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How come the tribes trusted these random people (Lewis + Clark) to settle down in their area, how did they know that these people were here with no wrong intentions?

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What made everyone think there would be the Northwest Passage Waterway? Did the rumors spread that far or was it an educated guess?

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Why would lewis off himself?

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What role did the Constitution play in Thomas Jefferson's decision, and confliction, about the Louisiana Purchase?

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How did the expedition impact the relationship between the United States and Native American tribes?