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https://www.medicalnewstoday.com/articles/325644.php

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As soon as someone drinks alcohol, it starts to run through the bloodstream. The liver is able to filter out the alcohol unless someone continues to drink. Drinking alcohol can destroy brain cells and cause further brain damage.

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Blood Vessels - You can have high blood pressure;stroke
Stomach - Ulcers causing stomach cancer
Heart - Irregular heart rate causing heart-muscle damage
Liver - Scarring and liver cancer both causing death
Brain - Memory loss;nervous system disorders
Kidneys - Kidney Failure

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Blood Vessels - Widens vessels making you less warm
Stomach - Can causing vomiting
Heart - Heart rate increases
Liver - Alcohol becomes unbalanced between the whole body
Brain - Alcohol poisoning;judgment;low concentration
Kidneys - Increased urination