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By: Armando Cruz, and Sebastian

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•The name of the disorder is progeria also called the Hurchinson Gilford Progeria syndrome (HGPS). This disorder is found in children and newborns. Progeria is an extremely rare disorder and occurs in one in every 8 million babies born worldwide.

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•Some signs and symptoms of progeria are hair loss, wrinkles, slow growth, delayed tooth development, high pitched voice, enlarged head, and visible veins. Progeria affects the musculoskeletal system, cardiovascular system, and the skin. The nucleus of the cell is affected by progeria by making an abnormal Lamin A protein called progeria.

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•Progeria is diagnosed with a genetic test made specifically for it. Progeria can also be diagnosed by observing the physical symptoms or signs like an enlarged head, visible veins, wrinkles, or dryness, hair loss, and slow growth. The expected life span of someone with progeria (HGPS) is 13 years old.

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•Progeria comes from the greek word progerus which signifies prematurely old. Progeria is currently diagnosed with genetic testing but used to be diagnosed only by physical signs and observations. Progeria was discovered in 1886 by two doctors by the name of Hasting Gilford and Jonathan Hutchinson.

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•Progeria is caused by a point mutation in position 1824 of a gene known as the LMNA gene. The gene is responsible for making a protein to help support the cell. Progeria is not sex linked and can happen in families with no link to the disorder at all.

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•Progeria is not due to any heredity of any sort and is not a nondisjunction. The conclusion is that the cause of the disorder is most likely a mutation.

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•Progeria has no treatment that can cure the disease but certain medication and therapy to help patients coupe with the symptoms of the disease that reduce complications caused by the disorder. Some drugs like Lonafarnib are being researched and shows promise.

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•Some of the technology that might be used in the future to fight progeria deal with repair of DNA using methods such as non-homogeus and joining. This future technology may help us fix the part of the affected gene that causes progeria.

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When the gene responsible for LMNA causes a different form of Lamin which affects the cell as it is not originally what it needs. Progeria is not normally family transmitted.

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•"About Progeria." The Progeria Research Foundation. N.p., n.d. Web. 24 May 2017.

•"Progeria." Wikipedia. Wikimedia Foundation, 21 May 2017. Web. 24 May 2017.

•"Progeria." Mayo Clinic. Mayo Foundation for Medical Education and Research, 27 Apr. 2017. Web. 24 May 2017.

•http://www.webmd.com/children/progeria#1. 24 May 2017