# data[].attributes.body
Ingelvac Aujeszky MLV
- A modified live Pseudorabies vaccine, containing Bartha K-61 strain.

# data[].attributes.body
Growing Swine (2 - 4th Day)

1. Listless

2. Depressed

3. Remain recumbent

5th Day

1. Incoordination and Pronounced Muscle Spasm

2. Circling

3. Excess Salivation

6th Day

1. Moribund

2. Die within 12 hours

Mature Swine

1. Low mortality <2%

2. Weight loss

3. Poor growth rates after recovery

# data[].attributes.body
There is a focus of neuronal necrosis (N),cuffing (arrow) within the periventricular grey matter

# data[].attributes.body
Lesions on post-mortemed lung

# data[].attributes.body
Rhinitis in snout of pig with Pseudorabies

# data[].attributes.body
Vaccination

1. Recommended: Modified live vaccine

Can alleviate clinical sign

2. Intranasal Vaccination + IM Vaccination

1. To reduce viral shedding & improve survival

Management

1. Separation for 30 days

Blood testing until it is confirm negative

2. Biosecurity measures

Limitation entry

3. Disinfect area, attire & equipment

Pseudorabies can be inactivated using approved disinfectant

# data[].attributes.body
1. Immunofluorescent antibody (IFA)

Source: Tonsil or brain

2. Polymerase Chain Reaction (PCR)

3. Serology (Used for confirmation)

Source: Brain, spleen & lung

4. Enzyme – linked Immunosorbent Assay (ELISA)

approved as a standard test and association with vaccination and eradication programs

# data[].attributes.body
1. The only lesions that can be seen by naked eye are those in the lungs and respiratory tubes and areas of necrosis on the tonsils and abdominal organs

Tonsillitis

Tracheitis

Rhinitis

Esophagitis

Discrete small white or yellow foci necrosis may be present in liver and spleen

2. Pseudorabies damage the pig’s nerve system but this lesion can only be see through a microscope, not with naked eye.

There is a diffuse non-supportive meningoencephalitis and ganglioneuritis

Marked perivascular cuffing

Focal gliosis associated with extensive necrosis of neuronal and glial cells

# data[].attributes.body
Pregnant Sow

1. Abortion

2. Late pregnancy: Deliver a mixture of mummified, macerated, stillborn, weak & normal swine

Piglet

1. High mortality

Born with non – immune dam

Younger Swine (48 hours)

1. Sneezing

2. Coughing

3. Moderate fever (40 - 42˚C

4. Constipation during fever

5. Vomiting

# data[].attributes.body
Transmission

1. Direct

Nose to nose contact / fecal oral route (Licking/biting)

2. Indirect

Aerosolized virus (Capable to spread over 20 yards, 2 km in certain weather conditions)

3. Fomites & vectors

Dead end hosts (dogs/cats/wildlife/contaminated water & feed, including pellets/ food troughs/ boots that are not disinfected/straw bedding)

Dead rats ingested can also be a source of infection (especially to dogs and cats)

4. Shown to survive

7 hours in humid air

7 days in unchlorinated water

Up to 3 days in contaminated feed

Up to 2 days in grass / soil / faeces

Up to 4 days in straw bedding

# data[].attributes.body
1. Alphavirus in a subfamily of Herpesvirus

2. Neurotropism

3. Group I dsDNA

4. Genus: Varicellovirus

5. Species: Suid Herpes virus -1

6. Enveloped Virus

7. Swine is the only reservoir host

But the virus can infect other animals

Infection of horses are rare

8. Often persists in a latent state in recovered animals

9. Moderately resistant outside the host, survival depending largely on environmental factors

Cold weather: Virus does not survive outside swine more than 2 weeks

Exceptionally survive longer in infected fetuses, dried tissue & buildings