drugs.

The research findings highlighted the potential for harmonizing targeted therapies to groups of patients with pancreatic cancer based on their genetic makeup.

The survival rates and therapies for patients who have pancreatic ductal adenocarcinomas (PDAC) are very poor at the moment, and such a finding that tailors better treatment for some of the patients is received with enthusiasm. Surgical removal of the tumor is currently the standard care for PDAC, but only a fraction of patients are eligible for the operation since most of the cancers don't show symptoms and are not diagnosed until they have already metastasized.

During the study:

Noncancerous tissue from 658 patients was analyzed. The patients had sporadic PDAC and had undergone operation between the year 2000 and 2015. Out of the 658, twenty-two of them (3%) had the BRCA 1 and 2 mutations in their DNA. The patients were matched by age and structural tumor locations to 105 of the other patients who had no mutations. The mid-range age was 61 years for both groups, and 62 (49%) of them were male.

Every patient in the control and mutation groups underwent a CT scan every four to six months during the first two years following the removal of the tumor, and yearly after the removal. The overall survival time from diagnosis to death was calculated.

The disease-free survival was also calculated from the time of surgery to the date of recurrence or stopped at the last follow-up date.

The pancreatic cancer patients who had the BRCA 1 and 2 mutations had an overall worse survival average of 20.2 months vs. 27.8 months, and a disease-free survival averaging 8.4 months versus 16.7 months than the patients without the mutations.

The patients who underwent platinum-based chemotherapy after surgery had better survival rates overall than those who took other treatment options or received no chemotherapy at all.

Out of the 22 patients with BRCA 1 and 2 mutations, 10 went through platinum-based chemotherapy, eight received alternative chemotherapy, and four did not receive any chemotherapy after surgery. Their survival rates averaged 31 months, 17.8 months and 9.3 months respectively.

Researchers compliment the findings, which they view as a step forward in precision medicine techniques that will match patients to better treatment options. They're looking forward to find ways of sequencing tissue from pancreatic cancer patients to help in defining the biological patterns and other patterns that will help in improving the treatment decisions. This will go a long way in reducing the soaring mortality rates of pancreatic cancer.

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How Platinum-based Chemotherapy Improves the Survival of Pancreatic Cancer

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A small study conducted on adults with common pancreatic cancer reveals that high-risk breast cancer patients with BRCA1 AND BRCA2 gene mutations have the lowest rates of survival compared to those without the mutations. The same study also discovered that the BRCA!

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Donate Your Funds to Pancreatic Cancer Research

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Donate Your Funds to Pancreatic Cancer Research

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Pancreatic cancer has numerous challenges which call for more funding to help in research that will ensure availability of better screening and treatment options.

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Pancreatic cancer, compared to other cancers, has a low profile. But then it is the third leading cause of cancer mortalities in the United States according to the American Cancer Society. Its mortality rates increase each year. Pancreatic cancer is deadly because it doesn't have early screening tests and has no cure as well. Experts say the nature of the disease makes it difficult to research.

Pancreatic cancer has numerous challenges which call for more funding to help in research that will ensure availability of better screening and treatment options.

Some of these challenges are that:

Pancreatic cancer is rapidly lethal. The disease does not behave like other cancers, so the treatment approaches used on other cancers don't work well on pancreatic tumors.

Not many pancreatic cancer survivors can create awareness campaigns and publicize fundraising events to help combat the disease. This is because most of them die within a short period of diagnosis. It is difficult to find and retain pancreatic cancer patients for clinical trials and further research because of its metastasizing speed.

There's little time for the patients and their families to absorb the diagnosis before the patient succumbs to the disease.

Pancreatic cancer has been underfunded and understudied because it is a little bit of a Catch-22 for scientists and clinicians studying it. The best thing a doctor can offer a pancreatic cancer patient is optimism and hope.

The resistance mechanism in pancreatic cancer is that it decreases the supply of blood instead of increasing it the way other cancers do.

Clinical staging system of pancreatic cancer is not clear-cut. Even when caught at early stages, the disease requires complicated surgery (Whipple procedure), and after surgery, the l0-year survival rate is less than 10%. The disease ends up metastasizing because even the early tumors will have already spread. They get to the bloodstream and find ways to survive in other body organs including at the microscopic level.

Pancreatic cancer does not trigger the immune system, making it difficult to detect through lab tests.

Recent discoveries have made the disease more understandable. Researchers have begun to look for more ways to out-think the tricky disease cells using immunotherapy techniques and molecular biology. Techniques are underway to help target particular aspects of the tumor cell of the pancreas that will prime it to be receptive to drug therapies used in other cancers.

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Why You Should Donate Your Funds to Pancreatic Cancer Research

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Pancreatic cancer, compared to other cancers, has a low profile. But then it is the third leading cause of cancer mortalities in the United States according to the American Cancer Society. Its mortality rates increase each year. Pancreatic cancer is deadly because it doesn't have early screening tests and has no cure as well.

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Neoadjuvant Therapy and Survival Rates of Pancreatic Cancer

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Neoadjuvant Therapy and Survival Rates of Pancreatic Cancer

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Research reports that patients with locally advanced pancreatic cancer have longer overall survival when they undergo surgical resection after neoadjuvant therapy.

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Research reports that patients with locally advanced pancreatic cancer have longer overall survival when they undergo surgical resection after neoadjuvant therapy. The development of advanced systematic treatments of radiotherapy and chemotherapy, patients with non-metastatic locally advanced pancreatic cancer have an increased chance for surgery and improved survival.

Locally advanced pancreatic cancer accounts for 30% of newly diagnosed pancreatic cancers and is surgically unresectable because of involvement of adjacent vessels. The current guidelines recommend that patients with good performance status be given non-operative treatment. Studies suggest that patients with locally advanced pancreatic cancer (LAPC) can be cured if given resection after induction chemotherapy.

The research was carried out on 415 patients with LAPC to confirm if surgical resection after neoadjuvant therapy was associated with improvement in survival rates compared to aggressive non-operative management. Thirteen patients underwent surgical exploration based on the response of tumor to neoadjuvant therapy, and to another 103 patients who had no signs of the progression or metastases of local disease after four months of neoadjuvant therapy.

Eighty-four patients achieved the resection of the primary tumor (72% of patients eligible for exploration and 20% of all LAPC patients). Resection was aborted intraoperatively in 12 patients who showed occult abdominal metastatic disease and in 20 patients because of local extension of the tumor. In 89% of the cases, resection margins showed negative for tumor (R0).

After resection, 40 patients developed recurrence of the disease, 13 patients with most commonly local recurrence and nine patients had distant liver metastases.

The median survival during diagnosis was 35.3 months for the group under resection and 16.2 months for the 331 patients who were treated with radiation therapy and chemotherapy.

The overall survival rates were significantly higher in the resected group at one year (96%) and three years (50%) than in the non-resected group which had 74% at one year and 11% at three years.

The overall results showed that the patients had comparable survival after the neoadjuvant therapy and surgery to those with the initially resectable disease which was a significant improvement. However, LAPC patients under neoadjuvant therapy treatment need to be monitored and repeatedly assessed to identify those who can be taken to surgery. Doctors concluded that aggressive neoadjuvant therapy could help in reducing tumor and making surgery feasible.

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Neoadjuvant Therapy and Surgery Improves Survival of Pancreatic Cancer

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Research reports that patients with locally advanced pancreatic cancer have longer overall survival when they undergo surgical resection after neoadjuvant therapy. The development of advanced systematic treatments of radiotherapy and chemotherapy, patients with non-metastatic locally advanced pancreatic cancer have an increased chance for surgery and improved survival.

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Prevention can combat the rising rates of pancreatic cancer. According to some doctors, 30% of pancreatic cancer can be prevented by better diets, more exercise, no smoking and cutting back on obesity.

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Pancreatic cancer accounts for almost three percent of all cancers and is considered deadly due to its low survival rate. The disease at its early stages rarely shows any symptoms, and there are no specific screening tools to identify pancreatic cancer. Even after undergoing surgery, 30% of pancreatic cancer still goes undetected, leaving a possibility for the cancer to recur five years after surgery.

Here's information about the rising rates of pancreatic cancer:

Pancreatic cancer was the fourth leading cause of cancer mortality in the U.S.

Currently, pancreatic cancer is the third leading cause of cancer deaths, and even with the rising survival rates, it's expected to become the second leading cause.

The incidence of pancreatic cancer has risen by approximately 0.5% each year for more than a decade. This is according to the National Cancer Institute.

The rise in mortality rank of pancreatic cancer can be partly explained by the advances in treating other cancer types particularly prostate, breast and colon cancer. Immunotherapy has still not worked for pancreatic and liver cancer.

Over three-quarters of new pancreatic cancer patients are aged between 55 and 84 years old, meaning that the aging population is the main contributor.

Smoking is the most significant contributor to the development of pancreatic cancer. Even though smoking rates have dropped in the U.S., it will be 30 to 40 years before we experience a proportionate drop in the rates of pancreatic cancer.

The increase in type 2 diabetes and obesity have contributed to the rise in pancreatic cancer. According to Robert A. Wolf, MD, obesity has overtaken smoking as the primary cause of the increase in pancreatic cancer.

Pancreatic tumors metastasize quickly unlike many other cancers which can be cured if detected early. Liquid biopsies and precision medicines are hot areas of oncology, but pancreatic cancer is difficult to treat effectively.

Some doctors believe that patients will be helped by precision medicine therapies, especially the 10% who have hereditary pancreatic cancer. The current blood tests cannot specify though.

Prevention can combat the rising rates of pancreatic cancer. According to some doctors, 30% of pancreatic cancer can be prevented by better diets, more exercise, no smoking and cutting back on obesity.

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10 Things to Know About Rising Rates of Pancreatic Cancer

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Pancreatic cancer accounts for almost three percent of all cancers and is considered deadly due to its low survival rate. The disease at its early stages rarely shows any symptoms, and there are no specific screening tools to identify pancreatic cancer.

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For some years, research has focused on understanding the appropriate balance of good bacteria within the intestinal tract.

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For some years, research has focused on understanding the appropriate balance of good bacteria within the intestinal tract. Links between the onset of disease and gut dysbiosis are getting established with the hope of developing therapeutic interventions to halt the progression of the disease. Investigators have released data to describe how bacteria population in the pancreas increases largely in patients with pancreatic cancer to be dominated by species that block the immune system from attacking tumor cells.

Findings from a new study indicated that:

Removing bacteria from the pancreas and gut by treating mice with antibiotics reprogrammed immune cells and slowed the cancer growth to identify cancer cells.

Oral antibiotics increased the efficacy of checkpoint inhibitors, a form of immunotherapy that had failed in the clinical trials of pancreatic cancer before to produce a strong antitumor shift in immunity.

Bacteria change the immune environment around the cancer cells to allow them to grow faster in some patients than others even when they have the same genetics.

In patients with pancreatic ductal adenocarcinoma (PDA) - cancer that turns fatal within two years - pathogenic gut bacteria moves to the pancreas through the pancreatic duct.

Once in the pancreas, the abnormal microbiome releases cellular components that shut down the immune system to promote the growth of cancer.

The research was carried out to understand the immune suppression in pancreatic cancer and its reversal. Ongoing studies are meant to confirm the species of bacteria that can shut down the immune reaction to cancer cells and set the stage for new diagnostic tests that are bacteria-based, a combination of immunotherapy and antibiotics, and maybe for probiotics that prevent cancer in patients who are high-risk.

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How Microbiome Promotes the Progression of Pancreatic Cancer

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For some years, research has focused on understanding the appropriate balance of good bacteria within the intestinal tract. Links between the onset of disease and gut dysbiosis are getting established with the hope of developing therapeutic interventions to halt the progression of the disease.

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Brush Your Teeth Twice a Day and Reduce Your Risk of Illnesses Including Pancreatic Cancer

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Brush Your Teeth Twice a Day and Reduce Your Risk of Illnesses Including Pancreatic Cancer

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With recent studies linking gum disease to other illnesses that may occur, it can be highly beneficial to brush your teeth at least two times a day. One of these diseases is Pancreatic Cancer, and the maintenance of oral hygiene can ensure that your risk of getting the disease could be reduced.

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With recent studies linking gum disease to other illnesses that may occur, it can be highly beneficial to brush your teeth at least two times a day. One of these diseases is Pancreatic Cancer, and the maintenance of oral hygiene can ensure that your risk of getting the disease could be reduced.

Gum disease connected with cancer of the mouth: Swedish research scientists have stated that gum disease is clearly associated with not only mouth cancer, but numerous other types of cancers in the body as well. If you manage to catch the presence of periodontitis as soon as possible, you can reduce the risk of getting other cancers in the future.

These bacteria aid in the damaging of tissues, similar to that seen in cancer: Thanks to the sheer capability of the bacteria found in periodontitis to be highly virulent, they can spread throughout the body from the mouth. This may manifest as the mouth is inflamed, and due to this, the bacteria can pervade the rest of the body, all the way to the pancreas. Apart from it being vital to practice good oral hygiene, it can make a difference to your total health. Gum disease symptoms include bleeding when brushed, and bad smelling breath. It can also lead to damaging your jawbone, as well as an eventual loss of teeth.

More than ten thousand diagnoses of pancreatic cancer pop up each year: There are more than ten thousand cases of pancreatic cancer diagnosed each year. The disease manifests itself by pains in the stomach region or the back. Sudden weight-loss is also a symptom. The most prominent sign is when the eyes and the person's skin turn yellow.

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If You Brush Your Teeth Twice a Day, Reduce Your Risk of Illnesses

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With recent studies linking gum disease to other illnesses that may occur, it can be highly beneficial to brush your teeth at least two times a day. One of these diseases is Pancreatic Cancer, and the maintenance of oral hygiene can ensure that your risk of getting the disease could be reduced.

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New and More Precise Medical Approach for Treating Metastasized Pancreatic Cancer

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New and More Precise Medical Approach for Treating Metastasized Pancreatic Cancer

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Columbia University recently received a 3-year grant to sponsor a single-phase clinical experiment of a precise medicinal approach to help in treating metastasized pancreatic cancer. The current treatments that are prominently used attack the mutated DNA which is assumed to drive the tumor growth in patients.

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Columbia University recently received a 3-year grant to sponsor a single-phase clinical experiment of a precise medicinal approach to help in treating metastasized pancreatic cancer. The current treatments that are prominently used attack the mutated DNA which is assumed to drive the tumor growth in patients. This is mostly effective in patients who suffer from the commonest types of pancreatic cancer, and for those with less seen cancer types, it is not that effective.

Reduced effectiveness of older treatment can be seen: In the case of pancreatic duct carcinomas, only fifteen percent of patients get benefits from conventional methods of treatment, and the others will either not show a response or show a relapse, due to the cancer showing drug resistance.

New method studies the RNA instead of the DNA of the cancer cell: Due to older approaches towards treating the disease proving ineffectual, research scientists plan to conduct studies of the tissue specific copies of DNA of cancer cells, called the RNA, instead of analyzing the DNA. This should provide a better image, with better accuracy of the various genetic factors inside a tumor which promote it continuously surviving. The patients, depending on this analysis, can be given personalized treatment.

More effective treatment by matching drugs with patient's case: Going by the results of preliminary tests of the above method, the research scientists have managed to match one or more drugs to patients in eighty five percent of cases. This treatment is useful in identifying the different drugs which can reverse the actions of some hidden cancer targets. One of these is known as a master regulating protein which is responsible for giving cancer cells immunity from typical cancer treatments.

The grant is also being utilized for the funding of a preclinical study of patients of pancreatic ductal carcinoma, and developing an individualized drug treatment plan for them.

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New Medical Approach for Treating Metastasized Pancreatic Cancer

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Columbia University recently received a 3-year grant to sponsor a single-phase clinical experiment of a precise medicinal approach to help in treating metastasized pancreatic cancer. The current treatments that are prominently used attack the mutated DNA which is assumed to drive the tumor growth in patients.

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How a Texas Pancreatic Cancer Network Association Change Lives

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How a Texas Pancreatic Cancer Network Association Change Lives

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Pancreatic cancer is one of the most insidious and alarming types of cancer. Since it doesn’t manifest any symptoms until its later stages, detection of it can prove extremely difficult. Even when it is detected, it is often too late and it may be hard to get effective treatment.

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Pancreatic cancer is one of the most insidious and alarming types of cancer. Since it doesn't manifest any symptoms until its later stages, detection of it can prove extremely difficult. Even when it is detected, it is often too late and it may be hard to get effective treatment.

Pancreatic cancer is the third most dangerous type of cancer. It kills more that ninety percent of the patients it inflicts in less than 5 years and is even more mortality causing than breast cancer. More than fifty thousand Americans are diagnosed with the disease every single year.

Texas pancreatic cancer association networks manage to save a great deal of lives with the work they do. They have undertaken a multipronged approach towards dealing with pancreatic cancer and ensuring that the people it afflicts survive. They have been working tirelessly to help patients and their loved ones live healthy lives.

They approach the issue on multiple fronts: To make sure that they can prevent as many fatalities as possible, these association networks play several important roles. These include investing in research and clinical initiatives, as well as legal aid and services geared towards patients. A nationwide net of support, aids their community financially and otherwise. Their ultimate aim is to improve quality of life for the patient both today, as well as in the future, and increase the survival rate as much as possible.

They function in a systematic manner: The patients afflicted by pancreatic cancer need and ought to get good treatment, and thus improve their lives. This can only happen when there is research. Research in turn needs a good scientific community to thrive.

Awareness of pancreatic cancer should spread everywhere to raise the knowledge of the disease, as well as to obtain contributions to help cure it. The pancreatic cancer associations also do this.

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How a Texas Pancreatic Cancer Network Association Change Lives

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Pancreatic cancer is one of the most insidious and alarming types of cancer. Since it doesn't manifest any symptoms until its later stages, detection of it can prove extremely difficult. Even when it is detected, it is often too late and it may be hard to get effective treatment.

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Diagnosing and Treating Pancreatic Cancer

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Diagnosing and Treating Pancreatic Cancer

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There are multiple options to fight pancreatic cancer, and support groups for patients offer incredible courage and hope. Knowing the procedures and symptoms is the first step to curing yourself.

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The American Cancer Society says that more than 50,000 people will be diagnosed with pancreatic cancer this year in the U.S. Besides, pancreatic cancer is the third leading cause of cancer-related deaths, and is often diagnosed only in the advanced stages, because of the difficulties to detect the late symptoms. The oncology experts at the Honor Health Research Institute offer guided and detailed expertise to enable one to identify the symptoms right away.

Types of pancreatic cancer: There are two kinds of cells in the pancreas, including exocrine pancreas cells and endocrine pancreas cells, which form different types of tumors. The National Cancer Institute states that most pancreatic cancers form in the exocrine cells, which make enzymes that are released into the small intestine to help the body digest food.
According to the American Cancer Society, about 95 percent of cancers of the exocrine pancreas are adenocarcinomas, which usually start in the ducts of the pancreas.

Signs and symptoms: Experts opine that individuals with pancreatic cancer often do not experience any symptoms, making it extremely difficult to detect the disease. While not all people with pancreatic cancer show any symptoms, some may experience jaundice, unexplained weight loss, stomach or back pain, loose stool, and trouble digesting high fat foods.

Risk factors: Family history and genetics are an important element, as are diabetes and obesity that increase the risk of the disease. Smoking and heavy drinking are other factors.

Treatment: Diagnosis with pancreatic cancer has multiple treatment options, such as surgery, chemotherapy, radiation therapy or immunotherapy. Clinical trials for individuals at every stage of their pancreatic cancer journey are also available at the Honor Health Research Institute.

There are multiple options to fight pancreatic cancer, and support groups for patients offer incredible courage and hope. Knowing the procedures and symptoms is the first step to curing yourself.

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Diagnosing and Treating Pancreatic Cancer

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The American Cancer Society says that more than 50,000 people will be diagnosed with pancreatic cancer this year in the U.S. Besides, pancreatic cancer is the third leading cause of cancer-related deaths, and is often diagnosed only in the advanced stages, because of the difficulties to detect the late symptoms. The oncology experts at the Honor Health Research Institute offer guided and detailed expertise to enable one to identify the symptoms right away.

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These foundations run on the basis of charity and donations received from the public. Donations of any size are welcomed as it all counts and make a difference towards the eradication of this disease.

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Of all the major cancers, the mortality rate of pancreatic cancer is the highest in the United States of America. Statistics show that within five years of pancreatic cancer diagnosis, almost 94% of the patients die. The population that survives for more than five years is only 6%. Within their first year, 74% of patients pass away of being diagnosed with pancreatic cancer. Pancreatic cancer is a lethal and deadly disease.

Charities and foundations have understood that it is vital to change these statistics. They make it their mission to find out precise ways for the early detection of this disease. The Texas pancreatic cancer foundation's ultimate goal is to find an early detection method and a cure.

Foundations are not only focused on research and investigation. They also work towards raising awareness about the risks and symptoms of pancreatic cancer. In the month of November, Pancreatic Cancer Awareness Month is celebrated where foundations try to spread knowledge and understanding about pancreatic cancer and its prevention.

Even though the treatments of various kinds of cancer have been enhanced and greatly developed, there has not been much success in pancreatic cancer. This type of cancer is often diagnosed when it has reached its late stage, which makes it pretty hard to treat.

Texas pancreatic cancer foundations and charitable organizations want to give their fellow Texans hope and restore their faith that treatment and cure can be possible for pancreatic cancer.

The pancreas is an oblong, spongy organ located between the spine and the stomach. The pancreas is an important organ in our body because it helps in digestion and regulates blood sugar.

Cancer foundations are on their way in making groundbreaking research on treatment and cures for pancreatic cancer. Innovative treatments, such as targeted therapies and proton therapy are being developed and improved so that the chances of fighting pancreatic cancer become higher.

Texas pancreatic cancer foundations also participate in clinical trials. These trials are studies that examine new treatments to see if they are beneficial for pancreatic cancer patients. Foundations give pancreatic cancer patients, the opportunity to participate in these clinical researches.

These foundations run on the basis of charity and donations received from the public. Donations of any size are welcomed as it all counts and make a difference towards the eradication of this disease. Millions are spent on research, trying to find a cure for pancreatic cancer.

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Texas Pancreatic Cancer Foundation's Charity and Donations

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Of all the major cancers, the mortality rate of pancreatic cancer is the highest in the United States of America. Statistics show that within five years of pancreatic cancer diagnosis, almost 94% of the patients die. The population that survives for more than five years is only 6%.