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Agonists  1.

Alpha 1: Adrenergic Agonists

Ephedrine

Phenylephrine (Neo-Synephrine)

Adrenergic Agonists

Epinephrine (Adrenalin)

Beta 1  Adrenergic Agonists

Dobutamine

Beta 2 Adrenergic Agonists

Formoterol

Albuterol

Terbutaline

Salmeterol

Antagonists

Alpha 1: Adrenergic Blocking

Prazosin

Terazosin

Doxazosin

Beta 1 Adrenergic Blocking Drugs

Selective: Atenolol, Metoprolol

Non selective: Nadolol , Propranolol , Timolol

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Agonists: Acting Cholinergic Agonists

Direct

Acetylcholine

Pilocarpine

Bethanechol

Indirect

Neostigmine

Antagonists/ Anticholinergic

Atropine

Dicyclomine

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Heart:

Decreased heart rate and AV conduction

Slight decrease in contractility

Intestines, GI, motility, and secretion

Increased

Postganglionic neurotransmitter

Acetylcholine is released

Pupil of Eye

Constriction

Respiratory passages

Bronchoconstriction

Urinary bladder

Contraction

Urinary sphincter

Relaxation

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Adrenal Medulla  1.

Causes the release of epinephrine and norepinephrine

Arteries:

Vasoconstriction

Heart:

Increases heart rate, and AV conduction

Increases contractility

Intestines,

GI motility, and secretions

Decreased digestion, slow GI motility, and slow secretions

Postganglionic neurotransmitter

Norepinephrine

Pupil of Eye

Dilation/mydriasis

Respiratory passages

Bronchodilation

Urinary Bladder

Relaxation

Urinary sphincter

contraction, leads to decreased urination

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Muscarinic

Location:cardiac, smooth muscle and glands, they’re in parasympathetic nerve endings

Nicotinic 1 (Nn)

Location: at the ganglia of parasympathetic nerves and sympathetic nerves

Nicotinic 2 (Nm)

Location: somatic, neuromuscular junction of skeletal muscles

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Alpha 1

Main Location: glands, smooth muscle, eye, most arteries and veins

Alpha 2:

main location: brain

Beta 1:

main location: the heart

Beta 2:

main location: Smooth muscles, lings, uterus, skeletal muscle arteries, coronary arteries

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ACH and Acetylcholine: They are released at gangliac and postgangionic nerve endings

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Acetylcholine: Released at the ganglia, from presynaptic nerve endings

Norepinephrine:  Released at postganglionic nerve endings

Epinephrine: Acts on adrenergic receptors  2. Produced by adrenal medulla

Dopamine: Sympathetic and CNS neurotransmitter

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Parasympathetic Nervous System  (Cholinergic) 

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Parasympathetic Nervous System  (Cholinergic) 

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Sympathetic Nervous System (Adrenergic) 

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Sympathetic Nervous System (Adrenergic) 