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 Initiates gene transcription for mRNA that promotes thyroid hormone response. 

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 Initiates gene transcription for mRNA that promotes thyroid hormone response. 

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Passes through outer membrane of a tissue cell

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Passes through outer membrane of a tissue cell

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 Binds to Thyroid Hormone Receptor and Retinoid X Receptor (RXR). 

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 Binds to Thyroid Hormone Receptor and Retinoid X Receptor (RXR). 

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T4 and T3 are transported in the blood vessels by binding to thyroid binding proteins and are transported around the bloodstream to various tissue. 

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T4 and T3 are transported in the blood vessels by binding to thyroid binding proteins and are transported around the bloodstream to various tissue. 

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TSH binds to G-Protein in Thyroid Membrane. GDP is exchanged for GTP, increasing cAMP levels, increasing thyroid hormone production.

Iodine binds to the tyrosine rings in thyroglobuline, forming T3 and T4

They enter follicular cells through pinocytosis, causing lysosomes to separate the T4 and T3.

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Forms hormone receptor complex and binds to DNA 

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Forms hormone receptor complex and binds to DNA 

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The mRNA leaves nucleus and synthesize proteins while the proteins increase metabolic rate. 

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The mRNA leaves nucleus and synthesize proteins while the proteins increase metabolic rate. 

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Causes:
Growth
CNS Development in brain cells Increased metabolic rate Increased cardiac output Increased respiration